12 results for "Shayan Forghani"
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Journal Article
Assessment of ESR1, PGR, ERBB2, and MKI67 mRNA in Hormone Receptor‐Positive Early Breast Cancer: A Cross‐Sectional Study
ABSTRACT Background and Aims Hormone receptors are expressed in 70% of breast cancers and are the major biomarkers for tailoring treatment in early‐stage breast cancer. In clinical routine, immunohistochemistry (IHC) is used to assess estrogen receptor (ER), progesterone receptor (PR), HER2, and…
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Journal Article
Ultrasound evaluation of gallbladder wall thickness for predicting severe dengue: a systematic review and meta-analysis
Abstract Background The prevalence of dengue fever (DF), a mosquito-borne viral disease, is rising worldwide. Its severe manifestations like thrombocytopenia and plasma leakage are associated with increased mortality. Ultrasound-detected gallbladder wall thickening (GBWT) has been suggested as a…
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Journal Article
Post-transplant cyclophosphamide as graft-versus-host disease prophylaxis for matched related donor hematopoietic stem cell transplantation in acute leukemia: a systematic review and meta-analysis
Although allogeneic hematopoietic stem cell transplantation (HSCT) offers curative potential for acute leukemia, graft-versus-host disease (GVHD) remains a major obstacle to optimal clinical outcomes. Evidence for post-transplant cyclophosphamide (PTCy) in the matched related donor (MRD) setting is…
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Journal Article
Comparison of machine learning models with conventional statistical methods for prediction of percutaneous coronary intervention outcomes: a systematic review and meta-analysis
Abstract Introduction Percutaneous coronary intervention (PCI) has been the main treatment of coronary artery disease (CAD). In this review, we aimed to compare the performance of machine learning (ML) vs. logistic regression (LR) models in predicting different outcomes after PCI. Methods Studies…
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Journal Article
The correlation between cardiac T2*MRI and B-Type natriuretic peptides in patients with transfusion-dependent anemias and systemic iron overload: a systematic review and meta-analysis
Objectives Systemic iron overload in transfusion-dependent anemias leads to progressive myocardial iron accumulation, a major cause of morbidity and mortality. This study evaluated the relationship between cardiac T2* magnetic resonance imaging (MRI) values and natriuretic peptide levels in…
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Journal Article
Clinical Significance of Tumor Invasion Gene Profiling in Early‐Stage Hormone Receptor‐Positive Breast Cancer: A Cross‐Sectional Study
ABSTRACT Background and Aims Advanced breast cancer is a leading cause of cancer‐associated death in women. It is critical to find biomarkers to identify patients who are more prone to progress to advanced disease and would be better served with more aggressive treatments. Hormone receptor‐positive…
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Journal Article
Current advances and challenges in mpox vaccine development: a global landscape
Given the surge in mpox outbreaks in 2022 and the advancements in domestic and international vaccine research, the effectiveness of smallpox vaccines in providing cross-protection against mpox remains crucial. Having learned from the COVID-19 pandemic, it is significant to continue evaluating…
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Journal Article
Computed tomography of interstitial lung disease in systemic sclerosis: dataset and deep learning model for pulmonary lesion segmentation
Objective. Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is a major cause of morbidity and mortality in systemic sclerosis patients. High-resolution computed tomography (HRCT) plays a crucial role in SSc-ILD diagnosis and management. In this study, we aimed to develop and…
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Journal Article
Botulinum Toxin (Dysport) to Prevent Radiation‐Induced Dysfunction of Salivary Glands in Head and Neck Cancer
ABSTRACT Background The main goal of this pilot trial was to investigate the efficacy of botulinum toxin (Dysport) injection before radiotherapy in preserving salivary gland secretion in patients with head and neck cancer. Methods Sixteen patients with head and neck cancer were enrolled, 9 received…
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Journal Article
The prognostic and clinical utility of circulating tumor DNA in diffuse large B-cell lymphoma: a systematic review and meta-analysis
Abstract Circulating tumor DNA (ctDNA) provides a minimally invasive tool for assessing tumor burden and genetic evolution in diffuse large B-cell lymphoma (DLBCL). This systematic review and meta-analysis evaluated 53 studies reporting the association of ctDNA and survival outcomes. High ctDNA…