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6 hasil untuk "Shuning Guo"

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  1. Artikel Jurnal

    Pathogenesis exploration of lgG4-related disease: From the traditional central dogma and its remodeling perspective

    Shuning Guo; Jing Li; Wen Zhang dkk.

    Chinese Medical Journal, Vol. 139 No. 13 · 2026 · Inggris · DOAJ Scopus

    Abstract. Immunoglobulin G4-related disease (IgG4-RD) is a chronic disease characterized by inflammation and fibrosis within multiple organs. The fundamental immunopathogenic mechanisms of IgG4-RD remain largely unidentified. Advancements in multiple omics technologies have enabled researchers to…

  2. Artikel Jurnal

    Noncoding RNAs in Drug Resistance of Gastrointestinal Stromal Tumor

    Jiehan Li; Shuning Guo; Zhenqiang Sun dkk.

    Frontiers in Cell and Developmental Biology, Vol. 10 · 2022 · Inggris · DOAJ Scopus

    Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the gastrointestinal tracts and a model for the targeted therapy of solid tumors because of the oncogenic driver mutations in KIT and PDGDRA genes, which could be effectively inhibited by the very first targeted agent…

  3. Artikel Jurnal

    Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis

    Shuning Guo; Jiehan Li; Shurui Pang dkk.

    Arthritis Research & Therapy, Vol. 27 No. 1 · 2025 · Inggris · DOAJ Scopus

    Abstract Background Advances in treatment have swiftly alleviated systemic inflammation of Takayasu’s arteritis (TAK), while subclinical vascular inflammation and the ensuing arterial remodeling continue to present unresolved challenges in TAK. The phenotypic switching of vascular smooth muscle…

  4. Artikel Jurnal

    Analysis of Quality Differences in Congou Black Tea Processed from Mixed Summer and Autumn Fresh Leaves of Different Varieties

    Shuning GUO; Haoming ZUO; Chenyu SHAO dkk.

    Shipin gongye ke-ji, Vol. 46 No. 15 · 2025 · Tionghoa · DOAJ Scopus

    This study selected and processed three widely promoted tea varieties in Hunan Province—Zhuyeqi, Xiangfeicui, and Fuding Dabaicha—into seven congou black tea samples using traditional congou black tea processing techniques. The processing was conducted in three ways: single variety, a mixture of…

  5. Artikel Jurnal

    Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth

    Yizheng Zhang; Chuchu Zhang; Jiehan Li dkk.

    Cell Communication and Signaling, Vol. 20 No. 1 · 2022 · Inggris · DOAJ Scopus

    Abstract Background Targeting AKT suppresses tumor growth through inducing apoptosis, however, during which whether other forms of cell death occurring is poorly understood. Methods The effects of increasing PARP1 dependent cell death (parthanatos) induced by inhibiting AKT on cell proliferation…

  6. Artikel Jurnal

    The preliminary exploration of composition origin of solid solution alloys used in thermocouple by cluster-plus-glue-atom model

    Zhihui Liu; Qizhen Wang; Shuning Guo dkk.

    Materials & Design, Vol. 216 · 2022 · Inggris · DOAJ Scopus

    The chemical composition proportion of solid solution alloys in thermocouples (TCs) field is preliminarily explored by the cluster-plus-glue-atom (CPGA) model. CPGA clusters for face-centered cubic (fcc) and body-centered cubic (bcc) structure elemental metal are established, which are the cubic…