87 hasil untuk "Ulla Feldt-Rasmussen"
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Artikel Jurnal
Importance of iodide sufficiency and normal thyroid function in fertility and during gestation
Abstract Appropriate management of thyroid dysfunction in pregnancy is challenging in both its primary, secondary and tertiary forms of the disease. Primary hypothyroidism is by far most prevalent globally. Main causes are insufficiency of iodide supplementation in developing countries and…
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Artikel Jurnal
The Influence of Triclosan on the Thyroid Hormone System in Humans - A Systematic Review
ObjectivesTriclosan is an antibacterial agent suspected to disrupt the endocrine system. The aim of this study was to investigate the influence of triclosan on the human thyroid system through a systematic literature review of human studies.MethodsEligibility criteria and method of analysis were…
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Artikel Jurnal
Levothyroxine Therapy in Elderly Patients With Hypothyroidism
Levothyroxine (L-T4) treatment of overt hypothyroidism can be more challenging in elderly compared to young patients. The elderly population is growing, and increasing incidence and prevalence of hypothyroidism with age are observed globally. Elderly people have more comorbidities compared to young…
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Artikel Jurnal
Recent advances in understanding autoimmune thyroid disease: the tallest tree in the forest of polyautoimmunity [version 1; referees: 2 approved]
Autoimmune thyroid disease (AITD) is often observed together with other autoimmune diseases. The coexistence of two or more autoimmune diseases in the same patient is referred to as polyautoimmunity, and AITD is the autoimmune disease most frequently involved. The occurrence of polyautoimmunity has…
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Artikel Jurnal
Thyroid Autoimmunity and Function after Treatment with Biological Antirheumatic Agents in Rheumatoid Arthritis
With the increased pro-inflammatory response in both rheumatoid arthritis and thyroid autoimmune diseases, treatment with biological antirheumatic agents (BAAs) of the former may affect the course of the latter. In hepatitis C and cancer patients, treatment with biological agents substantially…
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Artikel Jurnal Teks lengkap
Dizziness in Fabry Disease
Background/Objectives: Fabry disease is an X-linked lysosomal storage disease. Earlier studies have mentioned dizziness/balance issues and vestibular involvement as a symptom of Fabry disease. Research on the matter remains scarce. This pilot study aims to show the prevalence of dizziness/balance…
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Artikel Jurnal
Insulin Independence in Newly Diagnosed Type 1 Diabetes Patient following Fenofibrate Treatment
A 19-year-old girl was diagnosed with type 1 diabetes and showing polydipsia and polyuria. She was double autoantibody-positive and had a diabetes-prone tissue type. She was immediately started on insulin. Fenofibrate treatment (160 mg daily) was initiated seven days after diagnosis. The need for…
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Artikel Jurnal
Health-related quality of life and patterns of psychological vulnerability in autoimmune Addison’s disease: a systematic review
BackgroundAutoimmune primary adrenal insufficiency (PAI) is the most common cause of Addison’s disease (AD) in Western countries and requires lifelong glucocorticoid and mineralocorticoid replacement. Despite biochemical control, many patients report persistent fatigue, functional limitations, and…
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Artikel Jurnal
Less known aspects of central hypothyroidism: Part 2 – Congenital etiologies
Central hypothyroidism (CH) occurs approximately in 1:50,000, and therefore is expected to be one thousand times rarer compared with primary hypothyroidism. Despite its rarity in the general population, it is much more common in certain disorders, in which it is frequently associated with other…
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Artikel Jurnal
Semen quality in patients with pituitary disease and adult-onset hypogonadotropic hypogonadism
Objective: Gonadotropins (luteinizing hormone (LH) and follicle-stimulating hormone (FSH)) are released from the pituitary gland and stimulate Leydig cells to produce testosterone and initiates spermatogenesis. Little is known about how and when the deterioration of semen quality occurs in patients…
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Artikel Jurnal
Less known aspects of central hypothyroidism: Part 1 – Acquired etiologies
Central hypothyroidism (CH) is a rare cause of hypothyroidism. CH is frequently overlooked, as its clinical picture is subtle and includes non-specific symptoms; furthermore, if measurement of TSH alone is used to screen for thyroid function, TSH concentrations can be normal or even above the upper…
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Artikel Jurnal
Predictive factors and the management of hyperglycemia in patients with acromegaly and Cushing’s disease receiving pasireotide treatment: post hoc analyses from the SOM230B2219 study
IntroductionPasireotide, a somatostatin receptor ligand, is approved for treating acromegaly and Cushing’s disease (CD). Hyperglycemia during treatment can occur because of the drug’s mechanism of action, although treatment discontinuation is rarely required. The prospective, randomized, Phase IV…
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Artikel Jurnal
Alexithymia, Emotional Distress, and Perceived Quality of Life in Patients With Hashimoto’s Thyroiditis
Emotion-processing impairment represents a risk factor for the development of somatic illness, affecting negatively both health-related quality of life (HRQoL) and disease management in several chronic diseases. The present pilot study aims at (i) investigating the associations between alexithymia…
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Artikel Jurnal
Plasma cortisol cut-off concentrations using the dexamethasone suppression test in patients with adrenal incidentalomas
PurposeAssessment of cortisol secretion in patients with adrenal incidentalomas remains challenging. We evaluated the guideline-recommended cortisol cut-off value for cortisol suppression (50 nmol/L) following a 1 mg overnight dexamethasone suppression test (DST) against a control-derived threshold…
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Artikel Jurnal
Hyperinsulinaemic hypoglycaemia - a diagnostic challenge. A report of two atypical cases.
Objectives: The authors describe 2 atypical cases of patients with hypoglycaemia, suspected for insulinoma. Methods: The 2 reports are accompanied by a concise review of the literature. Results: Patient 1 had a distal pancreatectomy performed for suspected insulinoma, and was diagnosed with a…
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Artikel Jurnal
Thyroid function monitoring during pregnancy in euthyroid women with thyroid autoimmunity
Background: Thyroid autoimmunity (TAI) may be present in 1–17% of pregnant women. Monitoring of thyroid function in euthyroid pregnant women positive for anti-thyroperoxidase antibodies (TPOAb+) is recommended. Objective: To determine the prevalence and possible clinical and biological risk factors…
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Artikel Jurnal
Clinical management of female patients with Fabry disease based on expert consensus
Abstract Fabry disease is an X-linked lysosomal storage disorder that causes accumulation of glycosphingolipids in body tissues and fluids, leading to progressive organ damage and life-threatening complications. It can affect both males and females and can be classified into classic or later-onset…
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Artikel Jurnal Teks lengkap
Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo
Ghrelin is a peptide hormone produced mainly in the gastrointestinal tract known to regulate several physiological functions including gut motility, adipose tissue accumulation and hunger sensation leading to increased bodyweight. Studies have found a correlation between the plasma levels of…
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Artikel Jurnal Teks lengkap
Positron Emission Tomography and Magnetic Resonance Imaging of the Brain in Fabry Disease: A Nationwide, Long-Time, Prospective Follow-Up
Background: Fabry disease is a rare metabolic glycosphingolipid storage disease caused by deficiency of the lysosomal enzyme α-galactosidase A—leading to cellular accumulation of globotriasylceramide in different organs, vessels, tissues, and nerves. The disease is associated with an increased risk…
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Artikel Jurnal
Genotype–phenotype associations in PPGLs in 59 patients with variants in SDHX genes
Phaeochromocytomas and paragangliomas (PPGLs) are tumours of the adrenal medulla and extra-adrenal sympathetic nervous system which often secrete catecholamines. Variants of the SDHX (SDHA, -AF2, -B, -C, -D) genes are a frequent cause of familial PPGLs. In this study from a single tertiary centre…