3 hasil untuk "Valentin Dunsing-Eichenauer"
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Artikel Jurnal
Spatial patterning of contractility by a self-organized mechanogen activity gradient underlies Drosophila gastrulation
Abstract During development cell deformations are spatially organized, however, how cellular mechanics is spatially controlled is unclear. Spatial control of cell identity often determines local cellular mechanics in a two-tiered mechanism. Theoretical studies also proposed that molecular…
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Artikel Jurnal
A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales
Whole-mount 3D imaging at the cellular scale is a powerful tool for exploring complex processes during morphogenesis. In organoids, it allows examining tissue architecture, cell types, and morphology simultaneously in 3D models. However, cell packing in multilayered organoid tissues hinders both…
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Artikel Jurnal
Fast volumetric fluorescence lifetime imaging of multicellular systems using single-objective light-sheet microscopy
Abstract Fluorescence lifetime imaging (FLIM) is widely used for functional and multiplexed bioimaging. The lifetime of autofluorescence or fluorescent sensors encodes physiologically relevant parameters. Thus, FLIM is especially relevant for the investigation of living systems. However…