40.148 hasil
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Artikel Jurnal Teks lengkap
Hepatocellular carcinoma: signaling pathways and therapeutic advances
Liver cancer represents a major global health concern, with projections indicating that the number of new cases could surpass 1 million annually by 2025. Hepatocellular carcinoma (HCC) constitutes around 90% of liver cancer cases and is primarily linked to factors incluidng aflatoxin, hepatitis B…
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Artikel Jurnal Teks lengkap
Liver diseases: epidemiology, causes, trends and predictions
As a highly complex organ with digestive, endocrine, and immune-regulatory functions, the liver is pivotal in maintaining physiological homeostasis through its roles in metabolism, detoxification, and immune response. Various factors including viruses, alcohol, metabolites, toxins, and other…
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Artikel Jurnal Teks lengkap
Pattern recognition receptors: function, regulation and therapeutic potential
Pattern recognition receptors (PRRs) are sensors in the immune system, detecting pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). They serve as essential links between the innate and adaptive immune responses, initiating defense mechanisms against…
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Bab Buku Teks lengkap
Mass Transfer in Multicomponent Mixtures
13 1.2What this Book covers 14 1.3 Structure of the Book 15 1.4 Guidelines to the Reader 16 1.5 Guidelines to the Teacher 17 1.6 Symbols 18 1.7 Conventions 21 2 is SOMETHING WRONG?24 2.1 The Starting Point 24 2.2 Three Gases 26 2.3 Two Cations 28 2.4 Two Gases and a Porous Plug 2.5 Summary 2.6…
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Artikel Jurnal Teks lengkap
Aging, longevity, and healthy aging: the public health approach
BACKGROUND: Population aging is one of the most significant global demographic changes of the 21st century, driven by increased life expectancy and declining fertility rates. This phenomenon presents both achievements and challenges for public health systems worldwide. AIMS: On the one hand…
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Artikel Jurnal Teks lengkap
A foundation model for atomistic materials chemistry
Atomistic simulations of matter, especially those that leverage first-principles (ab initio) electronic structure theory, provide a microscopic view of the world, underpinning much of our understanding of chemistry and materials science. Over the last decade or so, machine-learned force fields have…
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Artikel Jurnal Teks lengkap
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
Cyclin Dependent Kinases (CDKs) are closely connected to the regulation of cell cycle progression, having been first identified as the kinases able to drive cell division. In reality, the human genome contains 20 different CDKs, which can be divided in at least three different sub-family with…
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Artikel Jurnal Teks lengkap
The distribution of subsurface microplastics in the ocean
Marine plastic pollution is a global issue, with microplastics (1 µm–5 mm) dominating the measured plastic count1,2. Although microplastics can be found throughout the oceanic water column3,4, most studies collect microplastics from surface waters (less than about 50-cm depth) using net tows5…
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Artikel Jurnal Teks lengkap
The STARD-AI reporting guideline for diagnostic accuracy studies using artificial intelligence
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Artikel Jurnal Teks lengkap
One-quarter of freshwater fauna threatened with extinction
Abstract Freshwater ecosystems are highly biodiverse 1 and important for livelihoods and economic development 2 , but are under substantial stress 3 . To date, comprehensive global assessments of extinction risk have not included any speciose groups primarily living in freshwaters. Consequently…
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Artikel Jurnal Teks lengkap
Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), is a growing but often unrecognized medical problem for people with diabetes (particularly type 2 diabetes, especially when associated with obesity). Liver health has…
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Artikel Jurnal Teks lengkap
The GSA Family in 2025: A Broadened Sharing Platform for Multi-omics and Multimodal Data
The Genome Sequence Archive family (GSA family) provides a comprehensive suite of database resources for archiving, retrieving, and sharing multi-omics data for the global academic and industrial communities. It currently comprises four distinct database members: the Genome Sequence Archive (GSA…
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Artikel Jurnal Teks lengkap
Der vollkommene Capellmeister
Johann Mattheson (1681-1764) var den tyske baroks førende musikteoretiker og -kritiker. Han var selv sanger, musiker og komponist, men havde desuden en bred uddannelsesbaggrund og fungerede det meste af sit voksne liv som sekretær for den engelske ambassadør i Hamburg. Han udgav Critica Musica…
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Artikel Jurnal Teks lengkap
Type 2 Diabetes Mellitus: New Pathogenetic Mechanisms, Treatment and the Most Important Complications
Type 2 diabetes mellitus (T2DM), a prevalent chronic disease affecting over 400 million people globally, is driven by genetic and environmental factors. The pathogenesis involves insulin resistance and β-cell dysfunction, mediated by mechanisms such as the dedifferentiation of β-cells…
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Artikel Jurnal Teks lengkap
Challenging Cognitive Load Theory: The Role of Educational Neuroscience and Artificial Intelligence in Redefining Learning Efficacy
Background/Objectives: This systematic review integrates Cognitive Load Theory (CLT), Educational Neuroscience (EdNeuro), Artificial Intelligence (AI), and Machine Learning (ML) to examine their combined impact on optimizing learning environments. It explores how AI-driven adaptive learning…
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Artikel Jurnal Teks lengkap
Helicobacter pylori and gastric cancer: mechanisms and new perspectives
Gastric cancer remains a significant global health challenge, with Helicobacter pylori (H. pylori) recognized as a major etiological agent, affecting an estimated 50% of the world's population. There has been a rapidly expanding knowledge of the molecular and pathogenetic mechanisms of H. pylori…
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Artikel Jurnal Teks lengkap
The evolving field of digital mental health: current evidence and implementation issues for smartphone apps, generative artificial intelligence, and virtual reality
The expanding domain of digital mental health is transitioning beyond traditional telehealth to incorporate smartphone apps, virtual reality, and generative artificial intelligence, including large language models. While industry setbacks and methodological critiques have highlighted gaps in…
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Artikel Jurnal Teks lengkap
Triboelectric tactile sensor for pressure and temperature sensing in high-temperature applications
Skin-like sensors capable of detecting multiple stimuli simultaneously have great potential in cutting-edge human-machine interaction. However, realizing multimodal tactile recognition beyond human tactile perception still faces significant challenges. Here, an extreme environments-adaptive…
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Artikel Jurnal Teks lengkap
Hydrogen Storage Technology, and Its Challenges: A Review
This paper aims to present an overview of the current state of hydrogen storage methods, and materials, assess the potential benefits and challenges of various storage techniques, and outline future research directions towards achieving effective, economical, safe, and scalable storage solutions…
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Artikel Jurnal Teks lengkap
IDF Diabetes Atlas 11th edition 2025: global prevalence and projections for 2050
Bruce B Duncan, Dianna J Magliano, Edward J Boyko; IDF diabetes atlas 11th edition 2025: global prevalence and projections for 2050, Nephrology Dialysis Tr
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