46 results for "Li-Rong Lin"

Erratum to: Novel predictors of neurosyphilis among HIV-negative syphilis patients with neurological symptoms: an observational study

Yao Xiao; Man-Li Tong; Li-Li Liu et al.

BMC Infectious Diseases, Vol. 17 No. 1 · 2017 · English · DOAJ Scopus

Novel predictors of neurosyphilis among HIV-negative syphilis patients with neurological symptoms: an observational study

Yao Xiao; Man-Li Tong; Li-Li Liu et al.

BMC Infectious Diseases, Vol. 17 No. 1 · 2017 · English · DOAJ Scopus

Abstract Background Known predictors of neurosyphilis were mainly drawn from human immunodeficiency virus (HIV)-infected syphilis patients, which may not be applicable to HIV-negative populations as they have different characteristics, particularly those with neurological symptoms. This study aimed…

LncRNA Expression in CD4+ T Cells in Neurosyphilis Patients

Li-Li Liu; Shao-Gang Zhu; Xiao-Yong Jiang et al.

Frontiers in Cellular and Infection Microbiology, Vol. 7 · 2017 · English · DOAJ Scopus

Recent studies have shown that several long noncoding RNAs (lncRNAs) are involved in regulating the immune response to cope with pathogenic invasion. To date, the roles of lncRNAs in the CD4+ T cell response to Treponema pallidum (T. pallidum) infection in neurosyphilis patients remain unknown. The…

Development of tissue inflammation accompanied by NLRP3 inflammasome activation in rabbits infected with Treponema pallidum strain Nichols

Li-Rong Lin; Yao Xiao; Wei Liu et al.

BMC Infectious Diseases, Vol. 18 No. 1 · 2018 · English · DOAJ Scopus

Abstract Background The inflammasome responses in Treponema pallidum infection have been poorly understood to date. This study aimed to investigate the expression of the nucleotide-binding leucine-rich receptor protein 3 (NLRP3) inflammasome in the development of tissue inflammation in rabbits…

Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Li-Rong Lin; Wei Liu; Xiao-Zhen Zhu et al.

BMC Immunology, Vol. 19 No. 1 · 2018 · English · DOAJ Scopus

Abstract Background The involvement of inflammasome activation and macrophage polarization during the process of syphilis infection remains unknown. In this study, A series of experiments were performed using human macrophages to research the role of NLRP3 inflammasome regulation in interleukin…

Advancing Precise Syphilis Diagnosis: A Nontreponemal IgM Antibody-Based Model for Latent Syphilis Staging

Xie JW; Guo YF; Zheng YW et al.

Infection and Drug Resistance, Vol. Volume 17 · 2024 · English · DOAJ Scopus

Jia-Wen Xie,1,2 Yin-Feng Guo,1,2 Ya-Wen Zheng,1,3 Mao Wang,1,2 Qiu-Yan Xu,1,2 Yu-Yan Chen,1,2 Li-Rong Lin1,2,4 1Center of Clinical Laboratory, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, People’s Republic of China; 2Institute of Infectious Disease, School of…