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A survey of student loan burden among United States Chiropractors: Insights on debt, relief, and educational value
Background: Although student loans have made health professional education accessible for a greater proportion of the US population, rising student indebtedness has incited considerable discourse. This study aimed to characterize US chiropractors’ self-reported student loan debt, student loan…
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The impact of government macroeconomic policies and elections on income smoothing in state-controlled commercial banks: Evidence from the MENA region
In most of the economies of different countries in the world, banks play a very important role in economic stability. We know that if the banks are not managed correctly, this issue will have heavy economic, political and social consequences for the society of that country. If we can find the…
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Maternal Zika virus exposure and neurodevelopmental outcomes: A longitudinal study of preschool children in the ZIKAlliance Colombian Cohort
Background: Zika virus (ZIKV) infection has been inconsistently associated with neurodevelopmental delay (ND). We aimed to compare the incidence of ND between ZIKV-exposed and ZIKV-unexposed children within the ZIKAlliance (ZA) cohort, in Colombia, assessed 2 years after birth (2018–2021). Methods…
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Human brains construct individualized global rankings from identical few-shot learning input
Ranking—a ubiquitous relational structure—enables humans to organize complex information and overcome cognitive load, yet in real-world settings it is often inferred from sparse, few-shot learning of local pairwise relationships. How the human brain performs relational inference under such limited…
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Sensitivity analysis of factors influencing the ecology of mosquitoes involved in the transmission of Rift Valley fever virus
Vector-borne diseases are a major global health concern, with Rift Valley fever (RVF) serving as a key example due to its impact on both human and animal health. Predicting and controlling such diseases requires understanding how environmental factors shape mosquito ecology. Due to mosquito…
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Clostridioides difficile colonization amplification despite limited in-hospital transmission: A modeling study
Background: Although healthcare-associated transmission of Clostridioides difficile is a recognized public health concern, community-onset infections represent an important component of the overall disease burden. This paradox likely reflects the underappreciated interplay between these settings…
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Chronic replication stress-mediated genomic instability disrupts placenta development in mice
Abnormal placentation drives many pregnancy-related pathologies and poor fetal outcomes, but the underlying molecular causes are understudied. Here, we show that persistent replication stress due to mutations in the MCM2–7 replicative helicase disrupts placentation and reduces embryo viability in…
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Nonlinear effects of noise on outbreaks of mosquito-borne diseases
Mosquito-borne diseases are a significant and growing public health burden globally. Predictions about the spread and impact of mosquito-borne disease outbreaks can help inform direct control and prevention measures. However, climate change is expected to increase weather variability, potentially…
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Microbiota-derived indole differentially shapes Entamoeba histolytica physiology and promotes host-compatible colonization
Entamoeba histolytica is a pathogenic amoeba that colonizes the human large intestine and causes amoebiasis. In its natural gut environment, the parasite is exposed to microbiota-derived metabolites, including indole, a tryptophan-derived compound present at millimolar concentrations, whereas…
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MultiMindNet: AI-based mental health analysis using hybrid deep learning approach and Hybrid Ant-Grey Wolf Optimization (HAGWO) algorithm
Mental health disorders like depression and anxiety pose global challenges, requiring accurate, non-invasive detection methods. Classical modes of diagnosis are typically based on self-reported symptoms or clinical evaluation, which could be subjective and protracted in time. To address these…
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Ventricular activation and repolarization in response to physiological and conventional pacing using ultra-high-frequency electrocardiography
Background: Physiological pacing targeting the cardiac conduction system is increasingly being adopted as an alternative to conventional right ventricular (RV) pacing for the treatment of bradyarrhythmias, although its effects on ventricular repolarization remain underexplored. Objective: This…
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Enhancing Recommendation Systems through SVD-based collaborative filtering and community detection
The recommendation systems often face challenges like low data density, scalability issues and absence of interpretability, whereas classical Collaborative Filtering (CF) which is based on Singular Value Decomposition (SVD) shows support by being scalable, weakened frequently in circumstances of…
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ZmSKIP enhances drought tolerance by reducing stomatal aperture in maize
SKI-INTERACTING PROTEINS (SKIPs), primarily known as splicing factors, control gene expression at the post-transcriptional level in stress responses in plants. However, little is known about SKIPs in regulating plant drought stress at the transcriptional level, particularly in maize (Zea mays L.)…
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Poxvirus A52 protein subverts autophagy flux by blocking autophagosome–lysosome fusion to promote viral replication
Many poxviruses are significant zoonotic pathogens threatening public health. Autophagy, a regulated process vital for cellular homeostasis, can participate in defense against virus invasion. However, the relationship between poxviruses and host cell autophagy is not fully understood. This study…
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Productivity and quality-related traits of wheat germplasm affected by heat stress
Heat stress (HS) significantly impedes wheat production, making the development of heat-tolerant cultivars increasingly essential in the context of climate change. This study evaluated 153 elite spring wheat (Triticum aestivum L.) genotypes from the Wheat Association Mapping Initiative (WAMI) panel…
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Pelvic floor exercise: Awareness, knowledge, beliefs and practices among pregnant women in a Ghanaian setting
Background: Pregnancy and childbirth increase the risk of pelvic floor muscle damage, leading to conditions such as urinary incontinence, fecal incontinence, and pelvic organ prolapse. This makes it imperative to adopt strategies such as pelvic floor muscle exercises (PFMEs) to ensure positive…
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Comparison of methods for determining parameters related to ankle joint quasi-stiffness during quiet standing
Ankle joint quasi-stiffness is a measure representing the control of quiet standing. Here we investigated three methods for determining parameters associated with ankle joint quasi-stiffness. Eleven healthy, young males were asked to stand quietly with eyes open (EO) and eyes closed (EC). Ankle…
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Effect of dialysate buffer practices on serum parathyroid hormone concentrations in real-life french patients receiving hemodialysis
Background: Dialysate composition is crucial for managing secondary hyperparathyroidism (SHPT) in patients on hemodialysis. Acetate‐based dialysates elevate serum acetate and trigger adverse effects, while citrate and hydrochloric acid formulations might offer distinct clinical benefits. Methods…
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