10 results for "Li-Ling Lin"
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Journal Article
Placental mesenchymal dysplasia complicated with sudden fetal demise and amniotic fluid embolism: a case report
Abstract Background Placenta mesenchymal dysplasia (PMD) is a rare placental anomaly associated with various fetal and maternal complications. Whether close ultrasound surveillance can prevent intrauterine fetal demise (IUFD) in patients with PMD is still under investigation. Amniotic fluid…
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Journal Article
Unraveling fetal venous disorders: An integrated approach in fetal echocardiography and their clinical significance
Objective: Fetal venous system malformations frequently coincide with cardiac or extracardiac anomalies. This study explores our experience with an integrated fetal echocardiography approach and analyzes the characteristics and outcomes of fetal venous system disorders. Materials and methods: We…
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Journal Article
Assessment of adverse pregnancy outcomes associated with Helicobacter pylori infection
Abstract The background of Helicobacter pylori (H. pylori) infection is complex, and its influence on adverse pregnancy outcomes is inconsistently reported. We performed a multi-institutional, retrospective analysis using de-identified electronic health records from the TriNetX Research Network to…
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Journal Article
Operando X‐Ray Absorption Spectroscopy Reveals Dynamic Interfacial Metal–Metal Coordination Governing CO2 Reduction Selectivity in PdAg Alloys
ABSTRACT Achieving high selectivity towards single carbon products in electrochemical CO2 reduction requires precise control over intermediate binding energies, a challenge that monometallic catalysts cannot address due to inherent electronic structure limitations. Bimetallic catalyst offers a…
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Journal Article
Mendelian randomization analyses support causal relationship between brain imaging-derived phenotypes and risk of low back pain
Low back pain (LBP) has long been the leading cause of worldwide productivity loss and the top cause of years lived with disability. Observational studies have reported associations between brain imaging-derived phenotypes (IDPs) and LBP; however, it is uncertain whether these relationships are…
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Journal Article
SMR Analysis Integrating GWAS and eQTL Data Reveals UHRF1BP1 and SNRPC as Potential Drug Targets for Low Back Pain
Xiao-Yan Xie,1,2,* Jian-Wei Lin,3,* Peng-Cheng Li,1,* Jia-Yu Fang,1 Zhuo-Chen Chen,1 Xiao-Yan Huang,1 Ming-Hui Cao,1,2 Li-Ling Lin,1 Ming-Yan Guo1,21Department of Anesthesiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2Shenshan…
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Journal Article
Application of whole genome sequencing for carrier and diagnostic assessment of spinal muscular atrophy in Taiwan
Abstract This study aimed to evaluate the feasibility of whole-genome sequencing (WGS) combined with computational tools for spinal muscular atrophy (SMA) carrier screening and disease diagnosis in Taiwan. WGS data from 1492 Taiwan Biobank participants and two patients with SMA were analysed to…
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Journal Article
AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages
Summary: Tumor-associated macrophages (TAMs) are integral to the development of complex tumor microenvironments (TMEs) and can execute disparate cellular programs in response to extracellular cues. However, upstream signaling processes underpinning this phenotypic plasticity remain to be…
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Journal Article
Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination
Abstract While macrophage phagocytosis is an immune defense mechanism against invading cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel this engulfment. Here we report that the reverse signaling using CD47 as a receptor additionally enhances a pro-survival…