30 hasil untuk "Yu-Ri CHOI"

Antimicrobial Resistance and PFGE Molecular Typing of Salmonella enterica serovar Gallinarum Isolates from Chickens in South Korea from 2013 to 2018

Jun-Feng Zhang; Ke Shang; Jong-Yeol Park dkk.

Animals, Vol. 12 No. 1 · 2021 · Inggris · DOAJ Scopus

Antimicrobial resistance and pulsed-field gel electrophoresis (PFGE) genotypes of collected S. enterica ser. Gallinarum isolates were investigated to examine the epidemiological relationship between field outbreak isolates of S. enterica ser. Gallinarum. Thirty S. enterica ser. Gallinarum isolates…

Genetic Characterization of Avian Paramyxovirus Isolated from Wild Waterfowl in Korea between 2015 and 2021

Yea-Jin Lee; Jong-Yeol Park; Ke Shang dkk.

Animals, Vol. 14 No. 5 · 2024 · Inggris · DOAJ Scopus

Avian paramyxoviruses (APMVs) are often carried by wild waterfowl, and the wild waterfowl may play an important role in the maintenance and spread of these viruses. In this study, we investigated APMVs in the population of migratory wild waterfowl from 2015 to 2021 in Korea and analyzed their…

Antigenic Matching of rHVT-H5 via CRISPR/Cas9 Confers Complete Protection Against Novel H5N1 Clade 2.3.4.4b in Chicken

Sang-Won Kim; Jong-Yeol Park; Ji-Eun Son dkk.

Veterinary Sciences, Vol. 13 No. 2 · 2026 · Inggris · DOAJ Scopus

The widespread panzootic of clade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 necessitates the development of vaccine platforms capable of rapid adaptation to emerging antigenic variants. Although commercial recombinant turkey herpesvirus (rHVT) vaccines are available, they often utilize…

Preclinical immunogenicity testing using anti-drug antibody analysis of GX-G3, Fc-fused recombinant human granulocyte colony-stimulating factor, in rat and monkey models

Yun Jung Kim; Eun Mi Koh; Chi Hun Song dkk.

Scientific Reports, Vol. 11 No. 1 · 2021 · Inggris · DOAJ Scopus

Abstract Human granulocyte colony-stimulating factor (G-CSF, this study used Fc-fused recombinant G-CSF; GX-G3) is an important glycoprotein that stimulates the proliferation of granulocytes and white blood cells. Thus, G-CSF treatment has been considered as a crucial regimen to accelerate recovery…

Long-Term Immunogenicity and Protection of a rHVT-H9/Y280 Vaccine Against H9N2 Avian Influenza Virus in Commercial Layers with High Maternal Antibodies

Sang-Won Kim; Jong-Yeol Park; Ji-Eun Son dkk.

Animals, Vol. 16 No. 2 · 2026 · Inggris · DOAJ Scopus

The endemicity of H9N2 avian influenza viruses (AIVs), particularly the Y280 lineage, poses persistent challenges to the poultry industry due to the limitations of inactivated vaccines, such as interference by maternally derived antibodies (MDAs) and incomplete suppression of viral replication…

Discovery of plasma biomarkers for predicting the severity of coronary artery atherosclerosis by quantitative proteomics

Eu Jeong Ku; Kyung-Cho Cho; Jeong Won Kang dkk.

BMJ Open Diabetes Research & Care, Vol. 8 No. 1 · 2020 · Inggris · DOAJ Scopus

IntroductionCardiovascular disease (CVD) in patients with diabetes is the leading cause of death. Finding early biomarkers for detecting asymptomatic patients with CVD can improve survival. Recently, plasma proteomics—targeted selected reaction monitoring/multiple reaction monitoring analyses…

Cholesterol Efflux and Collateral Circulation in Chronic Total Coronary Occlusion: Effect‐Circ Study

Seonhwa Lee; Jung Mi Park; Soo‐Jin Ann dkk.

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 10 No. 5 · 2021 · Inggris · DOAJ Scopus

Background The mechanism through which high‐density lipoprotein (HDL) induces cardioprotection is not completely understood. We evaluated the correlation between cholesterol efflux capacity (CEC), a functional parameter of HDL, and coronary collateral circulation (CCC). We additionally investigated…

A Mutation in PMP2 Causes Dominant Demyelinating Charcot-Marie-Tooth Neuropathy

Young Bin Hong; Jaesoon Joo; Young Se Hyun dkk.

PLOS Genetics, Vol. 12 No. 2 · 2016 · Inggris · PLOS Scopus

Charcot-Marie-Tooth disease (CMT) is a heterogeneous group of peripheral neuropathies with diverse genetic causes. In this study, we identified p.I43N mutation in PMP2 from a family exhibiting autosomal dominant demyelinating CMT neuropathy by whole exome sequencing and characterized the clinical…

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Novel syngeneic model of anti-mouse CLDN18.2 CAR -T therapy for gastric cancer demonstrates a synergy with TGF-β and PD-L1 inhibitors

Min-Jung Seo; Jin Hue Jeong; Han Na Park dkk.

Molecular Therapy: Oncology, Vol. 34 No. 1 · 2026 · Inggris · DOAJ Scopus

There are very few syngeneic mouse cell line models available for gastric cancer owing to the rarity of stomach epithelium-specific promoter. Mouse cell line models are useful to study an immunologically intact tumor microenvironment, especially in the setting of CAR-T studies that often use…