52 hasil untuk "Fu-Rong Li"
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Artikel Jurnal
Menopausal characteristics and hormone replacement therapy in relation to long-term risk of cholecystectomy in women
BackgroundWomen are known to be at higher risk for gallbladder disease than men, suggesting a role of female hormones in the pathogenesis of gallbladder disease. This study aimed to assess menopausal characteristics, hormone replacement therapy (HRT) and their joint effect on long-term risk of…
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Artikel Jurnal
Diabetes duration, glycemic control, and risk of stroke and stroke subtypes: a nationwide prospective cohort study
Abstract To evaluate the relationship of diabetes duration and glycemic control with risk of stroke and its major subtypes using data from the UK Biobank, a large population-based cohort of UK adults. We included 23,401 UK adult residents with diabetes who had no known stroke at baseline…
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Artikel Jurnal
Dissecting the multi-omics atlas of the exosomes released by human lung adenocarcinoma stem-like cells
Abstract Lung adenocarcinoma is heterogeneous and hierarchically organized, with a subpopulation of stem-like cells (CSCs) that reside at the apex of the hierarchy, in which exosomes act as important mediators by transporting specific molecules among different cell populations. Although there have…
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午睡与2型糖尿病风险之间的关联受到炎症和肥胖的调节:来自英国生物样本库(UK‐Biobank) 435 342名参与者的证据
Abstract Background Existing evidence concerning the relationship between daytime napping and type 2 diabetes (T2D) is inconsistent, and whether the effects of napping differ by body fat percentage (BFP) and C‐reactive protein (CRP) is unclear. We aimed to investigate the association between…
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在中国非糖尿病或糖尿病患者中，用不同的方法评估肾小球滤过率和全因死亡率的风险:一项全国性的前瞻性研究
Abstract Background Whether estimated glomerular filtration rates (eGFRs) by differing biomarkers are differentially associated with mortality or whether the associations differ by diabetes status remains unclear, especially in Chinese population. Methods We included 6995 participants without…
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Artikel Jurnal
Physical activity, muscle strength, sedentary behavior, sleep, and genetic risk of stroke and dementia: findings from a large cohort study
Abstract Background Physical activity, grip strength, sedentary behaviors, and sleep duration were found to be associated with risk of developing stroke and dementia. However, the combined influence of these factors on stroke and dementia remains unclear. Objective To investigate the combined…
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Artikel Jurnal
Physical activity and sleep pattern in relation to incident Parkinson’s disease: a cohort study
Abstract Background How physical activity (PA) and different sleep traits and overall sleep pattern interact in the development of Parkinson’s disease (PD) remain unknown. Objective To prospectively investigate the joint associations of PA and sleep pattern with risk of PD. Methods Included were…
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Artikel Jurnal
Triglyceride-rich lipoproteins cholesterol, 10-years atherosclerotic cardiovascular disease risk, and risk of myocardial infarction and ischemic stroke
Triglyceride-rich lipoproteins cholesterol (TRLs-C) has been associated with atherosclerotic cardiovascular disease (ASCVD), even among individuals with low-density lipoprotein cholesterol in the targeted range. We assessed the associations of TRLs-C with myocardial infarction (MI) and ischemic…
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Association of regular aerobic exercises and neuromuscular junction variants with incidence of frailty: an analysis of the Chinese Longitudinal Health and Longevity Survey
Abstract Background Candidate genes of neuromuscular junction (NMJ) pathway increased risk of frailty, but the extent and whether can be offset by exercises was unclear. The aim of this study was to investigate the association between aerobic exercises and incident frailty regardless of NMJ…
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Artikel Jurnal
Cumulative remnant cholesterol and major adverse cardiovascular events among adults with type 2 diabetes
Background: Individuals with type 2 diabetes are prone to dyslipidemia. The relationship of cumulative exposure to elevated remnant cholesterol (RC) with major adverse cardiovascular events (MACEs) remains unclear for individuals with type 2 diabetes, especially for those with intensive…
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Artikel Jurnal
Associations Between High-Sensitivity C-Reactive Protein and All-Cause Mortality Among Oldest-Old in Chinese Longevity Areas: A Community-Based Cohort Study
BackgroundThe association between high-sensitivity C-reactive protein (hsCRP) levels and all-cause mortality for the oldest-old (aged 80 years or older) remains unclear. We aimed to investigate the associations between hsCRP concentrations and the risks of all-cause mortality, and further identify…
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Artikel Jurnal
Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis
Abstract Background Risk-adapted colorectal cancer (CRC) screening has the potential to balance effectiveness with resource demands, yet evidence comparing it with established methods remains limited. This study aims to compare outcomes of risk-adapted CRC screening with colonoscopy and fecal…