80 hasil untuk "Amresh Kumar"
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PSYCHOSIS IN RELATION TO EPILEPSY - A CLINICAL MODEL OF NEURO - PSYCHIATRY
Psychosis occurring in epileptics has always been an area of research interest, particularly, because of possible link of mental illness, organic lesions, convulsive process and behavioural abnormlity, all occuring together in the same subject. Vast amount of investigation on this subject has been…
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Assigning new supergroups V and W to the Wolbachia diversity
Wolbachia are endosymbiotic and alphaproteobacteria that belong to the order Rickettsiales. They are known to infect half of the insect population and cause host manipulation, and have been categorized into 19 monophyletic lineages called supergroups. Recently, two strains, wCfeJ and wCfeT were…
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Insights into the evolution of Wolbachia supergroup through the lens of genomic variation, phylogenetic and recombination analysis
Wolbachia is an alpha-proteobacteria and endosymbiont, causing infection in arthropods as parasites and in nematodes as mutualists. Unraveling the evolution of Wolbachia supergroups is the most fascinating topic among the scientific community. In this quest, we analyzed 30 Wolbachia genomes that…
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Recombination in sarbecovirus lineage and mutations/insertions in spike protein are linked to the emergence and adaptation of SARS-CoV-2
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan city, China in December 2019 and thereafter its spillover across the world has created a global pandemic and public health crisis. Right after, there has been intense interest in understanding how the SARS-CoV-2…
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Brief Overview: Current Scenario of Rotavirus Infection, Vaccine Coverage, and Future Prospects
This article reviews the burden of rotavirus (RV) disease and the role, types, and coverage of RV vaccines (RVVs) in India as well as globally. Establishing the epidemiology and burden of RV disease became an early priority. In the world, diarrheal infections are the second greatest cause of death…
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Dengue outbreak update in India: 2022
Dengue is an emerging illness in India, where it is endemic in some areas and sometimes causes yearly epidemics. Each dengue outbreak starts with high death and morbidity, which has a significant socioeconomic impact. As of September 30, 2022, India had 63,280 dengue cases, according to information…
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Host-Pathogen protein-protein interactions reveal the key mechanisms behind the endosymbiotic association of Wolbachia with Brugia malayi
Wolbachia are gram-negative endosymbiotic bacteria residing in the nematode host Brugia malayi that causes lymphatic filariasis in humans. Wolbachia settle in the host environment for their survival, growth and reproduction by maintaining an obligate mutualism relationship. However, the mechanism…
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Stump beyond the uterus: An uncommon neoplasm of the broad ligament
Primary malignancy of the broad ligament is an exceptionally rare condition. Due to its rarity, data on its epidemiology, management, and prognosis remain limited. These tumors present histologically with features intermediate between benign leiomyomas and malignant leiomyosarcomas. We report the…
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Mesenteric cystic lymphangioma in an adult female: A rare case report
Mesenteric cystic lymphangiomas (MCLs) are rare benign tumors of lymphatic origin, typically encountered in pediatric populations and primarily in regions, such as the neck and axilla. Intra-abdominal presentations, especially in adults, are exceedingly uncommon and often pose a diagnostic dilemma…
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Determination of cavitation zone for cavitating waterjet machining using numerical simulation
Recent developments of non-traditional machining techniques, like cavitating waterjet machining (CWJM), have gained attention for their simple operation and environment friendliness with zero carbon footprints. Cavitating waterjet machining leverages the erosive power of cavity bubbles combined…
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Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco
Background: Smoking is considered the single highest risk factor for lung cancer and has been suggested to be associated with accelerated somatic mutations in respiratory mucosa that lead to the development of lung cancer. MicroRNAs serve as modulators in smoking-induced mRNA gene expression…
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Healthcare workers’ perceptions and acceptance for COVID-19 vaccine for their children aged
BACKGROUND: The coronavirus disease 2019 (COVID-19) vaccination program among adults in India is one of the highly successful vaccination drives globally, but the acceptance of the COVID-19 vaccine among parents for their children is largely unknown. As parents are primary decision-makers for their…
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A Study of Unusual Pacemaker Infection by Mycobacterium Tuberculosis in Indian Patients
Background: The expanding clinical indications of cardiac rhythm management have led to an increased use of pacemaker implantation which is associated with increased incidence of pacemaker infections. Staphylococcus aureus and epidermidis account for the vast majority of pacemaker infections…
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Epidemiology of multi-drug-resistant tuberculosis in Northern India
India is the world's second most populous country, accounting for a quarter of the world's annual incidence of tuberculosis (TB). Every year around 2 million people develop TB in India and 300,000 die due to the TB. The emergence of drug-resistant-TB (DR-TB) has become a major public health concern…
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Global Impact of COVID-19 Pandemic on Antimicrobial Resistance: An Overview
Antimicrobial Resistance (AMR) is a condition which occurs, when pathogens evolve and no longer respond to antibiotics, making infections more difficult to treat and leads to death. Apart from the truth that antibiotics have increased the life expectancy of human, AMR is a serious threat. AMR is a…
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Adenocarcinoma arising in a retrorectal teratoma: A rare case report
Retrorectal teratomas are rare entities, particularly in adult men. We report a unique case involving a 25-year-old man who presented with lower abdominal distension and persistent constipation over 3 months. Per rectal examination revealed an extraluminal mass compressing the rectal mucosa…
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Anticancer Activity of the Amide-Imidazole Compound on Cancer Cell Lines: An In-Vitro Study
Introduction: The leading cause of morbidity and mortality in the world is cancer. Promising anti-cancer compounds include small heterocyclic chemicals. In many malignancies, cancer cells' resistance to therapy leads the recurrence and mortality after treatment. Drug resistance that develops during…
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The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India
BACKGROUND: The outcome of first episode schizophrenia has several determinants. Socioecological factors, particularly living conditions, migration, community and culture, not only affect the level of risk but also the outcome. Mega cities around the world show a unique socioecological condition…
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Effect of Percutaneous Mitral Balloon Commissurotomy on Sympatho-vagal Balance in Patients with Mitral Stenosis: A Prospective Cohort Study
INTRODUCTION: Mitral stenosis (MS) remains a significant cardiovascular burden, particularly in developing nations, where rheumatic heart disease is a major contributor. Percutaneous mitral balloon commissurotomy (PMBC) is a widely used intervention to improve hemodynamic and alleviate symptoms in…