46 hasil untuk "Athanasios Zachariou"

The effect of extended release tolterodine used for overactive bladder treatment on female sexual function

Athanasios Zachariou; Maria Filiponi

International Brazilian Journal of Urology, Vol. 43 No. 4 · Inggris · DOAJ Scopus

ABSTRACT Introduction Overactive bladder (OAB) is a common condition, especially in middle aged women, requiring long term therapy with anticholinergics to maintain symptoms relief. The aim of the study was to determine the effect of tolterodine extended release (ER) used for OAB treatment on the…

Primary Neoplasms of the Seminal Vesicles: A Narrative Review of Carcinoma and the Rarer Non-Epithelial and Biphasic Tumours

Athanasios Zachariou; Grigorios Daligkaros; Maria Filiponi

Diagnostics, Vol. 16 No. 18 · 2026 · Inggris · DOAJ Scopus

Primary carcinoma of the seminal vesicle is an exceptionally rare genitourinary malignancy, with evidence limited largely to case reports and small retrospective series. Diagnosis requires exclusion of more common secondary involvement from prostate, bladder, or rectal carcinoma through integration…

Commentary on: “Human umbilical cord wharton's jelly-derived mesenchymal stem cell transplantation could improve diabetic intracavernosal pressure”

Fotios Dimitriadis; Vasileios Palapelas; Athanasios Zachariou dkk.

Asian Journal of Andrology, Vol. 24 No. 2 · 2022 · Inggris · DOAJ Scopus

Urethral diverticulum with stone formation in an adult male after hypospadias repair: A case presentation

Ioannis Giannakis; Aris Kaltsas; Atsushi Takenaka dkk.

Urology Case Reports, Vol. 51 · 2023 · Inggris · DOAJ Scopus

Long-term complications of hypospadias surgery can lead to urethral diverticula, causing issues like stone formation, incomplete voiding, and infections. We present a case: a 45-year-old male, who underwent two-stage penile hypospadias repair at age three, now experiencing lower urinary obstruction…

Transurethral resection of a bladder trigone leiomyoma: a rare case report

Athanasios Zachariou; Maria Filiponi; Fotios Dimitriadis dkk.

BMC Urology, Vol. 20 No. 1 · 2020 · Inggris · DOAJ Scopus

Abstract Background Bladder leiomyomas are rare and benign tumors of the bladder. They account for 0.43% of all bladder tumors, and only 250 cases have been reported in English literature. Based on the size and localization of the lesion, their symptoms vary considerably. Women seem to be more…

Predictive Value of Varicocele Grade and Histopathology in Simultaneous Varicocelectomy and Sperm Retrieval in Non-Obstructive Azoospermia: A Retrospective Cohort Study

Aris Kaltsas; Fotios Dimitriadis; Michael Chrisofos dkk.

Medicina, Vol. 60 No. 12 · 2024 · Inggris · DOAJ Scopus

Background and Objectives: Varicocele repair in men with non-obstructive azoospermia (NOA) remains a subject of debate due to inconsistent outcomes. This study aimed to evaluate the impact of microsurgical varicocelectomy on sperm recovery rates in men with NOA and to assess the role of varicocele…

Phosphodiesterase Type 5 Inhibitors in Male Reproduction: Molecular Mechanisms and Clinical Implications for Fertility Management

Aris Kaltsas; Fotios Dimitriadis; Athanasios Zachariou dkk.

Cells, Vol. 14 No. 2 · 2025 · Inggris · DOAJ Scopus

Phosphodiesterases, particularly the type 5 isoform (PDE5), have gained recognition as pivotal regulators of male reproductive physiology, exerting significant influence on testicular function, sperm maturation, and overall fertility potential. Over the past several decades, investigations have…

Empirical Treatments for Male Infertility: A Focus on Lifestyle Modifications and Medicines

Aris Kaltsas; Athanasios Zachariou; Fotios Dimitriadis dkk.

Diseases, Vol. 12 No. 9 · 2024 · Inggris · DOAJ Scopus

Background/Objectives: Male infertility is a prevalent issue impacting numerous couples worldwide. This review aims to evaluate the effectiveness of empirical therapies for male infertility, focusing on both lifestyle modifications and medical treatments. This study provides a comprehensive…

When Testosterone Fades: Leydig Cell Aging Shaped by Environmental Toxicants, Metabolic Dysfunction, and Testicular Niche Crosstalk

Aris Kaltsas; Fotios Dimitriadis; Athanasios Zachariou dkk.

Cells, Vol. 15 No. 2 · 2026 · Inggris · DOAJ Scopus

Declining Leydig cell steroidogenesis contributes to late-onset hypogonadism and to age-associated impairment of male reproductive health. Determinants of dysfunction extend beyond chronological aging. This review synthesizes recent experimental and translational evidence on cellular and molecular…

Recent Advances in the Diagnosis and Management of Retrograde Ejaculation: A Narrative Review

Charalampos Konstantinidis; Athanasios Zachariou; Evangelini Evgeni dkk.

Diagnostics, Vol. 15 No. 6 · 2025 · Inggris · DOAJ Scopus

Retrograde ejaculation (RE) is a condition where the forward expulsion of seminal fluid is impaired, leading to infertility and psychological distress in affected individuals. This narrative review examines the etiology, pathophysiology, diagnosis, and management of RE, emphasizing its impact on…

Evaluating the Impact of Benign Prostatic Hyperplasia Surgical Treatments on Sexual Health

Aris Kaltsas; Zisis Kratiras; Athanasios Zachariou dkk.

Biomedicines, Vol. 12 No. 1 · 2024 · Inggris · DOAJ Scopus

Benign prostatic hyperplasia (BPH), a prevalent condition in older men, is often managed through various surgical interventions. This narrative review aims to explore the impact of these surgical treatments on sexual function, a critical aspect of patient quality of life often overlooked in BPH…

Paternal Contributions to Recurrent Pregnancy Loss: Mechanisms, Biomarkers, and Therapeutic Approaches

Aris Kaltsas; Athanasios Zikopoulos; Vladimir Kojovic dkk.

Medicina, Vol. 60 No. 12 · 2024 · Inggris · DOAJ Scopus

Background and Objectives: Recurrent pregnancy loss (RPL) affects numerous couples worldwide and has traditionally been attributed mainly to maternal factors. However, recent evidence highlights significant paternal influences on pregnancy viability and outcomes. This review aims to comprehensively…

Reproductive Health in Women with Major β-Thalassemia: Evaluating Ovarian Reserve and Endocrine Complications

Vasileios Tsilionis; Efthalia Moustakli; Stefanos Dafopoulos dkk.

Metabolites, Vol. 14 No. 12 · 2024 · Inggris · DOAJ Scopus

Thalassemia is an autosomal recessive hereditary chronic hemolytic anemia characterized by a partial or complete deficiency in the synthesis of alpha- or beta-globin chains, which are essential components of adult hemoglobin. Mutations in the globin genes lead to the production of unstable globin…

Phospholipase Cζ, the Molecular Spark of Fertilization and Male Infertility: Insights from Bench to Bedside

Aris Kaltsas; Maria-Anna Kyrgiafini; Zissis Mamuris dkk.

Medicina, Vol. 61 No. 6 · 2025 · Inggris · DOAJ Scopus

Phospholipase C zeta (PLCζ) has emerged as a pivotal sperm-specific factor responsible for triggering oocyte activation, a process essential for successful fertilization and early embryogenesis. A narrative review was conducted to examine the molecular architecture and biochemical features of PLCζ…

Dietary and Lifestyle Interventions to Mitigate Oxidative Stress in Male and Female Fertility: Practical Insights for Infertility Management—A Narrative Review

Efthalia Moustakli; Athanasios Zikopoulos; Periklis Katopodis dkk.

Metabolites, Vol. 15 No. 6 · 2025 · Inggris · DOAJ Scopus

Background/Objectives: Infertility in both men and women can be significantly influenced by oxidative stress (OS), which occurs due to an imbalance between reactive oxygen species (ROS) and the body’s antioxidant defenses. In women, OS disrupts oocyte maturation, implantation, and the viability of…

Correction to: Transvaginal closure of urinary bladder opening and Mitrofanof technique in a neurologically impaired female with chronic indwelling catheter: a case presentation

Athanasios Zachariou; Minas Paschopoulos; Aris Kaltsas dkk.

BMC Urology, Vol. 22 No. 1 · 2022 · Inggris · DOAJ Scopus

Platelet-Rich Plasma (PRP) in Reproductive Medicine: A Critical Review of PRP Therapy in Low-Reserve and Premature Ovarian Insufficiency

Efthalia Moustakli; Anastasios Potiris; Athanasios Zikopoulos dkk.

Biomedicines, Vol. 13 No. 5 · 2025 · Inggris · DOAJ Scopus

Background: Intraovarian platelet-rich plasma (PRP) has emerged as a novel intervention at the intersection of reproductive medicine and regenerative biology. As women with diminished ovarian reserve (DOR), poor response to stimulation, or premature ovarian insufficiency (POI) seek fertility…

The Silent Threat to Women’s Fertility: Uncovering the Devastating Effects of Oxidative Stress

Aris Kaltsas; Athanasios Zikopoulos; Efthalia Moustakli dkk.

Antioxidants, Vol. 12 No. 8 · 2023 · Inggris · DOAJ Scopus

Oxidative stress (OS), which arises through an imbalance between the formation of reactive oxygen species (ROS) and antioxidant defenses, plays a key role in the pathophysiology of female infertility, with the latter constituting just one of a number of diseases linked to OS as a potential cause…

Letrozole at the Crossroads of Efficacy and Fetal Safety in Ovulation Induction: A Narrative Review

Aris Kaltsas; Anna Efthimiou; Christos Roidos dkk.

Biomedicines, Vol. 13 No. 9 · 2025 · Inggris · DOAJ Scopus

Letrozole, a third-generation aromatase inhibitor initially developed for breast cancer, has become the preferred first-line agent for ovulation induction (OI), particularly in women with polycystic ovary syndrome (PCOS). This narrative review critically evaluates the efficacy, safety, and clinical…

The Impact of Endocrine Disruptors on the Female Genital Tract Microbiome: A Narrative Review

Efthalia Moustakli; Themos Grigoriadis; Anastasios Potiris dkk.

Life, Vol. 15 No. 8 · 2025 · Inggris · DOAJ Scopus

Background/Objectives: Endocrine disruptors (EDs) are xenobiotic chemicals that disrupt hormone signaling and homeostasis within the human body. Accumulative evidence proposes that EDs could affect systemic hormone balance and local microbial communities, including the female genital tract (FGT)…