46 hasil untuk "Burcin Ekser"
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Artikel Jurnal
Impact of artificial intelligence and virtual reality on the rehabilitation of general patients and patients undergoing surgical treatment
Physical rehabilitation aims to restore various bodily functions through professional monitoring and directed therapies, such as physical and occupational therapies. These rehabilitation methods can be time-consuming, costly, and even not accessible for patients. Effective rehabilitation is crucial…
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Artikel Jurnal
Liver Xenotransplantation: A Path to Clinical Reality
Liver xenotransplantation has emerged as a potential solution to the shortage of deceased human donor organs and is now becoming a reality due to recent developments in genetic engineering and immunosuppressive therapy. Early efforts using non-human primates and genetically modified pigs faced…
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Artikel Jurnal
The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation
Pig-to-human xenotransplantation offers a potential bridge to the growing disparity between patients with end-stage organ failure and graft availability. Early studies attempting to overcome cross-species barriers demonstrated robust humoral immune responses to discordant xenoantigens. Recent…
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Artikel Jurnal Teks lengkap
Comparison of porcine corneal decellularization methods and importance of preserving corneal limbus through decellularization
Background: The aim of this study is to compare the three previously applied, conventional porcine corneal decellularization methods and to demonstrate the importance of preserving the corneal limbus through decellularization. Methods: Fresh, wild-type (with or without) limbus porcine corneas were…
Juga tersedia di: DOAJ
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Artikel Jurnal Teks lengkap
Heme-Oxygenase and Kidney Transplantation: A Potential for Target Therapy?
Kidney transplantation is a well-established therapy for patients with end-stage renal disease. While a significant improvement of short-term results has been achieved in the short-term, similar results were not reported in the long-term. Heme-oxygenase (HO) is the rate-limiting enzyme in heme…
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Artikel Jurnal
Attachment and parental bond: impact on psychopathology, mental health and quality of life of hemodialysis patients: a cross-sectional study
Abstract Background Attachment theory represents a reference model for understanding better how pre-existing personality factors can influence the coping with some chronic conditions. The onset of a chronic disease can represent a "threat" to the relationships between the subject and parental…
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Artikel Jurnal
Current Barriers to Clinical Liver Xenotransplantation
Preclinical trials of pig-to-nonhuman primate liver xenotransplantation have recently achieved longer survival times. However, life-threatening thrombocytopenia and coagulation dysregulation continue to limit preclinical liver xenograft survival times to less than one month despite various genetic…
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Artikel Jurnal
Mental health, COVID-19 burden and quality of life of kidney transplant recipients two years after the COVID-19 pandemic
IntroductionFew studies have evaluated the psychological distress of COVID-19 in kidney transplantation and the psychological impact that the COVID-19 pandemic has had on kidney transplant recipients is not yet well understood. The present study aimed to investigate the change in symptom burden and…
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Artikel Jurnal
Endothelin Receptor-A Inhibition Decreases Ductular Reaction, Liver Fibrosis, and Angiogenesis in a Model of CholangitisSummary
Background & Aims: Primary sclerosing cholangitis (PSC) leads to ductular reaction and fibrosis and is complicated by vascular dysfunction. Cholangiocyte and endothelial cell crosstalk modulates their proliferation in cholestatic models. Endothelin (ET)-1 and ET-2 bind to their receptor, ET-A, and…
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Artikel Jurnal
Strategies to induce natural killer cell tolerance in xenotransplantation
Eliminating major xenoantigens in pig cells has drastically reduced human antibody-mediated hyperacute xenograft rejection (HXR). Despite these advancements, acute xenograft rejection (AXR) remains one of the major obstacles to clinical xenotransplantation, mediated by innate immune cells…
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Artikel Jurnal Teks lengkap
Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease
Fatty liver diseases, such as non-alcoholic fatty liver disease (NAFLD), are global health disparities, particularly in the United States, as a result of cultural eating habits and lifestyle. Pathological studies on NAFLD have been mostly focused on hepatocytes and other inflammatory cell types…