13 hasil untuk "Ching-Chih Lin"

Text-Mining and Digital Humanities Analysis of “Eye-Opening” Consecration Ritual of Contemporary Yanling Daoist Altar of Tainan

Ching-Chih Lin

Tūzī yǔ dàng’àn xuékān, Vol. 12 No. 2 · 2020 · Tionghoa · DOAJ

This article uses Digital Humanities methods and technologies, Text mining and GIS (geographic information system) to explore the ritual texts of the Deity “Eye-Opening” Consecration Ritual of Daoist Wu Zhengxian at the Yanling Daoist Altar in Tainan. The author uses the Python data extraction…

Metabolomic Analysis Demonstrates the Impacts of Polyketide Synthases PKS14 and PKS15 on the Production of Beauvericins, Bassianolide, Enniatin A, and Ferricrocin in Entomopathogen Beauveria bassiana

Wachiraporn Toopaang; Kullyanee Panyawicha; Chettida Srisuksam dkk.

Metabolites, Vol. 13 No. 3 · 2023 · Inggris · DOAJ Scopus

Beauveria bassiana is a globally distributed entomopathogenic fungus that produces various secondary metabolites to support its pathogenesis in insects. Two polyketide synthase genes, pks14 and pks15, are highly conserved in entomopathogenic fungi and are important for insect virulence. However…

Significant down-regulation of growth hormone receptor expression revealed as a new unfavorable prognos- tic factor in hepatitis C virus-related hepatocellular carcinoma

Ching-Chih Lin; Ta-Wei Liu; Ming-Lun Yeh dkk.

Clinical and Molecular Hepatology, Vol. 27 No. 2 · 2021 · Inggris · DOAJ Scopus

Background/Aims Growth hormone (GH) is the main regulator of somatic growth, metabolism, and gender dimorphism in the liver. GH receptor (GHR) signaling in cancer is derived from a large body of evidence, although the GHR signaling pathway involved in the prognosis of hepatocellular carcinoma (HCC)…

GSK3beta-Mediated Drp1 Phosphorylation Induced Elongated Mitochondrial Morphology against Oxidative Stress

Chia-Hua Chou; Ching-Chih Lin; Ming-Chang Yang dkk.

PLoS ONE, Vol. 7 No. 11 · 2012 · Inggris · PLOS Scopus

Multiple phosphorylation sites of Drp1 have been characterized for their functional importance. However, the functional consequence of GSK3beta-mediated phosphorylation of Drp1 remains unclear. In this report, we pinpointed 11 Serine/Threonine sites spanning from residue 634∼736 of the GED domain…

Juga tersedia di: DOAJ

Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors

Ching-Chih Lin; Sin Yong Hoo; Li-Ting Ma dkk.

Communications Biology, Vol. 5 No. 1 · 2022 · Inggris · DOAJ Scopus

In a multi-omics analysis, bacterial polyynes are found to act as antifungal agents by inhibiting the Candida albicans polyyne resistance gene ERG10, the homolog of MasL encoding acetyl-CoA acetyltransferase.

Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment

Chung-Feng Huang; Cing-Yi Huang; Ming-Lun Yeh dkk.

EBioMedicine, Vol. 15 No. C · 2017 · Inggris · DOAJ Scopus

Background/aims: The genome-wide association study has shown that MHC class I chain-related A (MICA) genetic variants were associated with hepatitis C virus (HCC) related hepatocellular carcinoma. The impact of the genetic variants and its serum levels on post-treatment cohort is elusive. Methods…

Corrigendum to “Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment” [EBioMedicine 15 (2017) 81–89]

Chung-Feng Huang; Ching-I Huang; Ming-Lun Yeh dkk.

EBioMedicine, Vol. 17 No. C · 2017 · Inggris · DOAJ Scopus

Identification of treatment-experienced hepatitis C patients with poor cost-effectiveness of pegylated interferon plus ribavirin from a real-world cohort

Ta-Wei Liu; Pei-Chien Tsai; Ching-I Huang dkk.

Journal of the Formosan Medical Association, Vol. 117 No. 1 · 2018 · Inggris · DOAJ Scopus

Pegylated interferon (PegIFN) plus ribavirin (RBV) combination therapy has been the standard of care since 2002. Although a better viral response has been achieved among chronic hepatitis C (CHC) patients in Taiwan, approximately 25% of hepatitis C virus (HCV) genotype 1 (G1) patients and 15% of G2…

Role of hepatitis D virus infection in development of hepatocellular carcinoma among chronic hepatitis B patients treated with nucleotide/nucleoside analogues

Tyng-Yuan Jang; Yu-Ju Wei; Ta-Wei Liu dkk.

Scientific Reports, Vol. 11 No. 1 · 2021 · Inggris · DOAJ Scopus

Abstract Hepatitis D virus (HDV) infection increases the risk of hepatocellular carcinoma (HCC) in the natural course of chronic hepatitis B (CHB) patients. Its role in patients treated with nucleotide/nucleoside analogues (NAs) is unclear. We aimed to study the role of hepatitis D in the…

Role of hepatitis D virus in persistent alanine aminotransferase abnormality among chronic hepatitis B patients treated with nucleotide/nucleoside analogues

Tyng-Yuan Jang; Yu-Ju Wei; Ming-Lun Yeh dkk.

Journal of the Formosan Medical Association, Vol. 120 No. 1 · 2021 · Inggris · DOAJ Scopus

Background: The biochemical response is a crucial indicator of prognosis in chronic hepatitis B (CHB) patients treated with nucleotide/nucleoside analogues (NAs). The impact of hepatitis D virus (HDV) infection on alanine aminotransferase normalization is elusive. Methods: The longitudinal study…

Regorafenib for Taiwanese patients with unresectable hepatocellular carcinoma after sorafenib failure: Impact of alpha‐fetoprotein levels

Po‐Yao Hsu; Tzu‐Sheng Cheng; Shih‐Chang Chuang dkk.

Cancer Medicine, Vol. 11 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Background and Aims Regorafenib has demonstrated its survival benefit for unresectable hepatocellular carcinoma (uHCC) patients in a phase III clinical trial. We aimed to assess the efficacy and tolerability of regorafenib and the predictors of treatment outcomes in Taiwanese patients…

Changing epidemiology and viral interplay of hepatitis B, C and D among injecting drug user-dominant prisoners in Taiwan

Ming-Ying Lu; Chun-Ting Chen; Yu-Lueng Shih dkk.

Scientific Reports, Vol. 11 No. 1 · 2021 · Inggris · DOAJ Scopus

Abstract The spreading of viral hepatitis among injecting drug users (IDU) is an emerging public health concern. This study explored the prevalence and the risks of hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HDV) among IDU-dominant prisoners in Taiwan. HBV surface…