32 hasil untuk "Fabio Cumbo"
Menampilkan 1–20 · 0,49 detik · RSS
-
Artikel Jurnal
GMS – Gammadiae Management System: cataloguing and interpretation project of the so-called gammadiae starting from the iconographic evidences in the Roman catacombs
In the Early Christian catacombs of Rome, the use of the so-called gammadiae was pretty common. Unfortunately, at the daily state of the art, the comprehension of these symbols is still object of discussion for the international research community. In this paper we present the Gammadiae Management…
-
Artikel Jurnal Teks lengkap
Hyperdimensional computing in biomedical sciences: a brief review
Hyperdimensional computing (HDC, also known as vector-symbolic architectures—VSA) is an emerging computational paradigm that relies on dealing with vectors in a high-dimensional space to represent and combine every kind of information. It finds applications in a wide array of fields including…
-
Artikel Jurnal Teks lengkap
Ten quick tips for avoiding pitfalls in multi-omics data integration analyses
Data are the most important elements of bioinformatics: Computational analysis of bioinformatics data, in fact, can help researchers infer new knowledge about biology, chemistry, biophysics, and sometimes even medicine, influencing treatments and therapies for patients. Bioinformatics and…
Juga tersedia di: DOAJ
-
Artikel Jurnal Teks lengkap
A Brain-Inspired Hyperdimensional Computing Approach for Classifying Massive DNA Methylation Data of Cancer
The recent advancements in cancer genomics have put under the spotlight DNA methylation, a genetic modification that regulates the functioning of the genome and whose modifications have an important role in tumorigenesis and tumor-suppression. Because of the high dimensionality and the enormous…
-
Artikel Jurnal Teks lengkap
Designing vector-symbolic architectures for biomedical applications: ten tips and common pitfalls
Vector-symbolic architectures (VSAs) provide a powerful, brain-inspired framework for representing and manipulating complex data across the biomedical sciences. By mapping heterogeneous information, from genomic sequences and molecular structures to clinical records and medical images, into a…
-
Artikel Jurnal Teks lengkap
GIANT: A Cytoscape Plugin for Modular Networks
Network analysis provides deep insight into real complex systems. Revealing the link between topological and functional role of network elements can be crucial to understand the mechanisms underlying the system. Here we propose a Cytoscape plugin (GIANT) to perform network clustering and…
Juga tersedia di: DOAJ
-
Artikel Jurnal
A novel Vector-Symbolic Architecture for graph encoding and its application to viral pangenome-based species classification
Abstract Viral species classification is crucial for understanding viral evolution, epidemiology, and developing effective diagnostics and treatments. Traditional methods often rely on sequence similarity, which can be challenging for rapidly evolving viruses. Pangenomes, offering a comprehensive…
-
Artikel Jurnal Teks lengkap
OpenGDC: Unifying, Modeling, Integrating Cancer Genomic Data and Clinical Metadata
Next Generation Sequencing technologies have produced a substantial increase of publicly available genomic data and related clinical/biospecimen information. New models and methods to easily access, integrate and search them effectively are needed. An effort was made by the Genomic Data Commons…
-
Artikel Jurnal Teks lengkap
Large-scale genome-wide analysis links lactic acid bacteria from food with the gut microbiome
Lactic acid bacteria (LAB) are fundamental in the production of fermented foods and several strains are regarded as probiotics. Large quantities of live LAB are consumed within fermented foods, but it is not yet known to what extent the LAB we ingest become members of the gut microbiome. By…
Juga tersedia di: DOAJ
-
Artikel Jurnal
Population-level impacts of antibiotic usage on the human gut microbiome
Here, the authors study the population-level impact of antimicrobial resistance genes (ARGs). By analyzing 8972 metagenomes and 3,096 gut microbiomes from healthy individuals not taking antibiotics, they demonstrate significant correlations between both the total ARG abundance and diversity and per…
-
Artikel Jurnal
Microbial genomes from non-human primate gut metagenomes expand the primate-associated bacterial tree of life with over 1000 novel species
Abstract Background Humans have coevolved with microbial communities to establish a mutually advantageous relationship that is still poorly characterized and can provide a better understanding of the human microbiome. Comparative metagenomic analysis of human and non-human primate (NHP) microbiomes…
-
Artikel Jurnal Teks lengkap
Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0
Microbial genomes are available at an ever-increasing pace, as cultivation and sequencing become cheaper and obtaining metagenome-assembled genomes (MAGs) becomes more effective. Phylogenetic placement methods to contextualize hundreds of thousands of genomes must thus be efficiently scalable and…
-
Artikel Jurnal
Neuroblastoma is associated with alterations in gut microbiome composition subsequent to maternal microbial seedingResearch in context
Summary: Background: Neuroblastoma is the most frequent extracranial solid tumour in children, accounting for ∼15% of deaths due to cancer in childhood. The most common clinical presentation are abdominal tumours. An altered gut microbiome composition has been linked to multiple cancer types, and…
-
Artikel Jurnal
An ontology-based approach for modelling and querying Alzheimer’s disease data
Abstract Background The recent advances in biotechnology and computer science have led to an ever-increasing availability of public biomedical data distributed in large databases worldwide. However, these data collections are far from being “standardized” so to be harmonized or even integrated…
-
Artikel Jurnal Teks lengkap
Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases
Fecal microbiota transplantation (FMT) is highly effective against recurrent Clostridioides difficile infection and is considered a promising treatment for other microbiome-related disorders, but a comprehensive understanding of microbial engraftment dynamics is lacking, which prevents informed…