58 hasil untuk "Indra Vythilingam"
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Artikel Jurnal
NEW PROACTIVE PARADIGM FOR DENGUE SURVEILLANCE USING GOD TRAPS AND NS1 KITS
Dengue continues to be a major public health problem in many parts of the world. Vector control is the hallmark of dengue control programme in most countries in Southeast Asia. However, it is known that the current program lacks sensitivity and proactivity. It is also known that asymptomatic people…
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Artikel Jurnal
Modified technique of Wolbachia removal from Malaysian Aedes albopictus
Objective: To develop an artificial and modified Wolbachia removal technique using tetracycline from naturally Wolbachia infected Aedes albopictus (Ae. albopictus) so as to be able to produce generations of Wolbachia free offsprings. Methods: In this study, seven different tetracycline treatment…
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Artikel Jurnal Teks lengkap
Phylogenetic analysis of simian Plasmodium spp. infecting Anopheles balabacensis Baisas in Sabah, Malaysia
Background: Anopheles balabacensis of the Leucospyrus group has been confirmed as the primary knowlesi malaria vector in Sabah, Malaysian Borneo for some time now. Presently, knowlesi malaria is the only zoonotic simian malaria in Malaysia with a high prevalence recorded in the states of Sabah and…
Juga tersedia di: DOAJ
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Artikel Jurnal
Plasmodium cynomolgi: potential emergence of new zoonotic malaria in Southeast Asia
Abstract The reported cases of Plasmodium cynomolgi in Southeast Asia pose a significant public health concern. Sporadic reports of human Plasmodium cynomolgi infections have increased in the past few years, raising attention regarding its potential impact on human populations. Further compounding…
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Artikel Jurnal
Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand
Abstract Background The C-terminal 42 kDa domain of Plasmodium knowlesi merozoite surface protein 1 (PkMSP1) is a potential asexual blood-stage vaccine candidate, however, only a limited number of clinical isolates have been analysed from Malaysia and no inter-country comparative diversity study…
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Artikel Jurnal Teks lengkap
Human exposure to zoonotic malaria vectors in village, farm and forest habitats in Sabah, Malaysian Borneo
The zoonotic malaria parasite, Plasmodium knowlesi, is now a substantial public health problem in Malaysian Borneo. Current understanding of P. knowlesi vector bionomics and ecology in Sabah comes from a few studies near the epicentre of human cases in one district, Kudat. These have incriminated…
Juga tersedia di: DOAJ
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Artikel Jurnal Teks lengkap
Plasmodium knowlesi infecting humans in Southeast Asia: What’s next?
Plasmodium knowlesi, a simian malaria parasite, has been in the limelight since a large focus of human P. knowlesi infection was reported from Sarawak (Malaysian Borneo) in 2004. Although this infection is transmitted across Southeast Asia, the largest number of cases has been reported from…
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Artikel Jurnal
Gravid oviposition sticky trap and dengue non-structural 1 antigen test for early surveillance of dengue in multi-storey dwellings: study protocol of a cluster randomized controlled trial
Abstract Background Dengue is a global disease, transmitted by the Aedes vectors. In 2018, there were 80 615 dengue cases with 147 deaths in Malaysia. Currently, the nationwide surveillance programs are dependent on Aedes larval surveys and notifications of lab-confirmed human infections. The…
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Artikel Jurnal
Effect of different habitat types on abundance and biting times of Anopheles balabacensis Baisas (Diptera: Culicidae) in Kudat district of Sabah, Malaysia
Abstract Background We investigated the effect of five common habitat types on the diversity and abundance of Anopheles spp. and on the biting rate and time of Anopheles balabacensis (currently the only known vector for Plasmodium knowlesi in Sabah) at Paradason village, Kudat, Sabah. The habitats…
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Prevalence of simian malaria parasites in macaques of Singapore
Plasmodium knowlesi is a simian malaria parasite currently recognized as the fifth causative agent of human malaria. Recently, naturally acquired P. cynomolgi infection in humans was also detected in Southeast Asia. The main reservoir of both parasites is the long-tailed and pig-tailed macaques…
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Artikel Jurnal
New Paradigms for Virus Detection, Surveillance and Control of Zika Virus Vectors in the Settings of Southeast Asia
Zika virus (ZIKV) has now become a global public health concern. The vectors for ZIKV are Aedes aegypti and Aedes albopictus. Both these mosquitoes are predominant in Southeast Asia and are also responsible for the spread of other arboviral diseases like dengue virus (DENV) and chikungunya virus…
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Artikel Jurnal
Insecticide resistance and its underlying mechanisms in field populations of Aedes aegypti adults (Diptera: Culicidae) in Singapore
Abstract Background In Singapore, dose–response bioassays of Aedes aegypti (L.) adults have been conducted, but the mechanisms underlying resistance to insecticides remain unclear. In this study, we evaluated insecticide resistance and its underlying mechanism in field populations of Ae. aegypti…
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Artikel Jurnal
Is there evidence of sustained human-mosquito-human transmission of the zoonotic malaria Plasmodium knowlesi? A systematic literature review
Abstract Background The zoonotic malaria parasite Plasmodium knowlesi has emerged across Southeast Asia and is now the main cause of malaria in humans in Malaysia. A critical priority for P. knowlesi surveillance and control is understanding whether transmission is entirely zoonotic or is also…
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High transmission efficiency of the simian malaria vectors and population expansion of their parasites Plasmodium cynomolgi and Plasmodium inui
Background: The elimination of malaria in Southeast Asia has become more challenging as a result of rising knowlesi malaria cases. In addition, naturally occurring human infections with other zoonotic simian malaria caused by Plasmodium cynomolgi and Plasmodium inui adds another level of complexity…
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Investigating the Contribution of Peri-domestic Transmission to Risk of Zoonotic Malaria Infection in Humans
Background: In recent years, the primate malaria Plasmodium knowlesi has emerged in human populations throughout South East Asia, with the largest hotspot being in Sabah, Malaysian Borneo. Control efforts are hindered by limited knowledge of where and when people get exposed to mosquito vectors. It…
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Artikel Jurnal
Comparison of microscopy and PCR for the detection of human Plasmodium species and Plasmodium knowlesi in southern Myanmar
Objectives: To determine the distribution of Plasmodium (P) species including Plasmodium knowlesi and to compare the specificity and sensitivity of microscopy with nested PCR in malaria diagnosis. Methods: The study was conducted in Kawthaung, southern Myanmar. Ninety clinically suspected malaria…
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Artikel Jurnal Teks lengkap
Correction: Pramasivan et al. Multiplex PCR Assay for the Identification of Four Species of the Anopheles Leucosphyrus Sub-Group in Malaysia. Insects 2022, 13, 195
In the original publication [...]