27 hasil untuk "Jakub Fiegler-Rudol"
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Artikel Jurnal
HPV among men – what knowledge we have in this field
The human papillomavirus (HPV) is a common sexually transmitted DNA virus. The resulting infection may be asymptomatic or manifest itself through benign symptoms such as warts, affecting the genitals and skin. It is a common etiological factor associated with various cancers, most notably cervical…
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Artikel Jurnal
Tick-borne encephalitis on the horizon – a call to action for Poland
Tick-borne encephalitis (TBE) is a viral infection of the central nervous system caused by viruses belonging to the family Flaviviridae. The disease manifests with a range of symptoms, including fever, dizziness, nausea, vomiting, and neurological complications, such as meningoencephalitis and…
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Laser Interventions for Intraoral Halitosis: A Systematic Review of Randomized Controlled Trials
Background: This systematic review evaluated the efficacy of laser therapies and antimicrobial photodynamic therapy (aPDT) for the treatment of intraoral halitosis by synthesizing randomized controlled trials. Methods: A comprehensive search of the PubMed, Embase, Scopus, and Cochrane Library…
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The Efficacy of Curcumin-Mediated Photodynamic Therapy in the Treatment of Oral Squamous Cell Carcinoma: A Systematic Review of In Vitro Studies
Curcumin-mediated photodynamic therapy (PDT) has emerged as a promising approach for targeting oral squamous cell carcinoma (OSCC), a malignancy with a rising incidence. This systematic review synthesizes evidence from in vitro studies evaluating the anticancer efficacy of curcumin as a…
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Er:YAG Laser Energy Optimization for Reducing Single-Species Microbial Growth on Agar Surfaces In Vitro
Background: Standardized Er:YAG laser settings for microbial reduction remain undefined, and existing studies rarely compare multiple species under identical conditions. This work aimed to characterize susceptibility across selected microorganisms using a controlled agar-based surface growth model…
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Antibacterial and Bactericidal Effects of the Er: YAG Laser on Oral Bacteria: A Systematic Review of Microbiological Evidence
Background: The Er:YAG laser has gained attention in dentistry for its potential to enhance microbial disinfection through targeted photothermal and photoacoustic mechanisms. Objective: This systematic review aimed to evaluate the antibacterial and bactericidal efficacy of Er:YAG laser therapy…
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Hypericin-Mediated Photodynamic Therapy for Head and Neck Cancers: A Systematic Review
Background: Conventional treatments for cancers of the head and neck region are often associated with high recurrence rates and impaired quality of life. Photodynamic therapy (PDT) has emerged as a promising alternative, leveraging photosensitizers such as hypericin to selectively target tumour…
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The Role of Photodynamic Therapy Mediated by Natural Photosensitisers in the Management of Peri-Implantitis: A Systematic Review
Background: Peri-implantitis, an inflammatory condition leading to progressive bone loss around dental implants, represents a significant challenge in modern implant dentistry. Conventional mechanical debridement and adjunctive antibiotics or antiseptics often fail to fully eradicate complex…
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Expanding the Therapeutic Profile of Topical Cannabidiol in Temporomandibular Disorders: Effects on Sleep Quality and Migraine Disability in Patients with Bruxism-Associated Muscle Pain
Background: Cannabidiol (CBD) has demonstrated potential as a therapeutic agent for muscle tension, pain, and sleep bruxism, yet its broader impact on comorbid conditions such as sleep disturbance and migraine disability remains underexplored. This study aimed to assess the effects of topical CBD…
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Artikel Jurnal
Novel approaches for oroantral communication closure: A literature review
Introduction: Oroantral communication (OAC) and oroantral fistula (OAF) are common complications of maxillary posterior tooth extraction. Although conventional flap techniques remain effective, they are associated with postoperative morbidity, anatomical alterations, and limitations in patients…
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Riboflavin-Mediated Photodynamic Therapy in Periodontology: A Systematic Review of Applications and Outcomes
Background: Riboflavin (vitamin B2) has emerged as a promising photosensitizer in photodynamic therapy (PDT) due to its strong absorption of blue light and favourable safety profile. This systematic review aims to evaluate the efficacy of riboflavin-mediated PDT in periodontology, specifically…
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Riboflavin- and Hypericin-Mediated Antimicrobial Photodynamic Therapy as Alternative Treatments for Oral Candidiasis: A Systematic Review
Background: Oral candidiasis, predominantly caused by Candida albicans, presents significant challenges in treatment due to increasing antifungal resistance and biofilm formation. Antimicrobial photodynamic therapy (aPDT) using natural photosensitizers like riboflavin and hypericin offers a…
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Analysis of the Uptake of Hypericin by Candida albicans Yeast Cells Using Fluorescence Methods and Comparison of the Dynamics of This Process over Time
Background: Hypericin is a natural photosensitizer with promising antifungal potential, but its uptake kinetics in Candida (C.) albicans are not well defined. Objective: To characterize the time-dependent uptake of hypericin by C. albicans in vitro using fluorescence microscopy and quantitative…
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Artikel Jurnal
Dose-dependent effects of Er:YAG laser on human fibroblast proliferation, cell death, and γH2AX DNA damage signaling
Introduction: The biological response of fibroblasts to Er:YAG laser irradiation is dose-dependent, yet the threshold between biologically tolerable and cytotoxic exposure remains insufficiently defined. The aim of the study is to evaluate dose-dependent effects of Er:YAG laser irradiation (80–180…
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How to Deal with Pulpitis: An Overview of New Approaches
Background: Traditional root canal therapy (RCT) effectively removes diseased or necrotic pulp tissue and replaces it with inorganic materials. Regenerative endodontics is an alternative to conventional RCT by using biologically based approaches to restore the pulp–dentin complex. This review…
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Artikel Jurnal
Artificial intelligence in pathology: from image analysis to clinical decision support
Artificial intelligence is transforming pathology by enhancing diagnostic precision and supporting clinical decision-making. Its application often involves digital imaging and machine learning to analyse whole slide imaging (WSI) data. AI algorithms can detect cellular abnormalities, classify…
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The Therapeutic Potential of Cannabidiol in the Management of Temporomandibular Disorders and Orofacial Pain
Background: Temporomandibular disorders (TMDs) are a group of conditions affecting the temporomandibular joint (TMJ) and associated muscles, leading to pain, restricted jaw movement, and impaired quality of life. Conventional treatments, including physical therapy, medications, and surgical…
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In Vitro Antifungal Efficacy of Blue-Light Photodynamic Therapy with Curcumin and Riboflavin Formulation Activated by 450 nm Diode Laser Against Candida albicans Biofilm on Titanium Implants
Background: Candida albicans is increasingly recognized in peri-implantitis due to its capacity to form resilient biofilms on implant surfaces, limiting treatment success. Antimicrobial photodynamic therapy (aPDT) may offer a non-invasive adjunct by leveraging photosensitizer activation to produce…
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Evaluation of the Disinfection Efficacy of Er-YAG Laser Light on Single-Species Candida Biofilms: Systematic Review
The relevance of the current study is to increase the resistance of fungal biofilms to traditional disinfection methods. The aim of the study was to determine how effectively Er:YAG laser light inhibits single-species Candida biofilms. The study involved a systematic review of 57 scientific…
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Enhancing Root Canal Disinfection with Er:YAG Laser: A Systematic Review
Background: The quest for minimally invasive disinfection in endodontics has led to using Erbium:Yttrium-Aluminum-Garnet (Er:YAG) lasers. Conventional approaches may leave bacterial reservoirs in complex canal anatomies. Er:YAG’s strong water absorption generates photoacoustic streaming, improving…