18 hasil untuk "Jen-Fu Yang"
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Artikel Jurnal Teks lengkap
A System for the Real-Time Detection of the U-Shaped Steel Bar Straightness on a Production Line
This study develops an algorithm and a system for steel straightness detection, which combines object detection, edge detection, line detection, clustering, stitching, and bending recognition. The algorithm detects the contour of U-shaped steel bars with widths of 100 mm, named U100, or 150 mm…
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Artikel Jurnal Teks lengkap
Survival and prognostic factors for patients with advanced hepatocellular carcinoma after stereotactic ablative radiotherapy
Objective: To evaluate the survival outcomes and prognostic factors of patients with advanced hepatocellular carcinoma (HCC) who underwent stereotactic ablative radiotherapy (SABR). Methods: This retrospective study evaluated patients with advanced HCC who underwent SABR between December 2007 and…
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Artikel Jurnal Teks lengkap
Lower Urinary Tract Infection and Subsequent Risk of Prostate Cancer: A Nationwide Population-Based Cohort Study
Purpose: We investigated whether lower urinary tract infection (LUTI), including cystitis or urethritis, is associated with an increased risk of developing prostate cancer (PCa), in a nationwide population-based cohort study. Methods: We identified 14,273 men newly diagnosed with LUTI (9347 with…
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Oral tegafur-uracil as metronomic therapy following intravenous FOLFOX for stage III colon cancer
The purpose of this study was to estimate the impact of metronomic therapy with oral tegafur-uracil (UFUR) following an intravenous FOLFOX regimen as surgical adjuvant chemotherapy on the overall survival (OS) and disease-free survival (DFS) of stage III colon cancer patients. From the…
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Stereotactic ablative radiotherapy versus conventionally fractionated radiotherapy in the treatment of hepatocellular carcinoma with portal vein invasion: a retrospective analysis
Abstract Background This study aimed to compare the clinical outcomes of stereotactic ablative radiotherapy (SABR) and conventionally fractionated radiotherapy (CFRT) in hepatocellular carcinoma (HCC) patients with portal vein invasion (PVI). Methods HCC patients with PVI treated with radiotherapy…
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Artikel Jurnal
Radiosensitivity index emerges as a potential biomarker for combined radiotherapy and immunotherapy
Abstract In the era of immunotherapy, there lacks of a reliable genomic predictor to identify optimal patient populations in combined radiotherapy and immunotherapy (CRI). The purpose of this study is to investigate whether genomic scores defining radiosensitivity are associated with immune…
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Gene-associated methylation status of ST14 as a predictor of survival and hormone receptor positivity in breast Cancer
Abstract Background Genomic profiles of specific gene sets have been established to guide personalized treatment and prognosis for patients with breast cancer (BC). However, epigenomic information has not yet been applied in a clinical setting. ST14 encodes matriptase, a proteinase that is widely…
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Pharmacokinetics and Safety Profile of SNS812, a First in Human Fully Modified siRNA Targeting Wide‐Spectrum SARS‐CoV‐2, in Healthy Subjects
ABSTRACT Severe acute respiratory syndrome caused by the coronavirus (SARS‐CoV‐2) in the COVID‐19 pandemic has highlighted the need for effective treatments, as rapid viral mutations complicate therapeutic development. SNS812, a fully modified inhaled siRNA that targets the conserved RNA‐dependent…
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Artikel Jurnal
Clinical outcome and pathologic correlation of stereotactic body radiation therapy as a bridge to transplantation for advanced hepatocellular carcinoma: a case series
Abstract Background Stereotactic body radiotherapy (SBRT) is an emerging modality for hepatocellular carcinoma (HCC). However, there is scant information about its safety and effectiveness in the neoadjuvant setting prior to liver transplantation (LT). We present the clinical outcome and pathologic…
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Artikel Jurnal Teks lengkap
Radiomics-Based Predictive Model of Radiation-Induced Liver Disease in Hepatocellular Carcinoma Patients Receiving Stereo-Tactic Body Radiotherapy
(1) Background: The application of stereotactic body radiation therapy (SBRT) in hepatocellular carcinoma (HCC) limited the risk of the radiation-induced liver disease (RILD) and we aimed to predict the occurrence of RILD more accurately. (2) Methods: 86 HCC patients were enrolled. We identified…
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Significant muscle loss after stereotactic body radiotherapy predicts worse survival in patients with hepatocellular carcinoma
Abstract The relationship between sarcopenia and treatment outcomes, especially in patients with hepatocellular carcinoma (HCC) undergoing stereotactic body radiotherapy (SBRT) has not been well-explored. This study aimed to investigate the effects of sarcopenia on the survival and toxicity after…
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Artikel Jurnal
Radiation-induced severe lymphopenia predicts distant metastasis in rectal cancer: dosimetric implications for immune-sparing radiotherapy
Abstract Background Lymphopenia is a frequent complication of pelvic radiotherapy and may impair systemic immune surveillance. This study aimed to evaluate the prognostic impact of acute severe lymphopenia (ASL) in rectal cancer and to identify dosimetric predictors relevant to immune-sparing…
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Development and Validation of a Nomogram for Patients with Nonmetastatic BCLC Stage C Hepatocellular Carcinoma after Stereotactic Body Radiotherapy
Background: Stereotactic body radiotherapy (SBRT) is an emerging treatment modality for hepatocellular carcinoma (HCC) with promising outcome. However, appropriate survival prediction models are scarce. This study aimed to develop a simple and clinically useful prognostic nomogram for patients with…
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Artikel Jurnal
Radiation dose escalation in locally advanced oesophageal cancer: a systematic review and hierarchical Bayesian meta-analysisResearch in context
Summary: Background: The impact of radiation dose escalation in locally advanced oesophageal cancer remains controversial. While higher doses may improve locoregional control, their effect on overall survival (OS) and progression-free survival (PFS) remains uncertain. The aim of this study was to…
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Artikel Jurnal
Safety and antiviral activity of inhaled siRNA SNS812 for treatment of mild-to-moderate COVID-19: a phase 2 randomized trial
Abstract Background SARS-CoV-2 remains a global health threat because ongoing viral evolution and immune evasion reduce the effectiveness of existing therapies. SNS812 is an inhaled small interfering RNA targeting a highly conserved region of the viral RNA-dependent RNA polymerase gene…