13 hasil untuk "Jiaming Yuan"
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Artikel Jurnal
A Sensitive Fluorescence Biosensor for Silver Ions (Ag+) Detection Based on C-Ag+-C Structure and Exonuclease III-Assisted Dual-Recycling Amplification
A C-Ag+-C structure-based fluorescence biosensor with novel combination design of exonuclease III (Exo III) dual-recycling amplification is proposed for the application of silver ions (Ag+) detection. Since oligo-1 involves C-C mismatches, the presence of Ag+ can be captured to form C-Ag+-C base…
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Artikel Jurnal
Hepatoid Adenocarcinoma of the Stomach: Current Perspectives and New Developments
Hepatoid adenocarcinoma of the stomach (HAS) is a rare malignant tumor, accounting for only 0.17–15% of gastric cancers. Patients are often diagnosed at an advanced disease stage, and their symptoms are similar to conventional gastric cancer (CGC) without specific clinical manifestation…
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Artikel Jurnal Teks lengkap
Effect of Surface Reinforcer on Compressive Strength and Microscopic Mechanism of Freeze–Thaw-Deteriorated Concrete
Due to the deterioration caused by repeated freeze–thaw cycles, concrete materials in cold regions often develop cracks, which have serious effects and challenge the durability of concrete-based structures. Therefore, it is worthwhile to repair and strengthen freeze–thaw-damaged concrete to extend…
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Artikel Jurnal Teks lengkap
Failure Mode and Mechanisms of Gneiss Open-Pit Slopes in Cold Regions—A Case Study of the 14 September 2023 Landslide at the Jinbao Mine in Xinjiang, China
Extensive high and steep open-pit slopes in gneiss are distributed in cold regions at high altitudes or high latitudes of China, such as Qinghai, Tibet, and Xinjiang, posing significant hazards to mine safety. Several recent slope failure incidents highlight the urgent need to study the failure…
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Artikel Jurnal
A recognition method for drainage patterns using a graph convolutional network
Drainage pattern recognition (DPR) is a classic and challenging problem in hydrographic system analysis, topographical knowledge mining, and map generalization. An outstanding issue for traditional DPR methods is that the rules used to extract patterns based on certain geometric measures are…
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Artikel Jurnal
Effect of hot isostatic pressing treatment on porosity reduction and mechanical properties enhancement of 316L stainless steel fabricated by binder jetting
In this work, a hot isostatic pressing (HIP) treatment was used to reduce the pores and improve the mechanical properties of binder jetting (BJ) fabricated 316L stainless steel. The relative density of the HIP treated samples sintered under vacuum, nitrogen, and argon atmospheres increased from…
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Artikel Jurnal
Catalytic Hydrogenolysis of Lignin over Chromium-containing Tannery Waste-derived Ru-based Catalyst
ObjectiveTo address the dual challenges of environmental pollution stemming from the leather industry and the sustainable biomass transformation, this study integrated the upcycling of industrial solid waste with advanced biorefinery processes. An efficient and low-cost lignin hydrogenolysis…
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Artikel Jurnal Teks lengkap
High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening
How to rapidly and accurately screen bioactive components from complex natural products remains a major challenge. In this study, a screening platform for pancreatic lipase (PL) inhibitors was established by combining magnetic beads-based ligand fishing and high-resolution bioassay profiling. This…
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Artikel Jurnal
Establishment of an at-line nanofractionation-based screening platform for rapid identification of influenza PAN/PAN I38T inhibitors from Artemisiae Argyi Folium
The N-terminal domain of influenza viral polymerase (PAN), a highly conserved region with critical catalytic function related to viral RNA replication and transcription, is considered as a very promising anti-influenza drug target. There is an urgent need for highly efficient and rapid screening…
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Artikel Jurnal
A Narrative Review of Circular RNAs in Brain Development and Diseases of Preterm Infants
Circular RNAs (circRNAs) generated by back-splicing are the vital class of non-coding RNAs (ncRNAs). Circular RNAs are highly abundant and stable in eukaryotes, and many of them are evolutionarily conserved. They are blessed with higher expression in mammalian brains and could take part in the…
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Artikel Jurnal
Integrating high-resolution bioassay profiling with affinity-based ligand fishing for unveiling galloylated derivatives as novel catechol-O-methyltransferase inhibitors in Paeonia lactiflora Pall.
Catechol-O-methyltransferase (COMT) inhibition is a critical therapeutic strategy for Parkinson's disease (PD), yet clinical inhibitors face limitations in bioavailability and hepatotoxicity, driving demand for novel natural scaffolds. In this study, we developed an integrated analytical platform…
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Artikel Jurnal
Electrochemical catalytic hydrogenation of guaiacol by collagen-based N-doped carbon supported PtRu catalyst
The reduction of biomass derived phenols by electrochemical catalysis is an ideal route toward sustainable biorefinery processes. Herein, we present a highly efficient and selective electrochemical catalytic hydrogenation (ECH) of guaiacol by using N-doped carbon supported PtRu catalyst (PtRu/NC)…
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Artikel Jurnal
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis
Inorganic arsenic compounds are environmental toxicants that are widely distributed in air, water, and food. B-cell lymphoma 2 (BCL-2) is an oncogene having anti-apoptotic function. In this study, we clarify that BCL-2, as a pro-apoptotic factor, participates in As2O3-induced apoptosis in BEAS-2B…