22 hasil untuk "Lars Libuda"
Menampilkan 1–20 · 0,87 detik · RSS
-
Artikel Jurnal
Food-based modification of LC-PUFA concentration in complementary food did not affect plasma vitamin E concentration in infants
Background: ω-3 Long-chain polyunsaturated fatty acids (ω-3 LC-PUFA) are essential for an optimal development of infants. An increased dietary intake of ω-3 PUFA may also be associated with a decrease in the vitamin E content in the blood of healthy infants because these fatty acids have more…
-
Artikel Jurnal
Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity
There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androgen receptor gene (AR), a variable number of CAG…
-
Artikel Jurnal
Suggestive Evidence for Causal Effect of Leptin Levels on Risk for Anorexia Nervosa: Results of a Mendelian Randomization Study
Genetic correlations suggest a coexisting genetic predisposition to both low leptin levels and risk for anorexia nervosa (AN). To investigate the causality and direction of these associations, we performed bidirectional two-sample Mendelian randomization (MR) analyses using data of the most recent…
-
Artikel Jurnal
Lack of Evidence for a Relationship Between the Hypothalamus-Pituitary-Adrenal and the Hypothalamus-Pituitary-Thyroid Axis in Adolescent Depression
In adults with major depressive disorder (MDD), a dysfunction between the hypothalamus-pituitary-adrenal (HPA) and the hypothalamus-pituitary-thyroid (HPT) axis has been shown, but the interaction of both axes has not yet been studied in adolescent major depressive disorder (MDD). Data from 273…
-
Artikel Jurnal
The Chinese Adolescent Cohort Study: Design, Implementation, and Major Findings
The importance of diet quality on children's growth is being increasingly recognized. The Chinese Adolescent Cohort (CAC) is a longitudinal cohort study to comprehensively investigate the health impacts of nutritional factors on child growth. From 2013 to 2018, 6,967 children aged 6–8 years have…
-
Artikel Jurnal Teks lengkap
The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown.
Young adults with a later chronotype are vulnerable for a discrepancy in sleep rhythm between work- and free days, called social jet lag (SJL). This study analysed (i) chronotype/SJL association with visceral fat/skeletal muscle mass, (ii) the attribution to physical activity behaviour, and (iii)…
-
Artikel Jurnal
The association between dairy intake in adolescents on inflammation and risk markers of type 2 diabetes during young adulthood: results of the DONALD study
Abstract Objective: The aim of this analysis was to investigate whether habitual intake of total dairy (TD) or different dairy types (liquid, solid, fermented, non-fermented, low-fat, high-fat, low-sugar and high-sugar dairy) during adolescence is associated with biomarkers of low-grade…
-
Artikel Jurnal
Clinical Trials Required to Assess Potential Benefits and Side Effects of Treatment of Patients With Anorexia Nervosa With Recombinant Human Leptin
The core phenotype of anorexia nervosa (AN) comprises the age and stage dependent intertwining of both its primary and secondary (i.e., starvation induced) somatic and mental symptoms. Hypoleptinemia acts as a key trigger for the adaptation to starvation by affecting diverse brain regions including…
-
Artikel Jurnal
Adherence to dietary recommendations according to the General Dietary Behavior Inventory (GDBI) and its association with bioelectrical impedance analysis (BIA) parameters among young, healthy and normal weight women
Abstract Background The General Dietary Behavior Inventory (GDBI) is a low effort instrument with only 16 items to assess the general dietary behavior based on the dietary recommendations of the World Health Organization and the German Nutrition Society. In an online survey with a convenience…
-
Artikel Jurnal Teks lengkap
Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents
Background: Evidence has accumulated for the association between low vitamin D serum concentrations and mental health disorders in both children and adults. We performed a cross-sectional analysis in a population-based sample of children and adolescents to detect associations between 25(OH)-vitamin…
Juga tersedia di: DOAJ
-
Artikel Jurnal
Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial: study protocol
Abstract Background Depression is a significant health and economic burden worldwide affecting not only adults but also children and adolescents. Current treatment options for this group are scarce and show moderate effect sizes. There is emerging evidence that dietary patterns and specific…
-
Artikel Jurnal
The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study
Anthropometric traits and mental disorders or traits are known to be associated clinically and to show genetic overlap. We aimed to identify genetic variants with relevance for mental disorders/traits and either (i) body mass index (or obesity), (ii) body composition, (and/or) (iii) body fat…
-
Artikel Jurnal
The adrenal steroid profile in adolescent depression: a valuable bio-readout?
Abstract There is preliminary evidence that adrenal steroids other than cortisol may be valuable biomarkers for major depressive disorder (MDD). So far, studies have been conducted in adults only, and conclusions are limited, mainly due to small sample sizes. Therefore, the present study assessed…
-
Artikel Jurnal Teks lengkap
Evaluation of Metabolic Profiles of Patients with Anorexia Nervosa at Inpatient Admission, Short- and Long-Term Weight Regain—Descriptive and Pattern Analysis
Acute anorexia nervosa (AN) constitutes an extreme physiological state. We aimed to detect state related metabolic alterations during inpatient admission and upon short- and long-term weight regain. In addition, we tested the hypothesis that metabolite concentrations adapt to those of healthy…
-
Artikel Jurnal
Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?– Implications from experimental measurements in young, healthy, and normal weight women
Abstract Anorexia nervosa (AN) is a severe mental disorder, and patients with AN are characterized by a low body weight and a fear of gaining weight. Restoration of body weight to the normal range is one major treatment aim, which can be a challenging process for the patients. Hence, as a…
-
Artikel Jurnal
Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania
Abstract Background In Sub-Saharan African countries, rapid urbanization and increasing socio-economic status are associated with a transition to decreased physical activity (PA). A more sedentary lifestyle is linked to increased body fat leading to increments in leptin levels. Since rodent and…
-
Artikel Jurnal
Exploring serum biomarkers in paediatric psychiatry: the impact of NfL and GFAP
Abstract Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (GFAP) are biomarkers of neuroaxonal and astrocytic damage but remain understudied in adolescent psychiatric populations. This study investigated sNfL and GFAP levels in 412 adolescents diagnosed with anorexia…