14 hasil untuk "Li-Ling Lin"
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Artikel Jurnal
Revealing the molecular mechanism of gastric cancer marker annexin A4 in cancer cell proliferation using exon arrays.
Gastric cancer is a malignant disease that arises from the gastric epithelium. A potential biomarker for gastric cancer is the protein annexin A4 (ANXA4), an intracellular Ca(2+) sensor. ANXA4 is primarily found in epithelial cells, and is known to be involved in various biological processes…
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Artikel Jurnal
Placental mesenchymal dysplasia complicated with sudden fetal demise and amniotic fluid embolism: a case report
Abstract Background Placenta mesenchymal dysplasia (PMD) is a rare placental anomaly associated with various fetal and maternal complications. Whether close ultrasound surveillance can prevent intrauterine fetal demise (IUFD) in patients with PMD is still under investigation. Amniotic fluid…
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Artikel Jurnal
Unraveling fetal venous disorders: An integrated approach in fetal echocardiography and their clinical significance
Objective: Fetal venous system malformations frequently coincide with cardiac or extracardiac anomalies. This study explores our experience with an integrated fetal echocardiography approach and analyzes the characteristics and outcomes of fetal venous system disorders. Materials and methods: We…
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Artikel Jurnal Teks lengkap
2-Deoxy-d-Glucose Can Complement Doxorubicin and Sorafenib to Suppress the Growth of Papillary Thyroid Carcinoma Cells.
Tumor cells display a shift in energy metabolism from oxidative phosphorylation to aerobic glycolysis. A subset of papillary thyroid carcinoma (PTC) is refractory to surgery and radioactive iodine ablation. Doxorubicin and sorafenib are the drugs of choice for treating advanced thyroid cancer but…
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Artikel Jurnal
Assessment of adverse pregnancy outcomes associated with Helicobacter pylori infection
Abstract The background of Helicobacter pylori (H. pylori) infection is complex, and its influence on adverse pregnancy outcomes is inconsistently reported. We performed a multi-institutional, retrospective analysis using de-identified electronic health records from the TriNetX Research Network to…
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Artikel Jurnal
Contamination of ART culture Media–The role of semen and strategies for prevention
Objective: Microbial contamination of ART culture media is rare but serious. We examined our own experience and conducted a review of the literature with a view to preventing its occurrence and recurrence. Case report: A total of 12 cases were recorded during January 2006 to March 2019. The…
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Artikel Jurnal
Operando X‐Ray Absorption Spectroscopy Reveals Dynamic Interfacial Metal–Metal Coordination Governing CO2 Reduction Selectivity in PdAg Alloys
ABSTRACT Achieving high selectivity towards single carbon products in electrochemical CO2 reduction requires precise control over intermediate binding energies, a challenge that monometallic catalysts cannot address due to inherent electronic structure limitations. Bimetallic catalyst offers a…
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Artikel Jurnal
Structural basis of polyethylene glycol recognition by antibody
Abstract Background Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs and other applications. However, the underlying mechanism for specific PEG binding has not been elucidated. Methods The Fab of two…
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Artikel Jurnal
Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress neuroblastoma growth in mice
Neuroblastoma is characterized by a wide range of clinical manifestations and associated with poor prognosis when there is amplification of MYCN oncogene or high expression of Myc oncoproteins. In a previous in vitro study, we found that the glycolytic inhibitor 2-deoxyglucose (2DG) could suppress…
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Artikel Jurnal
Mendelian randomization analyses support causal relationship between brain imaging-derived phenotypes and risk of low back pain
Low back pain (LBP) has long been the leading cause of worldwide productivity loss and the top cause of years lived with disability. Observational studies have reported associations between brain imaging-derived phenotypes (IDPs) and LBP; however, it is uncertain whether these relationships are…
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Artikel Jurnal
Application of whole genome sequencing for carrier and diagnostic assessment of spinal muscular atrophy in Taiwan
Abstract This study aimed to evaluate the feasibility of whole-genome sequencing (WGS) combined with computational tools for spinal muscular atrophy (SMA) carrier screening and disease diagnosis in Taiwan. WGS data from 1492 Taiwan Biobank participants and two patients with SMA were analysed to…
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Artikel Jurnal
AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages
Summary: Tumor-associated macrophages (TAMs) are integral to the development of complex tumor microenvironments (TMEs) and can execute disparate cellular programs in response to extracellular cues. However, upstream signaling processes underpinning this phenotypic plasticity remain to be…
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Artikel Jurnal
Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination
Abstract While macrophage phagocytosis is an immune defense mechanism against invading cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel this engulfment. Here we report that the reverse signaling using CD47 as a receptor additionally enhances a pro-survival…