26 hasil untuk "Li-Min Yang"
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Solving Operating Room Scheduling Problem Using Artificial Bee Colony Algorithm
Many healthcare institutions are interested in reducing costs and in maintaining a good quality of care. The operating room department is typically one of the most costly units in a hospital. Hospital managers are always interested in finding effective ways of using operating rooms to minimize…
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Chimeras Reveal a Single Lipid-Interface Residue that Controls MscL Channel Kinetics as well as Mechanosensitivity
MscL, the highly conserved bacterial mechanosensitive channel of large conductance, serves as an osmotic “emergency release valve,” is among the best-studied mechanosensors, and is a paradigm of how a channel senses and responds to membrane tension. Although all homologs tested thus far encode…
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(1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride
The title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations…
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The complete chloroplast genome of Dryas octopetala var. asiatica (Dryadoideae, Rosaceae) and phylogenetic analysis
Dryas octopetala L. var. asiatica (Nakai) Nakai 1918 is a dwarf shrub that mainly grow in alpine and arctic zones of the Northern Hemisphere, representing an endemic variety in Asia. In the present study, the complete chloroplast (cp) genome of D. octopetala var. asiatica was first characterized…
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Activation of M1 mAChRs by lesatropane rescues glutamate neurotoxicity in PC12 cells via PKC-mediated phosphorylation of ERK1/2
Lesatropane, a synthesized chiral tropane (3S, 6S-isomer of satropane), is a novel muscarinic agonist, and is being under preclinical development in China for the treatment of primary glaucoma. The reports concerning that activation of muscarinic acetylcholine receptors (mAChRs) could protect cells…
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(1R,3S,5R,6S)-6-Acetoxy-3-(4-methylphenylsulfonyloxy)tropane
In the title compound [systematic name: (1R,3S,5R,6S)-8-methyl-3-(4-methylphenylsulfonyloxy)-8-azabicyclo[3.2.1]octan-6-yl acetate], C17H23NO5S, the fused piperidine ring exists in a chair conformation with the N atom and one C atom displaced by 0.876 (2) and −0.460 (3) Å, respectively, on opposite…
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Correction: Construction and Analysis of High-Complexity Ribosome Display Random Peptide Libraries
Juga tersedia di: DOAJ
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Artikel Jurnal Teks lengkap
Construction and Analysis of High-Complexity Ribosome Display Random Peptide Libraries
Random peptide libraries displayed on the ribosome are becoming a new tool for the in vitro selection of biologically relevant macromolecules, including epitopes, antagonists, enzymes, and cell-surface receptors. Ribosome display is a cell-free system of coupling individual nascent proteins…
Juga tersedia di: DOAJ
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(1R,3S,5R,6S)-6-Acetoxy-8-methyl-3-(p-tolylsulfonyloxy)-8-azoniabicyclo[3.2.1]octane (2R,3R)-2,3-bis(benzoyloxy)-3-carboxypropanoate
The title compound, C17H24NO5S+·C18H13O8−, is the key intermediate during the preparation of lesatropane [systematic name (1R,3S,5R,6S)-6-acetoxy-3-(4-methylphenylsulfonyloxy)tropane], a potential antiglaucoma agent. The tertiary N atom of the tropane ring is involved in intermolecular…
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Mechanical Properties and Service Life Prediction of Modified Concrete Attacked by Sulfate Corrosion
Under the condition of drying and wetting circulation, ordinary concrete, modified concrete containing fly ash, and double-admixture concrete containing fly ash and polypropylene fiber were corroded in the solution of Na2SO4 and (NH4)2SO4. The sulfate concentration of the solution was designed to…
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(Butane-1,2,3,4-tetraol-κ3O1,O2,O3)(ethanol-κO)tris(nitrato-κ2O,O′)holmium(III)
In the title HoIII–erythritol complex, [Ho(NO3)3(C4H10O4)(C2H5OH)], the HoIII cation is chelated by a tridentate erythritol ligand and three bidentate nitrate anions. An ethanol molecule further coordinates the HoIII cation, completing the irregular O10 coordination geometry. In the crystal, an…
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[(2R,3S)-Butane-1,2,3,4-tetraol-κ3O1,O2,O3](ethanol-κO)tris(nitrato-κ2O,O′)samarium(III)
The title SmIII–erythritol complex, [Sm(NO3)3(C2H6O)(C4H10O4)], is isotypic with its Nd, Eu, Y, Gd, Tb and Ho analogues. The SmIII cation exhibits a coordination number of ten and is chelated by a tridentate erythritol ligand and three bidentate nitrate anions. It is additionally coordinated by an…
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Protective Effects of Fermented Lycium barbarum Polysaccharides on the Intestine in D-Galactose-Induced Aging Mouse Model
Objective: To investigate the protective effect of fermented Lycium barbarum polysaccharides (FLBP) on the intestine in an aging mouse model. Methods: The aging model was established by continuous subcutaneous injection of 1 000 mg/(kg mb · d) D-galactose in the back of the neck, followed by gavage…
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SLAF marker based QTL mapping of fruit-related traits reveals a major-effect candidate locus ff2.1 for flesh firmness in melon
Flesh firmness (FF) is an important and complex trait for melon breeders and consumers. However, the genetic mechanism underlying FF is unclear. Here, a soft fruit melon (P5) and a hard fruit melon (P10) were crossed to generate F2, and the FF and fruit-related traits were recorded for two years…
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Complete mitochondrial genome of the radicine pond snail Radix plicatula (Gastropoda: Lymnaeidae)
Radix plicatula is broadly distributed in China, as well as Russia. It is one of the intermediate hosts of Fasciola species which leads to the spread of fascioliasis. Here, we first described the complete mitochondrial genome of R. plicatula. The mitogenome is 13,751 bp in length, containing 13…
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Chromosome-level genome assembly of Oncomelania hupensis: the intermediate snail host of Schistosoma japonicum
Abstract Background Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis, which is a significant cause of morbidity in China, the Philippines and Indonesia. Oncomelania hupensis (Gastropoda: Pomatiopsidae) is the unique intermediate host of S. japonicum. A complete genome…
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Long-distance spread of Tembusu virus, and its dispersal in local mosquitoes and domestic poultry in Chongming Island, China
Abstract Background Chongming Island in China serves as a breeding and shelter point on the East Asian–Australasian Flyway. The resting frequency of migratory birds, abundance of mosquito populations, and the popular domestic poultry industry pose a potential risk of mosquito-borne zoonotic…
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Population genetic diversity of invasive Pomacea snails and surveillance of Angiostrongylus cantonensis in Shanghai, East China
Abstract Background Golden apple snails (Gastropoda: Ampullariidae: Pomacea) were introduced into China in the 1980s for aquaculture and have since become widespread agricultural pests across East Asia. In addition to their invasive impact, they are a key intermediate host of the rat lungworm…