109 results for "Parth Patel"
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Journal Article
A bird's eye view on a therapeutically ‘wonder molecule’: Berberine
Berberine is a quaternary ammonium salt and naturally occurring benzylisoquinoline alkaloid, present in numerous medicinal herbs’ roots and stem bark as an active constituent, especially in the genus Berberis. It contains many pharmacological properties such as antioxidant, antiviral, antidiabetic…
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Journal Article
Recurrence of Prostate Cancer with Cutaneous Metastasis after Radical Prostatectomy
While cutaneous metastases are already extremely rare in primary metastatic prostatic adenocarcinoma, cutaneous manifestations in recurrent prostate cancer have rarely been described prior to this report. Here we present the case report of a 93-year-old male who underwent radical prostatectomy but…
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Journal Article
Ojodushti and Systemic Amyloidosis: An Ayurveda perspective on Protein Misfolding Disorders
Background: In Ayurveda, Ojas (vital essence) is described as the final essence formed after proper nourishment of the seven body tissues known as Saptadhatus. Ojas is responsible for maintaining strength, immunity (Vyadhikshamatva), and overall balance in the body. When the quality of Ojas becomes…
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Histological and Morphometric Analysis with Grading of Atherosclerosis-Associated Myocardial Changes in Cases of Sudden Death at a Tertiary Care Hospital
Background: Sudden cardiac death (SCD) remains a significant public health concern worldwide, representing a considerable proportion of mortality linked to cardiovascular diseases. Atherosclerosis, a progressive disease characterized by the accumulation of lipids, fibrous elements, and inflammatory…
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The need for improved dermoscopy training in residency: a survey of US dermatology residents and program directors
Background: Inadequate dermoscopy training represents a major barrier to proper dermoscopy use. Objective: To better understand the status of dermoscopy training in US residency programs. Methods: A survey was sent to 417 dermatology residents and 118 program directors of dermatology residency…
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Journal Article
Acute fulminant myocarditis as a rare manifestation in complicated scrub typhus: A case report
Scrub typhus or Tsutsugamushi disease is a febrile illness caused by bacteria of the family Rickettsiaceae and named Orientia Tsutsugamushi. Severe complications such as acute respiratory distress syndrome (ARDS), encephalitis, interstitial pneumonia, acute renal failure, acute hepatic failure and…
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Journal Article
Marfan Syndrome with Quadricuspid Aortic Valve
Marfan syndrome is commonly associated with cardiovascular abnormalities such as aortic root dilatation, aneurysm, dissection, mitral valve prolapse, and pulmonary artery dilatation. However, its association with a quadricuspid aortic valve (QAV) is exceedingly rare. To the best of our knowledge…
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Journal Article
Radiotherapy for inoperable Merkel cell carcinoma: a systematic review and pooled analysis
Background: Cumulative data on radiation monotherapy for Merkel cell carcinoma (MCC) is lacking. Objective: We sought to synthesize all available data on treatment outcomes for radiation monotherapy for inoperable stage I-III MCC. Methods: We performed a systematic review of the current literature…
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Evaluation of bacterial contamination of dental unit water lines before and after the use of 1% (Lysoformin 3000) disinfectant and awareness of the dental unit waterline disinfection among the practicing dental surgeons of Vadodara city
Purpose: The aim is to evaluate the bacterial contamination in dental unit waterlines (DUWLs) before and after the use of the disinfectant 1% (Lysoformin 3000) for its efficacy also assess the awareness about the same among the practicing dental surgeons of Vadodara city. Methodology: A volume of…
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Journal Article
Association between Digestive and Metabolic status with Haematological parameters in healthy individuals: A cross-sectional study
Background: In Ayurveda, Agni represents the biological force responsible for digestion, metabolism, and tissue nourishment. Among the thirteen types of Agni (digestive fire), Jatharagni (primary digestive fire located in the gastrointestinal tract) is regarded as the primary type that regulates…
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Journal Article
Metabolic-Associated Steatotic Liver Disease: From Molecular Mechanisms to Novel Therapies
Metabolic-associated steatotic liver disease (MASLD) is a burgeoning worldwide burden and is currently the leading indication for a liver transplant. Despite the growing burden of disease, there are few pharmacological treatments available. The underlying molecular mechanisms of the development of…
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Penile Gangrene with Abscess Formation after Modified Al-Ghorab Shunt for Idiopathic Ischemic Priapism
Penile gangrene is a rare but unfortunate complication of surgical intervention and priapism shunts. The literature regarding penile gangrene following surgical correction of priapism is sparse, the majority of which dates back to thirty to forty years. Here, we present the case of a 60-year-old…
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Journal Article Full text
Desformylflustrabromine (dFBr), a positive allosteric modulator of α 4 β 2 nicotinic acetylcholine receptors decreases voluntary ethanol consumption and preference in male and female Sprague-Dawley rats
Alcohol use disorder is a medical condition that impacts millions of individuals worldwide. Although there are a few pharmacotherapeutic options for alcohol-dependent individuals; there is a need for the development of novel and more effective therapeutic approaches. Alcohol and nicotine are…
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Journal Article Full text
Chitosan Nanoparticles at the Biological Interface: Implications for Drug Delivery
The unique properties of chitosan make it a useful choice for various nanoparticulate drug delivery applications. Although chitosan is biocompatible and enables cellular uptake, its interactions at cellular and systemic levels need to be studied in more depth. This review focuses on the various…
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Formulation, Organoleptic Evaluation, and Acceptability of Various Teas from Underutilized Nutritious Herbs Compared with Marketed Chinese and Yellow Lipton Tea
Herbal teas are nutrient, antioxidant, and hydration rich brews made from herbs and spices and taken for various purposes. The objective of this study was to formulate tea from clove (Syzygium aromaticum), leaves of lemongrass (Cymbopogon citratus), guava (Psidium guajava), and moringa (Moringa…
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The use of three-dimensional-printed guides, static navigation, and bioactive materials to treat bilateral and double dens invaginatus
Dens invaginatus (DI) represents abnormality in tooth morphology showing inward folding of enamel and dentin toward the pulp cavity from the coronal part. When the infolding extends to as far as the root apex, it is classified as DI Oehlers Type III. Double invagination is all the more a rare…
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Journal Article
Obésité et vieillissement en santé : bien-être social, fonctionnel et mental chez les personnes âgées au Canada
Introduction. Si les Canadiens vivent plus longtemps qu’avant, bon nombre d’entre eux souffrent cependant d’obésité. Cette étude vise à décrire, par un examen de mesures du bien-être social, fonctionnel et mental, le vieillissement des personnes âgées souffrant d’obésité ayant participé à l’Étude…
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A study on perception of medical students regarding implementation of elective module in India
As suggested by the National Medical Commission (NMC) of India recently, the elective module was implemented in our medical college for MBBS admission batch 2019. Since, this was the first of its kind implementation in our institute and across the country, we planned this study to know the…
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Journal Article Full text
Effective Heart Disease Prediction Using Machine Learning Techniques
The diagnosis and prognosis of cardiovascular disease are crucial medical tasks to ensure correct classification, which helps cardiologists provide proper treatment to the patient. Machine learning applications in the medical niche have increased as they can recognize patterns from data. Using…
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Journal Article
Obesity and healthy aging: social, functional and mental well-being among older Canadians
Introduction: Canadians are living longer than before, and a large proportion of them are living with obesity. The present study sought to describe how older participants in the Canadian Longitudinal Study on Aging (CLSA) who are living with obesity are aging, through an examination of measures of…