13 hasil untuk "Pascal Chavanet"
Menampilkan 1–13 · 1,02 detik · RSS
-
Artikel Jurnal
Addition of daptomycin for the treatment of pneumococcal meningitis: protocol for the AddaMAP study
Background The leading cause of acute bacterial meningitis in adults is Streptococcus pneumoniae. This infection is associated with high rates of mortality and morbidity related, among other factors, to the excessive host response to the pneumococcal lysis. Experimental in vitro and in vivo data…
-
Artikel Jurnal Teks lengkap
Detection of Temporal Clusters of Healthcare-Associated Infections or Colonizations with Pseudomonas aeruginosa in Two Hospitals: Comparison of SaTScan and WHONET Software Packages
The identification of temporal clusters of healthcare-associated colonizations or infections is a challenge in infection control. WHONET software is available to achieve these objectives using laboratory databases of hospitals but it has never been compared with SaTScan regarding its detection…
Juga tersedia di: DOAJ
-
Artikel Jurnal
Increased VLDL-apoB and IDL-apoB production rates in nonlipodystrophic HIV-infected patients on a protease inhibitor-containing regimen
The aim of this study was to identify the first abnormalities of apolipoprotein B (apoB) metabolism in HIV-infected patients treated by antiretroviral therapy (ART) with protease inhibitors (PIs). The influence of ART on the metabolism of apoB in VLDL, IDL, and LDL was investigated in six patients…
-
Artikel Jurnal Teks lengkap
Kineret ® /IL-1ra Blocks the IL-1/IL-8 Inflammatory Cascade during Recombinant Panton Valentine Leukocidin-Triggered Pneumonia but Not during S. aureus Infection
Objectives: Community-acquired Staphylococcus aureus necrotizing pneumonia is a life-threatening disease. Panton Valentine Leukocidin (PVL) has been associated with necrotizing pneumonia. PVL triggers inflammasome activation in human macrophages leading to IL-1β release. IL-1β activates lung…
Juga tersedia di: DOAJ
-
Artikel Jurnal
In vitro antimicrobial activity of daptomycin alone and in adjunction with either amoxicillin, cefotaxime or rifampicin against the main pathogens responsible for bacterial meningitis in adults
ABSTRACT: Objectives: As daptomycin adjunction is currently under clinical evaluation in the multicentre phase II AddaMAP study to improve the prognosis of pneumococcal meningitis, the present work aimed at evaluating the in vitro antimicrobial activity of daptomycin-based combinations against some…
-
Artikel Jurnal
Acute kidney injury during invasive listeriosis: frequence, risk factors, and prognostic impact in a multicenter cohort (REALIST study)
Objective: Invasive listeriosis carries high mortality, and acute kidney injury (AKI) may complicate hospitalization and worsen outcomes. However, its incidence, risk factors, and prognostic impact in this setting remain poorly described. We aimed to evaluate AKI in patients hospitalized for…
-
Artikel Jurnal
Dalbavancin treatment for prosthetic joint infections in real-life: a national cohort study and literature review
ABSTRACT: Objectives: Dalbavancin is a long-lasting lipoglycopeptide active against Gram-positive bacteria, especially methicillin-resistant staphylococci. Few data are available on dalbavancin use for treatment of prosthetic joint infections (PJIs). We describe a cohort of patients treated for PJI…
-
Artikel Jurnal
Correction to: The dysregulated innate immune response in severe COVID-19 pneumonia that could drive poorer outcome
An amendment to this paper has been published and can be accessed via the original article.
-
Artikel Jurnal
The dysregulated innate immune response in severe COVID-19 pneumonia that could drive poorer outcome
Abstract Background Although immune modulation is a promising therapeutic avenue in coronavirus disease 2019 (COVID-19), the most relevant targets remain to be found. COVID-19 has peculiar characteristics and outcomes, suggesting a unique immunopathogenesis. Methods Thirty-six immunocompetent…