40 hasil untuk "Ping-Chang Lin"

Low frequency of asymptomatic dengue virus-infected donors in blood donor centers during the largest dengue outbreak in Taiwan

Jih-Jin Tsai; Ping-Chang Lin; Ching-Yi Tsai dkk.

PLOS ONE, Vol. 13 No. 10 · 2018 · Inggris · PLOS Scopus

To determine the prevalence of asymptomatic dengue virus-infected blood donors during the largest dengue outbreak in Taiwan history occurred in 2015, we examined the evidence of dengue virus (DENV) infection by the detection of DENV RNA genome using real-time reverse transcription-polymerase chain…

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Comparative Evaluation of Five Multimodal Large Language Models for Medical Laboratory Image Recognition: Impact of Prompting Strategies on Diagnostic Accuracy

Hui-Ru Yang; Kuei-Ying Lin; Ping-Chang Lin dkk.

Diagnostics, Vol. 16 No. 9 · 2026 · Inggris · DOAJ Scopus

Background: Multimodal large language models (MLLMs) show promise in medical imaging, but their performance is highly dependent on prompt engineering. This study systematically evaluates how different prompting strategies affect diagnostic accuracy in clinical laboratory image interpretation…

Disseminated melioidosis complicated by symmetrical peripheral gangrene and multi-organ failure: a case report

Chen-Hsuan Lin; Ping-Chang Lin; Ching-Yi Tsai dkk.

Frontiers in Immunology, Vol. 17 · 2026 · Inggris · DOAJ Scopus

BackgroundMelioidosis, caused by Burkholderia pseudomallei, is a potentially fatal infection endemic to Southeast Asia and northern Australia. Disseminated disease with bacteremia and multifocal organ involvement carries high mortality, particularly among patients with diabetes mellitus (DM) and…

Multiparametric Classification of Skin from Osteogenesis Imperfecta Patients and Controls by Quantitative Magnetic Resonance Microimaging

Beth G. Ashinsky; Kenneth W. Fishbein; Erin M. Carter dkk.

PLOS ONE, Vol. 11 No. 7 · 2016 · Inggris · PLOS Scopus

The purpose of this study is to evaluate the ability of quantitative magnetic resonance imaging (MRI) to discriminate between skin biopsies from individuals with osteogenesis imperfecta (OI) and skin biopsies from individuals without OI. Skin biopsies from nine controls (unaffected) and nine OI…

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Comparison of two rapid diagnostic tests during a large dengue virus serotype 3 outbreak in the Solomon Islands in 2013

Li-Teh Liu; Tenneth Dalipanda; Rooney Jagilly dkk.

PLOS ONE, Vol. 13 No. 8 · 2018 · Inggris · PLOS Scopus

Dengue virus (DENV) infection causes various clinical presentations, including asymptomatic infection, dengue with or without warning signs and severe dengue. An early and accurate diagnosis of DENV infection during the first few days of illness supports clinical management and significantly…

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Seroprevalence of dengue virus in two districts of Kaohsiung City after the largest dengue outbreak in Taiwan since World War II

Jih-Jin Tsai; Ching-Kuan Liu; Wen-Yang Tsai dkk.

PLOS Neglected Tropical Diseases, Vol. 12 No. 10 · 2018 · Inggris · PLOS Scopus

Dengue virus (DENV) is the leading cause of arboviral diseases in humans worldwide. In this study, we investigated the seroprevalence of DENV infection in two districts of Kaohsiung City, a metropolis in southern Taiwan, where major dengue outbreaks have occurred in the past three decades. We…

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The epidemiology and identification of risk factors associated with severe dengue during the 2023 dengue outbreak in Kaohsiung City, Taiwan

Li-Teh Liu; Shi-Ya Huang; Chen-Hsuan Lin dkk.

Travel Medicine and Infectious Disease, Vol. 65 · 2025 · Inggris · DOAJ Scopus

After the previous major dengue fever (DF) outbreaks in 2014 and 2015 in Taiwan, the second-largest DF outbreak re-emerged in 2023. A total of 178 patients with laboratory-confirmed dengue virus (DENV) infection, including 92 DENV-1 and 86 DENV-2 cases, were enrolled in this study conducted during…

Defining the clinical utility of dengue RT-iiPCR: stratification by days post-onset and primary vs. secondary infection during the 2023 Taiwan outbreak

Li-Teh Liu; Po-Chih Chen; Ping-Chang Lin dkk.

Travel Medicine and Infectious Disease, Vol. 69 · 2026 · Inggris · DOAJ Scopus

Background: Rapid molecular diagnostics are critical for timely dengue virus (DENV) detection, especially in resource-limited settings. Reverse transcription-insulated isothermal polymerase chain reaction (RT-iiPCR) enables sample-to-answer amplification without thermocyclers. While this platform…

Evaluation of rapid diagnostic tests to detect dengue virus infections in Taiwan

Li-Teh Liu; Chun-Hong Chen; Ching-Yi Tsai dkk.

PLOS ONE, Vol. 15 No. 9 · 2020 · Inggris · PLOS Scopus

Early diagnosis is important for the clinical management of diseases caused by dengue virus (DENV) infections. We investigated the performance of three commercially available DENV nonstructural protein 1 (NS1) rapid diagnostic tests (RDTs) using 173 acute-phase sera collected from dengue…

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Evaluation of a new NS1 rapid diagnostic test using a single acute‐phase serum panel collected during the largest dengue outbreak in Taiwan history in 2015

Li‐Teh Liu; Chun‐Hong Chen; Ping‐Chang Lin dkk.

Kaohsiung Journal of Medical Sciences, Vol. 38 No. 4 · 2022 · Inggris · DOAJ Scopus

Abstract Dengue virus (DENV) infection results mostly from the bites of virus‐carrying Aedes mosquitoes, which results in dengue fever (DF) with or without warning signs, severe dengue, or asymptomatic infections in humans. For point‐of care identification of DENV‐infected patients, a rapid…

CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma

Kartik Angara; Thaiz F. Borin; Mohammad H. Rashid dkk.

Neoplasia: An International Journal for Oncology Research, Vol. 20 No. 10 · 2018 · Inggris · DOAJ Scopus

BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified highly upregulated interleukin 8 (IL-8)-CXCR2 axis…

Performance comparison of two dengue NS1 rapid diagnostic tests against RT-PCR: Sensitivity and specificity across infections and timeframes

Li-Teh Liu; Po-Chih Chen; Chen-Hsuan Lin dkk.

Journal of Infection and Public Health, Vol. 18 No. 11 · 2025 · Inggris · DOAJ Scopus

Background: Dengue virus (DENV) is a mosquito-borne flavivirus that remains a global public health threat, particularly in tropical regions where it is endemic. Accurate and timely diagnosis is critical for optimal patient care and effective outbreak containment. While reverse…

Diagnostic performance of a field-deployable iiPCR platform and viral load dynamics of MPXV Clade IIb in a cohort with high prevalence of HIV

Li-Teh Liu; Chao-Ju Chen; Ping-Chang Lin dkk.

Annals of Medicine, Vol. 58 No. 1 · 2026 · Inggris · DOAJ Scopus

Background Since 2022, the global outbreak of Mpox caused by the Mpox virus (MPXV) Clade IIb has underscored the need for timely and decentralized molecular diagnostics. Although quantitative real-time PCR (qPCR) remains the diagnostic gold standard, its infrastructure requirements may limit…

Comparing the performance of dengue virus IgG and IgG-capture enzyme-linked immunosorbent assays in seroprevalence study

Jih-Jin Tsai; Ching-Yi Tsai; Ping-Chang Lin dkk.

BMC Infectious Diseases, Vol. 23 No. 1 · 2023 · Inggris · DOAJ Scopus

Abstract Background Dengue virus (DENV) is the leading cause of arboviral diseases in humans worldwide. Currently Dengvaxia, the first dengue vaccine licensed in 20 countries, was recommended for DENV seropositive individuals aged 9–45 years. Studying dengue seroprevalence can improve our…