17 hasil untuk "Sam Pepper"
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Artikel Jurnal
Building an evaluation infrastructure to capture process and progress within a Clinical and Translational Science Awards hub
To improve its management capacity, Frontiers Clinical and Translational Science Institute overhauled its evaluation infrastructure to be comprehensive, efficient, and transparent in demonstrating outputs and outcomes. We built a platform that standardized measures across program areas, integrated…
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180 Building an evaluation platform to capture the impact of Frontiers CTSI activities
OBJECTIVES/GOALS: In 2021, Frontiers CTSI revamped its evaluation infrastructure to be comprehensive, efficient, and transparent in demonstrating outputs and outcomes. We sought to build a platform to standardize measures across program areas, integrate continuous improvement processes into…
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Rurality Impacts Mammography Screening Adherence Among Mid-life Women in the Kansas Region
Objective The gold standard for breast cancer screening and prevention is regular mammography; thus, understanding what impacts adherence to this standard is essential in limiting cancer-associated costs. We assessed the impact of various understudied sociodemographic factors of interest on…
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The Effects of COVID-19 Pandemic Policy on Social Needs Across the State of Kansas and Western Missouri: Paired Survey Response Testing
BackgroundStudying patients’ social needs is critical to the understanding of health conditions and disparities, and to inform strategies for improving health outcomes. Studies have shown that people of color, low-income families, and those with lower educational attainment experience greater…
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Evaluating the risk of comorbidity onset in elderly patients after a cancer diagnosis
Abstract Background Cancer is a critical disease that affects a person physically, mentally, socially, and in many other aspects. During the treatment stage of cancer, patients suffer from various health complexities, especially elderly people, which might result in the onset of other diseases…
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A regional study to evaluate the impact of coal-fired power plants on lung cancer incident rates
Background: Lung cancer is the leading cause of cancer related deaths. In Kansas, where coal-fired power plants account for 34% of power, we investigated whether hosting counties had higher age-adjusted lung cancer incidence rates. We also examined demographics, poverty levels, percentage of…
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A community informed geospatial assessment of breast cancer screening and outreach priorities in Kansas
Purpose: Project BRA (Breast Cancer Risk Assessment), conducted in partnership with the Breast Cancer Health Equity Task Force, used a community–informed geospatial approach to evaluate inequities in breast cancer (BC) screening and incidence across the University of Kansas Cancer Center (KUCC)…
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Predicting dementia risk using neuroimaging and cognitive assessment
Introduction: Dementia affects over 55 million people globally, with numbers expected to double in the coming decades. Early detection is critical, yet traditional risk assessments relying on age, family history, and basic cognitive tests often fall short. This study explores whether combining…
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Financial toxicity and multidimensional economic strain among dementia caregivers
Abstract INTRODUCTION Financial toxicity is an underrecognized but significant burden among caregivers of individuals with Alzheimer's disease and related dementias (ADRD). The interactions among economic hardship, caregiver burden, and social determinants of health (SDOH) remain poorly defined…
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Bolstering the complex study start-up process at NCI cancer centers using technology
Background: The study startup process for interventional clinical trials is a complex process that involves the efforts of many different teams. Each team is responsible for their startup checklist in which they verify that the necessary tasks are done before a study can move on to the next team…
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Estimating the uninsured cancer rate: Unraveling the indelible link between insurance, age, and the accessibility of cancer treatment
Introduction: Patients without insurance often wait until their symptoms become severe before seeking treatment. While done to avoid the cost of preventative care, this decision leads to uninsured patients presenting with more advanced diseases.Hypothesis: We aim to calculate the overall uninsured…
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Spatial analysis of lung cancer mortality and its potential risk factors: a regional study in Kansas
Introduction: Lung cancer is a leading cause of cancer deaths in the U.S., with significant geographic disparities in incidence and mortality. Understanding the relationship between spatial variations and other risk factors to lung cancer mortality counts (LCMC) is critical for guiding targeted…
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Analyzing diversity trends in dermatology: A comprehensive overview
Background: Dermatology lags behind other medical specialties in workforce diversity, particularly regarding gender, race, and ethnicity. This study aims to analyze the current demographics of dermatology physicians in the United States, comparing them with other medical specialties, the overall…
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A Hybrid Technology-Enabled Financial Navigation Model to Combat Financial Toxicity in Cancer Care
Financial toxicity is increasingly recognized as a critical barrier to high-quality cancer care, treatment adherence, and positive survivorship outcomes. Despite the availability of financial and social support resources, patients often face challenges in accessing and navigating them effectively…
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A Geographic Disparities Analysis Between Standard of Care and Clinical Trial CAR‐T Patients in Kansas
ABSTRACT Background This study compares demographics and geographic factors associated with access to chimeric antigen receptor (CAR)‐T cell therapy for B‐cell malignancies or multiple myeloma: individuals in clinical trials at the University of Kansas Cancer Center (KUCC) and those receiving…
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Near–Real-Time Clinical Trial Accrual Dashboard in a National Cancer Institute–Designated Cancer Center: Mixed Methods Implementation Study
BackgroundClinical trial accrual monitoring is a critical component of trial operations, influencing feasibility, timeliness, and scientific validity. Despite its importance, many National Cancer Institute–designated cancer centers continue to rely on static spreadsheets or manually generated…
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Limbic-predominant neuroimaging correlates of plasma p-Tau217 in preclinical and clinical Alzheimer’s disease
BackgroundPlasma phosphorylated tau at threonine 217 (p-Tau217) has emerged as a highly sensitive and specific blood-based biomarker for Alzheimer’s Disease (AD). However, its regional brain correlates with multimodal neuroimaging, beyond tau-PET, remain underexplored, particularly in early disease…