12 hasil untuk "Tianshuang Liu"
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Artikel Jurnal Teks lengkap
Prediction of Jacking Force for Construction of Long-Distance Rectangular Utility Tunnel Using Differential Evolution–Bidirectional Gated Re-Current Unit–Attention Model
Most of the current machine learning algorithms are applied to predict the jacking force required in micro-tunneling; in contrast, few studies about long-distance, large-section jacking projects have been reported in the literature. In this study, an intelligent framework, consisting of a…
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Artikel Jurnal Teks lengkap
Human Metapneumovirus Glycoprotein G Disrupts Mitochondrial Signaling in Airway Epithelial Cells
Human metapneumovirus (hMPV) is a recently identified RNA virus belonging to the Paramyxoviridae family. It is a common cause of respiratory tract infections in children, adults, and immunocompromised patients, for which no specific treatment or vaccine is available. Recent investigations in our…
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Artikel Jurnal Teks lengkap
Human Metapneumovirus Glycoprotein G Inhibits Innate Immune Responses
Human metapneumovirus (hMPV) is a leading cause of acute respiratory tract infection in infants, as well as in the elderly and immunocompromised patients. No effective treatment or vaccine for hMPV is currently available. A recombinant hMPV lacking the G protein (rhMPV-ΔG) was recently developed as…
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Artikel Jurnal
GFDet: Multi-Level Feature Fusion Network for Caries Detection Using Dental Endoscope Images
Early dental caries detection by endoscope can prevent complications, such as pulpitis and apical infection. However, automatically identifying dental caries remains challenging due to the uncertainty in size, contrast, low saliency, and high interclass similarity of dental caries. To address these…
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Artikel Jurnal Teks lengkap
Hydrogen Sulfide Donor GYY4137 Rescues NRF2 Activation in Respiratory Syncytial Virus Infection
Respiratory syncytial virus (RSV) can cause severe respiratory illness in infants, immunocompromised, and older adults. Despite its burden, no vaccine or specific treatment is available. RSV infection is associated with increased reactive oxygen species (ROS) production, degradation of the…
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Artikel Jurnal Teks lengkap
Human Metapneumovirus Inhibits IFN-β Signaling by Downregulating Jak1 and Tyk2 Cellular Levels
Human metapneumovirus (hMPV), a leading cause of respiratory tract infections in infants, inhibits type I interferon (IFN) signaling by an unidentified mechanism. In this study, we showed that infection of airway epithelial cells with hMPV decreased cellular level of Janus tyrosine kinase (Jak1)…
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Artikel Jurnal Teks lengkap
Analysis of Proteins and Piwi-Interacting RNA Cargo of Extracellular Vesicles (EVs) Isolated from Human Nose Organoids and Nasopharyngeal Secretions of Children with RSV Infections
Respiratory syncytial virus (RSV) is the leading cause of respiratory infections in children. Extracellular vesicles (EVs), released by airway epithelial cells, contain proteins and different families of non-coding RNAs (EV cargo) that can modulate the responses of target cells to viral infection…
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Artikel Jurnal
Respiratory syncytial virus infection changes the piwi-interacting RNA content of airway epithelial cells
Piwi-interacting RNAs (piRNAs) are small non-coding RNAs (sncRNAs) of about 26–32 nucleotides in length and represent the largest class of sncRNA molecules expressed in animal cells. piRNAs have been shown to play a crucial role to safeguard the genome, maintaining genome complexity and integrity…
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Artikel Jurnal
PIWIL4 regulates gene expression and piRNA levels in RSV-infected airway epithelial cells
Summary: Respiratory syncytial virus (RSV) causes acute lower respiratory tract infection in young children, the elderly, and immunocompromised hosts, and no RSV vaccine or therapy exists for infants, beyond prophylaxis. PIWI-interacting RNAs (piRNAs), small non-coding RNAs acting through P…