44 hasil untuk "Tim Becker"
Menampilkan 1–20 · 0,56 detik · RSS
-
Artikel Jurnal
Simulation Software for the Virtual Design and Analysis of Magnetic Sensor Systems
Designing magnetic sensor modules is a complex process often relying on simulation to avoid costly and time-consuming prototypes. However, existing simulation tools are typically generic, leading to key limitations: magnetic field data cannot be exported for detailed analysis, interfaces are…
-
Artikel Jurnal Teks lengkap
Advanced In Vivo Prediction by Introducing Biphasic Dissolution Data into PBPK Models
Coupling biorelevant in vitro dissolution with in silico physiological-based pharmacokinetic (PBPK) tools represents a promising method to describe and predict the in vivo performance of drug candidates in formulation development including non-passive transport, prodrug activation, and first-pass…
-
Artikel Jurnal Teks lengkap
Charged Atmospheric Aerosols from Charged Saltating Dust Aggregates
Grain collisions in aeolian events, e.g., due to saltation, result in atmospheric aerosols. They may regularly be electrically charged, but individual charge balances in collisions including small grains are not easily obtained on the ground. We therefore approach this problem in terms of…
-
Artikel Jurnal
Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
Plain language summary The clinical course of patients with COVID-19 is highly variable, with some patients barely affected and others dying. We wanted to better understand why this is the case and identify markers of COVID-19-associated mortality. To this end, we looked into the entire available…
-
Artikel Jurnal Teks lengkap
A novel validation algorithm allows for automated cell tracking and the extraction of biologically meaningful parameters.
Automated microscopy is currently the only method to non-invasively and label-free observe complex multi-cellular processes, such as cell migration, cell cycle, and cell differentiation. Extracting biological information from a time-series of micrographs requires each cell to be recognized and…
Juga tersedia di: PLOS
-
Artikel Jurnal Teks lengkap
Use of digital teaching resources and predictors of medical student performance during the pandemic: A prospective study.
BackgroundThe coronavirus pandemic has led to increased use of digital teaching formats in medical education. A number of studies have assessed student satisfaction with these resources. However, there is a lack of studies investigating changes in student performance following the switch from…
-
Artikel Jurnal
A comparison of open or laparoscopic colectomy outcomes for the management of ischemic colitis using the ACS-NSQIP database
Introduction: Ischemic colitis is a common manifestation of intestinal ischemia and is potentially a surgical emergency. Although such surgical emergencies were historically approached via open exploration, it is uncertain if there is a role for minimally invasive techniques. This study compares…
-
Artikel Jurnal
Artificial Intelligence for Prognostic Scores in Oncology: a Benchmarking Study
Introduction: Prognostic scores are important tools in oncology to facilitate clinical decision-making based on patient characteristics. To date, classic survival analysis using Cox proportional hazards regression has been employed in the development of these prognostic scores. With the advance of…
-
Artikel Jurnal Teks lengkap
Risky behavior during stair descent for young adults: Differences in men versus women
Injuries commonly occur on stairs, with high injury rates in young adults, especially young women. High injury rates could result from physiological and/or behavioral differences; this study focuses on behaviors. The purposes of this observational study were (1) to quantify young adult behaviors…
Juga tersedia di: DOAJ
-
Artikel Jurnal
Discovery of novel eGFR-associated multiple independent signals using a quasi-adaptive method
A decreased estimated glomerular filtration rate (eGFR) leading to chronic kidney disease is a significant public health problem. Kidney function is a heritable trait, and recent application of genome-wide association studies (GWAS) successfully identified multiple eGFR-associated genetic loci. To…
-
Artikel Jurnal Teks lengkap
A One-Degree-of-Freedom Test for Supra-Multiplicativity of SNP Effects
Deviation from multiplicativity of genetic risk factors is biologically plausible and might explain why Genome-wide association studies (GWAS) so far could unravel only a portion of disease heritability. Still, evidence for SNP-SNP epistasis has rarely been reported, suggesting that 2-SNP models…
Juga tersedia di: DOAJ
-
Artikel Jurnal
Optical Constants of Martian Dust Analogs at UV–Visible–Near-infrared Wavelengths
We present an advanced light-scattering model to retrieve the optical constants of three Martian dust analogs: Johnson Space Center regolith simulant, Enhanced Mojave Mars Simulant, and Mars Global Simulant. The samples are prepared to have narrow particle-size distributions within the…
-
Artikel Jurnal
Genetic information from discordant sibling pairs points to ESRP2 as a candidate trans-acting regulator of the CF modifier gene SCNN1B
Abstract SCNN1B encodes the beta subunit of the epithelial sodium channel ENaC. Previously, we reported an association between SNP markers of SCNN1B gene and disease severity in cystic fibrosis-affected sibling pairs. We hypothesized that factors interacting with the SCNN1B genomic sequence are…
-
Artikel Jurnal
Predicting compound activity from phenotypic profiles and chemical structures
Experimental assays are used to determine if compounds cause a desired activity in cells. Here the authors demonstrate that computational methods can predict compound bioactivity given their chemical structure, imaging and gene expression data from historic screening libraries.
-
Artikel Jurnal
Single nucleotide polymorphisms in the angiogenic and lymphangiogenic pathways are associated with lymphedema caused by Wuchereria bancrofti
Abstract Background Lymphedema (LE) is a chronic clinical manifestation of filarial nematode infections characterized by lymphatic dysfunction and subsequent accumulation of protein-rich fluid in the interstitial space—lymphatic filariasis. A number of studies have identified single nucleotide…