76 results for "Yu-Li Lin"
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Journal Article
Vitamin K and vascular calcification in chronic kidney disease: An update of current evidence
Vascular calcification, characterized by calcium deposition in the intimal and medial layers of the arterial wall, is frequently encountered in patients with chronic kidney disease (CKD) and leads to an enhanced risk of adverse cardiovascular (CV) outcomes. However, the underlying complex…
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Assessment of uremic sarcopenia in dialysis patients: An update
Uremic sarcopenia, which is highly prevalent in dialysis patients, leads to an increased risk of adverse outcomes, such as poor quality of life, falls, fracture, hospitalization, and even mortality. Therefore, early detection of uremic sarcopenia is crucial for administering quick and adequate…
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A Novel Application of Serum Creatinine and Cystatin C to Predict Sarcopenia in Advanced CKD
Sarcopenia is highly prevalent in patients with advanced chronic kidney disease (CKD), yet a reliable serum index has not been established. The product of serum creatinine and the estimated glomerular filtration rate based on cystatin C (Cr×eGFRcys) was recently proposed as a sarcopenia index (SI)…
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Sodium-glucose co-transporter 2 inhibitors use and the risks of genital and urinary tract infection: What should we know?
Sodium-glucose co-transporter 2 (SGLT2) inhibitors have convincingly demonstrated efficacy in reducing cardiovascular (CV) and renal complications in patients with diabetes mellitus, chronic kidney disease, and heart failure. However, their use is also linked to the concern of some adverse events…
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Endothelial dysfunction in chronic kidney disease: Mechanisms, biomarkers, diagnostics, and therapeutic strategies
Endothelial cells regulate vascular tone, blood flow, coagulation, and inflammation, with heterogeneous populations serving specific roles throughout the body. In the kidney, endothelial cells maintain vascular integrity and function, contribute to filtration, and support other renal structures…
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Gut-derived uremic toxins and cardiovascular health in chronic kidney disease
Uremic toxins (UTs) are bioactive compounds that accumulate in chronic kidney disease (CKD) due to impaired renal clearance, exacerbating disease progression and cardiovascular (CV) complications. These toxins originate from endogenous metabolism, gut microbiota, and dietary intake and include…
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Targeting large middle molecules: Clinical implications of expanded hemodialysis in hemodialysis care
End-stage kidney disease (ESKD) presents a major clinical burden, with maintenance hemodialysis (HD) patients facing high cardiovascular mortality and impaired quality of life (QoL). Despite advances from low-flux to high-flux HD and the introduction of hemodiafiltration (HDF), clearance of large…
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A Pythagorean Fuzzy TOPSIS Method Based on Novel Correlation Measures and Its Application to Multiple Criteria Decision Analysis of Inpatient Stroke Rehabilitation
The complex nature of the realistic decision-making process requires the use of Pythagorean fuzzy (PF) sets which have been shown to be a highly promising tool capable of solving highly vague and imprecise problems. Multiple criteria decision analysis (MCDA) methods within the PF environment are…
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Association of serum fibroblast growth factor 21 levels with skeletal muscle mass and mortality in chronic hemodialysis patients
Background/purpose: Fibroblast growth factor 21 (FGF21) is a hormone that modulates metabolic pathways, which acts as a myokine under metabolic stress. We aimed to explore the association of serum FGF21 levels with skeletal muscle mass and mortality in patients on hemodialysis (HD). Methods…
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Effect of Forchlorfenuron Treatment on the Storage Performance and Mineral Elements of Kiwifruits and Correlation Analysis
This study sought to clarify the residue degradation pattern of forchlorfenuron (CPPU) in kiwifruits and its effects on the mineral elements and storage quality of the fruit. Kiwifruits ‘Miliang No. 1’ were applied with CPPU at concentrations of 5, 10, and 20 mg/L at 25 days after flowering, and…
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p63 and p73 Transcriptionally Regulate Genes Involved in DNA Repair
The p53 family activates many of the same genes in response to DNA damage. Because p63 and p73 have structural differences from p53 and play distinct biological functions in development and metastasis, it is likely that they activate a unique transcriptional network. Therefore, we performed a…
Also available at: DOAJ
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Processes and outcomes of diabetes mellitus care by different types of team primary care models
Background: Team care improves processes and outcomes of care, especially for patients with complex medical conditions that require coordination of care. This study aimed to compare the processes and outcomes of care provided to older patients with diabetes by primary care teams comprised of only…
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Improved Topic Sentiment Model with Word Embedding Based on Gaussian Distribution
In recent years,the topic sentiment model as an important research in the field of unsupervised learning,has been used in text topic mining and sentiment analysis.However,Weibo has brought some challenges to the topic sentiment model because of its short text and in complete structure.Therefore,the…
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Journal Article
Risk of cardiovascular events after initiation of long-acting bronchodilators in patients with chronic obstructive lung disease: A population-based study
Objectives: Long-acting bronchodilators are mainstay treatment for moderate to severe chronic obstructive pulmonary disease. A growing body of evidence indicates an increased risk of cardiovascular events upon initiation of these medications. We hypothesize that this risk is higher in patients with…
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Journal Article
Serum Fibroblast Growth Factor 21 Level Is Associated with Aortic Stiffness in Patients on Maintenance Hemodialysis
Background. Fibroblast growth factor 21 (FGF-21) is a hormone that regulates glucose and lipid metabolism. High serum FGF-21 levels are associated with carotid atherosclerosis and coronary artery disease. This cross-sectional study aimed to assess the relationship between serum FGF-21 levels and…
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Association of serum intact parathyroid hormone levels with sarcopenia in patients undergoing peritoneal dialysis
ObjectiveSarcopenia is highly prevalent in patients undergoing peritoneal dialysis (PD), contributing to adverse clinical outcomes. Animal models suggest that parathyroid hormone (PTH) induces muscle wasting through adipose tissue browning. However, the relationship between PTH dysregulation and…
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Serum P-Cresyl Sulfate Level Is an Independent Marker of Peripheral Arterial Stiffness as Assessed Using Brachial-Ankle Pulse Wave Velocity in Patients with Non-Dialysis Chronic Kidney Disease Stage 3 to 5
p-Cresyl sulfate (PCS) is a uremic toxin that causes cardiovascular injury and progression in patients with chronic kidney disease (CKD). Peripheral arterial stiffness (PAS) as measured using the brachial-ankle pulse wave velocity (baPWV) is considered a valuable predictor of cardiovascular event…
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The Association between Serum Adiponectin Levels and Endothelial Function in Non-Dialysis-Dependent Chronic Kidney Disease Patients
Adiponectin is the richest human circulating adipokine with anti-inflammatory, antioxidant, and insulin-sensitizing effects. We evaluated the association between serum adiponectin levels and endothelial function in chronic kidney disease (CKD) patients, obtaining fasting blood samples from 130…
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Negative correlation of serum adiponectin level with peripheral artery occlusive disease in hemodialysis patients
Objective: Adiponectin is a fat-derived hormone that secretes exclusively by adipocytes and has antiatherosclerotic effects. Peripheral arterial occlusive disease (PAOD) is associated with an increased risk of death in hemodialysis (HD) patients. The aim of this study was to evaluate the…