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The interplay between cytokines, inflammation, and antioxidants: mechanistic insights and therapeutic potentials of various antioxidants and anti-cytokine compounds
Cytokines regulate immune responses essential for maintaining immune homeostasis, as deregulated cytokine signaling can lead to detrimental outcomes, including inflammatory disorders. The antioxidants emerge as promising therapeutic agents because they mitigate oxidative stress and modulate…
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Ethical and Bias Considerations in Artificial Intelligence/Machine Learning
As artificial intelligence (AI) gains prominence in pathology and medicine, the ethical implications and potential biases within such integrated AI models will require careful scrutiny. Ethics and bias are important considerations in our practice settings, especially as an increased number of…
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Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial
Abstract There is a pressing need for allogeneic chimeric antigen receptor (CAR)-immune cell therapies that are safe, effective and affordable. We conducted a phase 1/2 trial of cord blood-derived natural killer (NK) cells expressing anti-CD19 chimeric antigen receptor and interleukin-15…
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KDIGO 2024 Clinical Practice Guideline for the management of LUPUS NEPHRITIS
This article is published as part of a supplement sponsored by Kidney Disease: Improving Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of the authors and do not necessarily reflect the opinions or recommendations of the International Society of Nephrology or…
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Advancements in CO2 capture by absorption and adsorption: A comprehensive review
In the face of escalating global climate challenges, effective carbon dioxide (CO₂) capture techniques remain at the forefront of mitigating anthropogenic greenhouse gas emissions. This comprehensive review elucidates the latest advancements in CO₂ capture, emphasizing two predominant…
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A Survey on Graph Neural Networks for Time Series: Forecasting, Classification, Imputation, and Anomaly Detection
Time series are the primary data type used to record dynamic system measurements and generated in great volume by both physical sensors and online processes (virtual sensors). Time series analytics is therefore crucial to unlocking the wealth of information implicit in available data. With the…
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The Early Data Release of the Dark Energy Spectroscopic Instrument
Abstract The Dark Energy Spectroscopic Instrument (DESI) completed its 5 month Survey Validation in 2021 May. Spectra of stellar and extragalactic targets from Survey Validation constitute the first major data sample from the DESI survey. This paper describes the public release of those spectra…
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RETRACTED ARTICLE: The economic commitment of climate change
Abstract Global projections of macroeconomic climate-change damages typically consider impacts from average annual and national temperatures over long-time horizons. Here, we utilize recent empirical findings from more than 1600 regions worldwide over the past 40 years to project sub-national…
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Next-Generation Green Hydrogen: Progress and Perspective from Electricity, Catalyst to Electrolyte in Electrocatalytic Water Splitting
Green hydrogen from electrolysis of water has attracted widespread attention as a renewable power source. Among several hydrogen production methods, it has become the most promising technology. However, there is no large-scale renewable hydrogen production system currently that can compete with…
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Empowering student self‐regulated learning and science education through ChatGPT : A pioneering pilot study
In recent years, AI technologies have been developed to promote students' self‐regulated learning (SRL) and proactive learning in digital learning environments. This paper discusses a comparative study between generative AI‐based (SRLbot) and rule‐based AI chatbots (Nemobot) in a 3‐week science…
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Band gap tuning of perovskite solar cells for enhancing the efficiency and stability: issues and prospects
The intriguing optoelectronic properties, diverse applications, and facile fabrication techniques of perovskite materials have garnered substantial research interest worldwide. Their outstanding performance in solar cell applications and excellent efficiency at the lab scale have already been…
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Cultural bias and cultural alignment of large language models
Culture fundamentally shapes people's reasoning, behavior, and communication. As people increasingly use generative artificial intelligence (AI) to expedite and automate personal and professional tasks, cultural values embedded in AI models may bias people's authentic expression and contribute to…
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Fe-S dually modulated adsorbate evolution and lattice oxygen compatible mechanism for water oxidation
Simultaneously activating metal and lattice oxygen sites to construct a compatible multi-mechanism catalysis is expected for the oxygen evolution reaction (OER) by providing highly available active sites and mediate catalytic activity/stability, but significant challenges remain. Herein, Fe and S…
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Inclination towards entrepreneurship among university students: an empirical study of Malaysian university students
This study investigates the inclination towards entrepreneurship among university students in the northern region of the Peninsular Malaysia. Specifically, it aims to examine the relationship between entrepreneurship education and inclination towards entrepreneurship. The influence of demographic…
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Validation of biomarkers of aging
The search for biomarkers that quantify biological aging (particularly ‘omic’-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the evaluation of interventions promoting healthy aging and longevity…
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Generative AI in Medical Practice: In-Depth Exploration of Privacy and Security Challenges
As advances in artificial intelligence (AI) continue to transform and revolutionize the field of medicine, understanding the potential uses of generative AI in health care becomes increasingly important. Generative AI, including models such as generative adversarial networks and large language…
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Literatura e Sociedade
O presente artigo tem como objetivo investigar como a realidade social se transforma em elementos estéticos na estrutura e na forma das personagens e do enredo do conto A caligrafia de Deus, do autor Márcio Souza. Para tanto, a análise parte da correlação estabelecida entre Literatura e Sociedade…
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Salmonellosis: An Overview of Epidemiology, Pathogenesis, and Innovative Approaches to Mitigate the Antimicrobial Resistant Infections
Salmonella is a major foodborne pathogen and a leading cause of gastroenteritis in humans and animals. Salmonella is highly pathogenic and encompasses more than 2600 characterized serovars. The transmission of Salmonella to humans occurs through the farm-to-fork continuum and is commonly linked to…
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A small and vigorous black hole in the early Universe
Abstract Several theories have been proposed to describe the formation of black hole seeds in the early Universe and to explain the emergence of very massive black holes observed in the first thousand million years after the Big Bang 1–3 . Models consider different seeding and accretion scenarios…
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