17 results for "Li-Rong Wang"

Protocol to identify functional doppelgängers and verify biomedical gene expression data using doppelgangerIdentifier

Li Rong Wang; Xiuyi Fan; Wilson Wen Bin Goh

STAR Protocols, Vol. 3 No. 4 · 2022 · English · DOAJ Scopus

…details on the use and execution of this protocol, please refer to Wang et al. (2022). : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.

Doppelgänger spotting in biomedical gene expression data

Li Rong Wang; Xin Yun Choy; Wilson Wen Bin Goh

iScience, Vol. 25 No. 8 · 2022 · English · DOAJ Scopus

Summary: Doppelgänger effects (DEs) occur when samples exhibit chance similarities such that, when split across training and validation sets, inflates the trained machine learning (ML) model performance. This inflationary effect causes misleading confidence on the deployability of the model. Thus…

Exploiting the similarity of dissimilarities for biomedical applications and enhanced machine learning.

Mohammad Neamul Kabir; Li Rong Wang; Wilson Wen Bin Goh

PLoS Computational Biology, Vol. 21 No. 1 · 2025 · English · DOAJ Scopus

The "similarity of dissimilarities" is an emerging paradigm in biomedical science with significant implications for protein function prediction, machine learning (ML), and personalized medicine. In protein function prediction, recognizing dissimilarities alongside similarities provides a more…

Effect of Phosphoinositide 3-kinase/Protein Kinase B Signaling Pathway on Cell Apoptosis during Chilled Storage of Tan Sheep Meat

ZHANG Qian, LUO Ruiming, CHEN Xueyan, LI Rong, WANG Jinxia, HU Lijun

Shipin Kexue, Vol. 45 No. 9 · 2024 · Chinese · DOAJ Scopus

The hindleg meat of Tan sheep was injected postmortem with the phosphoinositide 3-kinase (PI3K) inhibitor LY294002 at a concentration of 10 μmol/L and stored at 4 ℃. After 0, 2, 4, 6 and 8 days, the protein expression of PI3K and protein kinase B (AKT) was analyzed by sodium dodecyl…

Refined Risk Assessment of Rainstorm-Induced Flood Disasters Based on Hazard-Specific Terrain Weighting

LIU Zhen, ZHAO Liang, WANG Li-rong, WANG Sha, ZHANG Su-yun, SHEN Lu-ming, LI Wei-min

长江科学院院报, Vol. 43 No. 6 · 2026 · Chinese · DOAJ

[Objective] Addressing the increasing demands for disaster prevention and mitigation，it is essential not only to enhance the accuracy of rainstorm forecasting but also to assess in advance the potential disaster-causing risks posed by rainstorms. In contrast to evaluation models that rely on…

The first case of Francisella novicida infection in Taiwan: bacteraemic pneumonia in a haemodialysis adult

Hao-En Jan; Chin-Shiang Tsai; Nan-Yao Lee et al.

Emerging Microbes and Infections, Vol. 11 No. 1 · 2022 · English · DOAJ Scopus

Tularaemia is a zoonotic disease caused by Francisella tularensis (F. tularensis). Human infection is rare and can be life-threatening. F. tularensis subsp. novicida used to be a subspecies of F. tularensis, is now considered a different species, F. novicida. Though less virulent, F. novicida can…

Germplasm and molecular breeding in horticultural crops

Jun WU, Prof.; Qing-mei GUAN, Prof.; Li-rong WANG, Prof. et al.

Journal of Integrative Agriculture, Vol. 22 No. 11 · 2023 · English · DOAJ Scopus

The predictive role of systemic immune-inflammation index on futile recanalization in acute ischemic stroke with mechanical thrombectomy

Huan Liu; Ying-Jie Li; Li-Jun Jia et al.

World Neurosurgery: X, Vol. 28 · 2025 · English · DOAJ Scopus

Background and purpose: Futile recanalization (FR) occurs in patients who achieve successful vessel recanalization but still have a poor prognosis. The aim of this study was to explore the association between systemic immune-inflammation index (SII) and futile recanalization following mechanical…

Predictors of futile recanalization after endovascular treatment of acute ischemic stroke

Li-Rong Wang; Bing-Hu Li; Qi Zhang et al.

BMC Neurology, Vol. 24 No. 1 · 2024 · English · DOAJ Scopus

Abstract Objective Endovascular therapy (EVT) is the most successful treatment for patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO) in the anterior circulation. However, futile recanalization (FR) seriously affects the prognosis of these patients. The aim of this study…

Association of free fatty acid receptor 2 expression in peripheral blood monocytes with carotid atherosclerosis

Li-Jun Jia; Li-Rong Wang; Sen Zhou et al.

European Journal of Medical Research, Vol. 30 No. 1 · 2025 · English · DOAJ Dropped by Scopus 2024

Abstract Purpose To investigate the relationship between free fatty acid receptor 2 (FFAR2) expression in peripheral blood monocytes and carotid atherosclerosis (CAS). Methods Between November 2023 and June 2024, individuals who underwent carotid ultrasound in the inpatient or outpatient settings…

Mechanism of human chorionic gonadotropin in endometrial receptivity via the miR‐126‐3p/PI3K/Akt/eNOS axis

Wei Wang; Liang Ge; Li‐Li Zhang et al.

Kaohsiung Journal of Medical Sciences, Vol. 39 No. 5 · 2023 · English · DOAJ Scopus

Abstract Human chorionic gonadotropin (hCG) might affect endometrial receptivity, exerting integral roles in embryo implantation. This study explored the action of hCG in endometrial receptivity via the miR‐126‐3p/PIK3R2/PI3K/Akt/eNOS axis. The embryo implantation dysfunction (EID) mouse models…

Predictive role of pre-thrombolytic hs-CRP on the safety and efficacy of intravenous thrombolysis in acute ischemic stroke

Xu-Dong Cheng; Duo-Zi Wang; Qi Zhang et al.

BMC Neurology, Vol. 23 No. 1 · 2023 · English · DOAJ Scopus

Abstract Purpose To investigate the predictive role of pre-thrombolytic high sensitivity C-reactive protein (hs-CRP) on the safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke (AIS). Methods Patients with AIS who underwent intravenous thrombolysis with recombinant…

Evaluating Chain-of-Thought reasoning in large language models for thyroid ultrasound interpretation: a dual-information approach

Yu-Tong Zhang; Si-Yi Wu; Dong Zhang et al.

Frontiers in Artificial Intelligence, Vol. 9 · 2026 · English · DOAJ Scopus

ObjectiveTo assess whether reasoning-capable large language models (LLMs) can accurately interpret both qualitative and quantitatively encoded ultrasound features of thyroid nodules within the ACR-TIRADS framework and improve diagnostic reliability.MethodsThis retrospective study analyzed thyroid…

A Competency Framework for Medical AI Education: Mixed Methods Study

Chang Cai; Gaoxia Zhu; Shang-Ming Zhou et al.

JMIR Medical Education, Vol. 12 · 2026 · English · DOAJ Scopus

Abstract BackgroundAlthough artificial intelligence (AI) is increasingly adopted in health care, clinicians face barriers, including insufficient understanding, limited trust, and challenges in interpreting AI outputs. Existing frameworks, such as the United Nations Educational, Scientific and…

Predictive Role of Pre-Thrombolytic Neutrophil-Platelet Ratio on Hemorrhagic Transformation After Intravenous Thrombolysis in Acute Ischemic Stroke

Xu-Dong Cheng BD; Chun-Xi Zhang BD; Qi Zhang BD et al.

Clinical and Applied Thrombosis/Hemostasis, Vol. 30 · 2024 · English · DOAJ Scopus

To investigate the predictive role of the neutrophil-platelet ratio (NPR) before intravenous thrombolysis (IVT) on hemorrhagic transformation (HT) in patients with acute ischemic stroke (AIS). AIS patients treated with IVT without endovascular therapy between June 2019 and February 2023 were…

Tumor-Associated Autoantibodies Anti-p53 is Associated with Poor Prognosis in Patients with Lung Adenocarcinoma

Jing K; Ouyang L; Cai J et al.

Cancer Management and Research, Vol. Volume 17 No. Issue 1 · 2025 · English · DOAJ Scopus

Keying Jing, Libo Ouyang, Jun Cai, Peiming Zheng, Gang Li, Rong Wang Department of Clinical Laboratory, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, People’s Republic of ChinaCorrespondence: Rong Wang, Email wangrong36602010@163.comPurpose: There is a…

Shatai Heji Mitigates Sjögren Disease-Induced Xerostomia by Regulating AQP5, NF-κB, and p38 MAPK Signaling Pathwaysaff

Liu F; Chen J; Gong C et al.

Drug Design, Development and Therapy, Vol. Volume 19 No. Issue 1 · 2025 · English · DOAJ Scopus

Fangbin Liu,* Jiyuan Chen,* Chunai Gong,* Minyan Chen, Gang Yang, Chun Chen, Ru Yao, Shengnan Li, Rong Wang, Yongfang Yuan Department of Pharmacy, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China*These authors…