12 hasil untuk "Adam Collison"

Change in exhaled nitric oxide during peanut challenge is related to severity of reaction

Elizabeth Percival; Rani Bhatia; Kahn Preece dkk.

Allergy, Asthma & Clinical Immunology, Vol. 16 No. 1 · 2020 · Inggris · DOAJ Scopus

Abstract Background Peanut allergy affects 3% of Australian children and has a higher risk of anaphylaxis than most food allergies. Predicting who is likely to develop anaphylaxis is still an inexact science. The fraction of exhaled nitric oxide (FeNO) shows promise as a biomarker involved in…

Association between active tobacco use during pregnancy and infant respiratory health: a systematic review and meta-analysis

Billie Bonevski; Gillian Sandra Gould; Joerg Mattes dkk.

BMJ Open, Vol. 10 No. 9 · 2020 · Inggris · DOAJ Scopus

Objective To evaluate what is known about active tobacco use during pregnancy and the association with infant respiratory health.Design Systematic review and meta-analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.Data sources MEDLINE, EMBASE, Cochrane…

Early Sensory and Temperament Features in Infants Born to Mothers With Asthma: A Cross-Sectional Study

Carly A. Mallise; Vanessa E. Murphy; Linda E. Campbell dkk.

Frontiers in Psychology, Vol. 12 · 2021 · Inggris · DOAJ Scopus

Maternal asthma in pregnancy is associated with an increased risk of adverse perinatal outcomes. Adverse perinatal outcomes may result in poorer infant developmental outcomes, such as temperament and sensory difficulties. This study aimed to (1) assess differences in temperament and sensory…

Epigenetic changes associated with disease progression in a mouse model of childhood allergic asthma

Adam Collison; Jessica S. Siegle; Nicole G. Hansbro dkk.

Disease Models & Mechanisms, Vol. 6 No. 4 · 2013 · Inggris · DOAJ Scopus

SUMMARY Development of asthma in childhood is linked to viral infections of the lower respiratory tract in early life, with subsequent chronic exposure to allergens. Progression to persistent asthma is associated with a Th2-biased immunological response and structural remodelling of the airways…

Children With Asthma Have Impaired Innate Immunity and Increased Numbers of Type 2 Innate Lymphoid Cells Compared With Healthy Controls

Banafshe Hosseini; Bronwyn S. Berthon; Malcolm R. Starkey dkk.

Frontiers in Immunology, Vol. 12 · 2021 · Inggris · DOAJ Scopus

BackgroundAsthma is the most frequent cause of hospitalisation among children; however, little is known regarding the effects of asthma on immune responses in children.ObjectiveThe present study aimed to evaluate cytokine responses of peripheral blood mononuclear cells (PBMCs), PBMC composition and…

Inhibiting AKT Phosphorylation Employing Non-Cytotoxic Anthraquinones Ameliorates T H 2 Mediated Allergic Airways Disease and Rhinovirus Exacerbation

Caio Cesar de Souza Alves; Adam Collison; Luke Hatchwell dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

Background: Severe asthma is associated with T helper (TH) 2 and 17 cell activation, airway neutrophilia and phosphoinositide-3-kinase (PI3K) activation. Asthma exacerbations are commonly caused by rhinovirus (RV) and also associated with PI3K-driven inflammation. Anthraquinone derivatives have…

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Modifiable Factors Impacting Risk of Allergic Rhinitis in Young Children: A Prospective Cohort Study

Angela Zheng; Vanessa E. Murphy; Megan E. Jensen dkk.

International Journal of Pediatrics, Vol. 2026 · 2026 · Inggris · DOAJ Scopus

Research training curriculum and projects undertaken by medical students in Australia and New Zealand

Joanne Hart; Adam Collison; Jon Cornwall dkk.

BMC Medical Education, Vol. 25 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background Research training is vital to medical education, providing students with essential skills for their future evidence-based practice. Most medical programs worldwide include opportunities for students to implement projects. However, gaps remain in understanding how research…

Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models

Alane Blythe C. Dy; Jason Girkin; Antonella Marrocco dkk.

Respiratory Research, Vol. 24 No. 1 · 2023 · Inggris · DOAJ Scopus

Abstract Background Rhinovirus (RV) infection of airway epithelial cells triggers asthma exacerbations, during which airway smooth muscle (ASM) excessively contracts. Due to ASM contraction, airway epithelial cells become mechanically compressed. We previously reported that compressed human…

Clinical and lung function outcomes in a cohort of children with severe asthma

Patricia de Gouveia Belinelo; Aleisha Nielsen; Bernadette Goddard dkk.

BMC Pulmonary Medicine, Vol. 20 No. 1 · 2020 · Inggris · DOAJ Scopus

Abstract Background Uncontrolled severe asthma in children is burdensome and challenging to manage. This study aims to describe outcomes in children with uncontrolled severe asthma managed in a nurse-led severe asthma clinic (SAC). Methods This retrospective analysis uses data collected from…

Early-life lung function deficits partially explain the link between maternal asthma and bronchiolitis or asthma in offspring

Peter G Gibson; Peter D Sly; Sven Schulzke dkk.

BMJ Open Respiratory Research, Vol. 13 No. 1 · 2026 · Inggris · DOAJ Scopus

Background Maternal asthma during pregnancy is associated with an increased risk of bronchiolitis and asthma in offspring, but the mechanisms remain poorly understood. We aimed to assess whether impaired postnatal infant lung function independently influences the risk of bronchiolitis and asthma in…