62 hasil untuk "Athanasios Zikopoulos"

p38β - MAPK11 and its role in female cancers

Periklis Katopodis; Rachel Kerslake; Athanasios Zikopoulos dkk.

Journal of Ovarian Research, Vol. 14 No. 1 · 2021 · Inggris · DOAJ Scopus

Abstract Background The p38MAPK family of Mitogen Activated Protein Kinases are a group of signalling molecules involved in cell growth, survival, proliferation and differentiation. The widely studied p38α isoform is ubiquitously expressed and is implicated in a number of cancer pathologies, as are…

Interplay Between mTOR and Hippo Signaling in the Ovary: Clinical Choice Guidance Between Different Gonadotropin Preparations for Better IVF

Kyriaki Papageorgiou; Eirini Mastora; Athanasios Zikopoulos dkk.

Frontiers in Endocrinology, Vol. 12 · 2021 · Inggris · DOAJ Scopus

One of the most widely used types of assisted reproduction technology is the in vitro fertilization (IVF), in which women undergo controlled ovarian stimulation through the administration of the appropriate hormones to produce as many mature follicles, as possible. The most common hormone…

Functional association between telomeres, oxidation and mitochondria

Efthalia Moustakli; Athanasios Zikopoulos; Prodromos Sakaloglou dkk.

Frontiers in Reproductive Health, Vol. 5 · 2023 · Inggris · DOAJ Scopus

Prior research has substantiated the vital role of telomeres in human fertility. Telomeres are prerequisites for maintaining the integrity of chromosomes by preventing the loss of genetic material following replication events. Little is known about the association between sperm telomere length and…

Methotrexate treatment of very high β-HCG ectopic pregnancy on previous cesarean scar: A case report

Athanasios Zikopoulos; Themistoklis Loukopoulos; Apostolia Galani dkk.

Radiology Case Reports, Vol. 18 No. 11 · 2023 · Inggris · DOAJ Dikeluarkan Scopus 2024

Ectopic pregnancy in a previous caesarean scar is a rare, potentially life-threatening situation that can cause massive bleeding and uterine rupture. Clinical symptoms can range from vaginal bleeding with or without pain, to uterine rupture with hypovolemic shock. Early diagnosis is possible by…

Paternal Contributions to Recurrent Pregnancy Loss: Mechanisms, Biomarkers, and Therapeutic Approaches

Aris Kaltsas; Athanasios Zikopoulos; Vladimir Kojovic dkk.

Medicina, Vol. 60 No. 12 · 2024 · Inggris · DOAJ Scopus

Background and Objectives: Recurrent pregnancy loss (RPL) affects numerous couples worldwide and has traditionally been attributed mainly to maternal factors. However, recent evidence highlights significant paternal influences on pregnancy viability and outcomes. This review aims to comprehensively…

Omental metastases from uveal melanoma—An interesting intraoperative omental pattern appearance

Sofoklis Stavros; Athanasios Zikopoulos; Anastasios Potiris dkk.

Clinical Case Reports, Vol. 12 No. 9 · 2024 · Inggris · DOAJ Dikeluarkan Scopus 2021

Key Clinical Message Uveal melanomas represent approximately 5% of all human melanomas. Omental metastases are often diagnosed as secondary metastatic sites and only a few cases have been described as the first single manifestation of distant metastasis. In this case image, we illustrate the…

Reproductive Health in Women with Major β-Thalassemia: Evaluating Ovarian Reserve and Endocrine Complications

Vasileios Tsilionis; Efthalia Moustakli; Stefanos Dafopoulos dkk.

Metabolites, Vol. 14 No. 12 · 2024 · Inggris · DOAJ Scopus

Thalassemia is an autosomal recessive hereditary chronic hemolytic anemia characterized by a partial or complete deficiency in the synthesis of alpha- or beta-globin chains, which are essential components of adult hemoglobin. Mutations in the globin genes lead to the production of unstable globin…

Dietary and Lifestyle Interventions to Mitigate Oxidative Stress in Male and Female Fertility: Practical Insights for Infertility Management—A Narrative Review

Efthalia Moustakli; Athanasios Zikopoulos; Periklis Katopodis dkk.

Metabolites, Vol. 15 No. 6 · 2025 · Inggris · DOAJ Scopus

Background/Objectives: Infertility in both men and women can be significantly influenced by oxidative stress (OS), which occurs due to an imbalance between reactive oxygen species (ROS) and the body’s antioxidant defenses. In women, OS disrupts oocyte maturation, implantation, and the viability of…

Correction to: Transvaginal closure of urinary bladder opening and Mitrofanof technique in a neurologically impaired female with chronic indwelling catheter: a case presentation

Athanasios Zachariou; Minas Paschopoulos; Aris Kaltsas dkk.

BMC Urology, Vol. 22 No. 1 · 2022 · Inggris · DOAJ Scopus

Nyctalopia during pregnancy due to vitamin A deficiency after bariatric sleeve gastrectomy: A case report

Eleftherios Anastasakis; Anastasios Anastasakis; Athina A. Samara dkk.

Clinical Case Reports, Vol. 12 No. 9 · 2024 · Inggris · DOAJ Dikeluarkan Scopus 2021

Key Clinical Message Herein, we report a rare case of nyctalopia diagnosed in the first trimester of pregnancy due to vitamin A deficiency as a result of a bariatric gastrectomy. Low serum vitamin A levels establish the diagnosis and the patient was treated with oral vitamin A supplements…

Platelet-Rich Plasma (PRP) in Reproductive Medicine: A Critical Review of PRP Therapy in Low-Reserve and Premature Ovarian Insufficiency

Efthalia Moustakli; Anastasios Potiris; Athanasios Zikopoulos dkk.

Biomedicines, Vol. 13 No. 5 · 2025 · Inggris · DOAJ Scopus

Background: Intraovarian platelet-rich plasma (PRP) has emerged as a novel intervention at the intersection of reproductive medicine and regenerative biology. As women with diminished ovarian reserve (DOR), poor response to stimulation, or premature ovarian insufficiency (POI) seek fertility…

The Silent Threat to Women’s Fertility: Uncovering the Devastating Effects of Oxidative Stress

Aris Kaltsas; Athanasios Zikopoulos; Efthalia Moustakli dkk.

Antioxidants, Vol. 12 No. 8 · 2023 · Inggris · DOAJ Scopus

Oxidative stress (OS), which arises through an imbalance between the formation of reactive oxygen species (ROS) and antioxidant defenses, plays a key role in the pathophysiology of female infertility, with the latter constituting just one of a number of diseases linked to OS as a potential cause…

The Influence of Sexually Transmitted Bacteria and Human Papillomavirus on Sperm Parameters: Data from a Preliminary Study

Maria Samara; Eleni Thodou; Christina Messini dkk.

Medicina, Vol. 62 No. 5 · 2026 · Inggris · DOAJ Scopus

Background and Objectives: The microbiome plays a pivotal role in male infertility, with distinct microbial species exerting both beneficial and deleterious effects on reproductive function. Sexually transmitted bacteria and several viruses, including human papillomavirus (HPV), have been…

Uterine Arteries Resistance in Pregnant Women with Gestational Diabetes Mellitus, Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, and Uncomplicated Pregnancies

Christos Chatzakis; Makarios Eleftheriades; Eleftheria Demertzidou dkk.

Biomedicines, Vol. 11 No. 12 · 2023 · Inggris · DOAJ Scopus

Background: The examination of the uterine arteries using Doppler in the first trimester of pregnancy serves as a valuable tool for evaluating the uteroplacental circulation. Diabetes mellitus is associated with altered placental implantation and pregnancy-related pathologies, such as preeclampsia…

Obesity and Pregnancy: Impact on Childbirth Timing, Delivery Mode, and Maternal Recovery: An Update

Angeliki Gerede; Maria Danavasi; Sofoklis Stavros dkk.

Medical Sciences, Vol. 13 No. 3 · 2025 · Inggris · DOAJ Scopus

This review explores the impact of maternal obesity on pregnancy outcomes, emphasizing its significant global health challenge and profound implications for both mothers and infants. It influences the timing and mode of childbirth, elevating the risk of conditions like hypertensive disorders…

Hyperemesis in Pregnancy: Complications and Treatment

Angeliki Gerede; Sofoklis Stavros; Efthalia Moustakli dkk.

Medical Sciences, Vol. 13 No. 3 · 2025 · Inggris · DOAJ Scopus

Background: Hyperemesis gravidarum (HG) is the leading cause of hospitalization during early pregnancy, affecting approximately 0.3–3% of pregnancies. It represents the most severe end of the nausea and vomiting in pregnancy (NVP) spectrum and is associated with substantial maternal morbidity and…

The Impact of Endocrine Disruptors on the Female Genital Tract Microbiome: A Narrative Review

Efthalia Moustakli; Themos Grigoriadis; Anastasios Potiris dkk.

Life, Vol. 15 No. 8 · 2025 · Inggris · DOAJ Scopus

Background/Objectives: Endocrine disruptors (EDs) are xenobiotic chemicals that disrupt hormone signaling and homeostasis within the human body. Accumulative evidence proposes that EDs could affect systemic hormone balance and local microbial communities, including the female genital tract (FGT)…

Empty Follicle Syndrome: Current Therapeutic Approaches and the Role of Triggering Agents in Assisted Reproductive Technology

Sofoklis Stavros; Athanasios Zikopoulos; Stefanos Dafopoulos dkk.

Medical Sciences, Vol. 14 No. 3 · 2026 · Inggris · DOAJ Scopus

The hallmark feature of empty follicle syndrome (EFS) is failure to retrieve oocytes from apparently mature follicles despite adequate ovarian stimulation and appropriate ovulation triggering. Although considered uncommon, with a reported prevalence ranging from 0.2% to 7%, EFS may have a profound…

Melatonin and Mitochondrial Redox Homeostasis in Reproduction: Mechanistic Links Between Circadian Signaling and Fertility Outcomes

Sofoklis Stavros; Panagiotis Christopoulos; Stefanos Dafopoulos dkk.

Biology, Vol. 15 No. 13 · 2026 · Inggris · DOAJ Scopus

The pineal gland regulates circadian physiology through the periodic production of melatonin (MLT). In addition to its established role as a chronobiotic agent, MLT regulates redox homeostasis and mitochondrial physiology. Mitochondria and redox-active molecules, particularly reactive oxygen…

Metabolomics-Driven Insights into Biomarkers for Poor Ovarian Response: A Narrative Review

Anastasios Potiris; Sofoklis Stavros; Eleni Alyfanti dkk.

Biomedicines, Vol. 13 No. 1 · 2025 · Inggris · DOAJ Scopus

Poor ovarian response (POR) remains a significant challenge in the field of assisted reproductive technology (ART), as the quantity and quality of oocytes retrieved directly influence embryo implantation, clinical pregnancy, and live birth rates. Metabolomics has become a valuable tool for…