9 results for "Dylan Baker"
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Journal Article
A Fishy Situation: Hand Infection due to Mycobacterium marinum Mistaken for Giant Cell Tumor
Mycobacterium marinum is an acid-fast bacterium (AFB) associated with exposure to water and aquatic species. When inoculated, infection can result in nodular cutaneous lesions. In the absence of detailed history or culture data, these nodular skin lesions can be mistaken for noninfectious…
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Journal Article
Case series of retinal vein occlusions showing early recovery using oral -methylfolate
This case series describes the aggregate rate of recovery in five consecutive subjects (six eyes) with retinal vein occlusion (RVO) who received l -methylfolate and other vitamins via Ocufolin ® , a medical food. Subjects were followed for 10–33 months by a single ophthalmologist. Ocufolin ® was…
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Journal Article Full text
Effects of Phycosphere Bacteria on Their Algal Host Are Host Species-Specific and Not Phylogenetically Conserved
Phytoplankton is fundamental to life on Earth. Their productivity is influenced by the microbial communities residing in the phycosphere surrounding algal cells. Expanding our knowledge on how algal-bacterial interactions affect algal growth to more hosts and bacteria can help elucidate general…
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Journal Article
Variation in resource competition traits among Microcystis strains is affected by their microbiomes
Abstract Freshwater harmful algal blooms are often dominated by Microcystis, a phylogenetically cohesive group of cyanobacteria marked by extensive genetic and physiological diversity. We have previously shown that this genetic diversity and the presence of a microbiome of heterotrophic bacteria…
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Journal Article
Development of an automated 3D high content cell screening platform for organoid phenotyping
The use of organoid models in biomedical research has grown substantially since their inception. As they gain popularity among scientists seeking more complex and biologically relevant systems, there is a direct need to expand and clarify potential uses of such systems in diverse experimental…
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Journal Article
Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma
Patients with locally advanced and metastatic urothelial carcinoma have a low survival rate (median 15.7 months, 13.1–17.8), with only a 23% response rate to monotherapy treatment with anti-PDL1 checkpoint immunotherapy. To identify new therapeutic targets, we profiled the immune regulatory…
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Journal Article
Sex differences in lower urinary tract biology and physiology
Abstract Females and males differ significantly in gross anatomy and physiology of the lower urinary tract, and these differences are commonly discussed in the medical and scientific literature. However, less attention is dedicated to investigating the varied development, function, and biology…
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Journal Article
Strategies for implementing long‐acting cabotegravir for PrEP in US clinics serving Black women: interim healthcare provider findings from the EBONI study
Abstract Introduction Long‐acting cabotegravir (CAB LA) is the first LA agent approved for HIV pre‐exposure prophylaxis. EBONI (NCT05514509) is a Phase 4 implementation study evaluating the implementation of CAB LA delivery to Black cis‐ and transgender (cis‐and‐trans) women in clinics located in…
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Journal Article
p21-senescent cells drive pancreatic islet dysfunction through targetable paracrine signaling in type 2 diabetes
Cellular senescence is an irreversible stress response, which leads to loss of cellular function and remodeling of the cellular secretory profile. In humans, pancreatic β cells undergo cellular senescence during the progression to type 2 diabetes (T2D). However, the mechanism linking β cell…