42 hasil untuk "Li-yu Lee"
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Artikel Jurnal
A case of renal cell carcinoma metastasizing to invasive ductal breast carcinoma
Tumor-to-tumor metastasis is an uncommon but well-documented phenomenon. We present a case of a clear cell renal cell carcinoma (RCC) metastasizing to an invasive ductal carcinoma (IDC) of the breast. A 74-year-old woman with a past history of clear cell RCC status after radical nephrectomy…
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Artikel Jurnal
Successful Management of Repeated Oligometastatic Squamous Cell Carcinoma of the Mouth Floor with Metastasectomy and Maintenance Tegafur-plus-uracil: A Case Report
This case report describes a patient with poorly differentiated squamous cell carcinoma (PD SqCC) of the mouth floor, staged as pT4aN0M0. The initial treatment comprised surgical resection followed by adjuvant concurrent chemoradiotherapy. The patient subsequently experienced metastatic recurrence…
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Artikel Jurnal Teks lengkap
Oncocytic Lipoadenoma: A Rare Case of Parotid Gland Tumor and Review of the Literature
Oncocytic lipoadenoma is a rare tumor, with only 18 cases having been reported since the first in 1998. We encountered a case of oncocytic lipoadenoma presenting as a slowly growing parotid mass in a 71-year-old man. This tumor is characteristically comprised of a mixture of oncocytes and…
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Artikel Jurnal
A case report of breast cancer in silicone-injected breasts diagnosed by an emerging technique of contrast-enhanced mammography-guided biopsy
BackgroundBreast cancer in silicone-injected breasts is often obscured in conventional mammography and sonography. Contrast-enhanced magnetic resonance imaging (CE-MRI) is an optimal modality for cancer detection. This case report demonstrates the use of contrast-enhanced spectral mammography…
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Artikel Jurnal Teks lengkap
Clinical Outcomes of Patients with Oral Cavity Squamous Cell Carcinoma and Retropharyngeal Lymph Node Metastasis Identified by FDG PET/CT
Purpose: Retropharyngeal lymph node (RPLN) metastasis is an uncommon finding in patients with oral cavity squamous carcinoma (OSCC). We sought to investigate the clinical outcomes, clinicopathological characteristics, and the priority of treatment with curative intent in OSCC patients with RPLN…
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Artikel Jurnal
Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses
Abstract Background Radiotherapy is an indispensable treatment modality in head and neck cancer (HNC), while radioresistance is the major cause of treatment failure. The aim of this study is to identify a prognostic molecular signature associated with radio-resistance in HNC for further clinical…
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Artikel Jurnal
MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44
Abstract Cancer stem cells preferentially acquire the specific characteristics of stress tolerance and high mobility, allowing them to progress to a therapy-refractive state. To identify a critical molecule to regulate cancer stemness is indispensable to erratically cure cancer. In this study, we…
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Artikel Jurnal
Computed Tomography‐Measured Minimum Fascia‐Tumor Distance for Parotid Tumor Location and Facial Palsy Prediction
Abstract Objective To assess the diagnostic performance of CT‐measured minimum fascia‐tumor distance (MFTD) for predicting parotid tumor location and its association with postoperative facial nerve function. Study Design Retrospective cohort. Setting Referral hospital. Methods This retrospective…
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Artikel Jurnal Teks lengkap
Priority of Fibular Reconstruction in Patients with Oral Cavity Cancer Undergoing Segmental Mandibulectomy
Background: The fibula osteoseptocutaneous free flap is generally used for segmental mandibular reconstructions following resection of oral cavity squamous cell carcinoma (OSCC). However, less complex reconstructions may be feasible for patients with predicted poor survival. Herein, we sought to…
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Artikel Jurnal Teks lengkap
Postoperative Concomitant Chemoradiotherapy Improved Treatment Outcomes of Patients with Oral Cavity Cancer with Multiple-Node Metastases but No Other Major Risk Factors
Purpose: To investigate the results of postoperative radiotherapy (PORT) for the treatment of pathologic N2b/c squamous cell carcinoma of the oral cavity (OSCC). Materials and Methods: This study reviewed cancer registry data collected in our hospital from 1998 to 2009 with the following inclusion…
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Artikel Jurnal Teks lengkap
DSG3 Facilitates Cancer Cell Growth and Invasion through the DSG3-Plakoglobin-TCF/LEF-Myc/Cyclin D1/MMP Signaling Pathway
Desmoglein 3 (DSG3) is a component of the desmosome, which confers strong cell-cell adhesion. Previously, an oncogenic function of DSG3 has been found in head neck cancer (HNC). Here, we investigated how this molecule contributes to the malignant phenotype. Because DSG3 is associated with…
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Artikel Jurnal
Immunohistological analysis of stress-induced phosphoprotein 1 in ovarian cancer patients with low serum cancer antigen 125 levels
Objective: Stress-induced phosphoprotein 1 (STIP1) was recently identified as a potential tumor marker for human ovarian cancer. This study further evaluates the usefulness of STIP1 in ovarian tumor patients with normal CA125 serum levels. Materials and Methods: STIP1 and CA125 were…
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Artikel Jurnal
A domain knowledge enhanced yield based deep learning classifier identifies perineural invasion in oral cavity squamous cell carcinoma
BackgroundPerineural invasion (PNI), a form of local invasion defined as the ability of cancer cells to invade in, around, and through nerves, has a negative prognostic impact in oral cavity squamous cell carcinoma (OCSCC). Unfortunately, the diagnosis of PNI suffers from a significant degree of…
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Artikel Jurnal
Maintenance tegafur-plus-uracil after adjuvant concurrent chemoradiotherapy may improve outcome for resected oral cavity squamous cell carcinoma with extranodal extension
ObjectivesTo evaluate whether tegafur-uracil maintenance (UFTm) following postoperation adjuvant cisplatin-based concurrent chemoradiotherapy (CCRT) may reduce distant metastasis in patients with resected oral cavity squamous cell carcinoma (OSCC) with pathologic extranodal extension…
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Artikel Jurnal
Comparison between a novel salivary marker and several clinical prognosticators in oral cavity cancer
Abstract Objectives This study aimed to investigate the association between salivary matrix metalloproteinase‐1 (MMP‐1) and clinicopathological parameters of oral cavity squamous cell carcinoma (OSCC) and compare the prognostic efficacy of salivary MMP‐1 and other established circulating markers…
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Artikel Jurnal
Postoperative radiotherapy with or without concurrent chemotherapy for oral squamous cell carcinoma in patients with three or more minor risk factors: a propensity score matching analysis
Abstract Background To investigate the advantage of concurrent chemotherapy with postoperative radiotherapy (RT) of oral squamous cell carcinoma (OSCC) in patients with three or more minor risk factors. Methods Minor risk factors included pT4 disease, pN1 disease, margin ≤ 4 mm, poor…
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Artikel Jurnal
Prognostic impact of extratumoral perineural invasion in patients with oral cavity squamous cell carcinoma
Abstract Purpose Perineural invasion (PNI) is an adverse prognostic factor in patients with oral cavity squamous cell carcinoma (OCSCC). The American Joint Committee on Cancer Staging Manual, eighth edition, introduced a subdivision of PNI into two distinct forms, that is, extratumoral and…