321 hasil untuk "Lin HOU"
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Artikel Jurnal
Immunotherapy and Immune Infiltration in Patients with Clear Cell Renal Cell Carcinoma: A Comprehensive Analysis
On a global scale, renal cell carcinoma (RCC) is the second most common form of cancer and the 10th leading cause of cancer-related deaths. There are about 70% of cases of RCC that are clear cell renal cell carcinomas (ccRCCs). This study explores possible targets for immune therapy in patients…
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Artikel Jurnal
Spinal cord ultrasound stimulation modulates corticospinal excitability in humans
Background: Low-intensity focused ultrasound offers deep tissue penetration and holds promise as a noninvasive tool for neuromodulating brain circuits. However, its effects on neural activity within the human spinal cord remain largely unexplored. Objective: To investigate the effects of spinal…
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Artikel Jurnal Teks lengkap
How long should the fully hillside-closed forest protection be implemented on the Loess Plateau, Shaanxi, China?
Background Restoration of degraded forest ecosystem is crucial for regional sustainable development. To protect the country’s fragile and fragmented environment, the Chinese government initiated an ecological engineering project, the Natural Forest Protection Program, in seventeen provinces in…
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Artikel Jurnal
Current Strategies for Quantitating Fibrosis in Liver Biopsy
Objective: The present mini-review updated the progress in methodologies based on using liver biopsy. Data Sources: Articles for study of liver fibrosis, liver biopsy or fibrosis assessment published on high impact peer review journals from 1980 to 2014. Study Selection: Key articles were selected…
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Therapeutic potential of plant-derived natural products against drug-induced liver injury
Drug-induced liver injury (DILI) is a major cause of drug development failure and post-marketing restrictions. To date, over 1,000 drugs have been reported to cause liver damage, such as acetaminophen, isoniazid, methotrexate, triptolide and so on. However, there are currently no effective…
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Artikel Jurnal
PARylation-centric crosstalk: orchestrating immune evasion and multidrug resistance in ovarian cancer
Post-translational modifications (PTMs) play pivotal roles in ovarian cancer pathogenesis, with poly(ADP-ribosyl)ation (PARylation) serving as a key regulator of DNA repair, immune evasion, and therapeutic resistance. Beyond PARylation, diverse PTM networks—including ubiquitination…
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Temperature sensing based on slow light via stimulated Brillouin scattering in M-shaped few-mode fiber
This study investigates temperature sensing based on slow light generation via stimulated Brillouin scattering in an M-shaped few-mode fiber. The temperature-dependent properties of four optical modes (LP01, LP11, LP21, and LP02) over a range from –20 °C to 80 °C are analyzed using the…
Juga tersedia di: DOAJ
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Identification of trans-eQTLs using mediation analysis with multiple mediators
Abstract Background Mapping expression quantitative trait loci (eQTLs) has provided insight into gene regulation. Compared to cis-eQTLs, the regulatory mechanisms of trans-eQTLs are less known. Previous studies suggest that trans-eQTLs may regulate expression of remote genes by altering the…
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Cerebrospinal fluid metabolites as potential biomarkers for epilepsy: Insights from genome‐wide association studies
Abstract Objectives While metabolic imbalances have been observed in individuals with epilepsy, the direct involvement of specific metabolites in the development of the condition remains underexplored. A comprehensive analysis of the causality between cerebrospinal fluid metabolites (CSF) and…
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Spatial-Variant SAR Range Cell Migration Correction Using Subaperture Strategy
The coupling between range and azimuth dimensions is the main obstacle for highly squinted synthetic aperture radar (SAR) data focusing. Range walk correction (RWC) processing is effective to remove the linear coupling term, but the residual high order range cell migration (RCM) parts are…
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Aesthetic preference recognition of 3D shapes using EEG
Recognition and identification of aesthetic preference is indispensable in industrial design. Humans tend to pursue products with aesthetic values and make buying decisions based on their aesthetic preferences. The existence of neuromarketing is to understand consumer responses toward marketing…
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Integrating Phosphorylation Network with Transcriptional Network Reveals Novel Functional Relationships
Phosphorylation and transcriptional regulation events are critical for cells to transmit and respond to signals. In spite of its importance, systems-level strategies that couple these two networks have yet to be presented. Here we introduce a novel approach that integrates the physical and…
Juga tersedia di: DOAJ
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Leveraging effect size distributions to improve polygenic risk scores derived from summary statistics of genome-wide association studies
Genetic risk prediction is an important problem in human genetics, and accurate prediction can facilitate disease prevention and treatment. Calculating polygenic risk score (PRS) has become widely used due to its simplicity and effectiveness, where only summary statistics from genome-wide…
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Cancer Stem Cells in Tumours of the Central Nervous System in Children: A Comprehensive Review
SIMPLE SUMMARY: Tumours of the central nervous system (CNS) are the most common solid tumours in children. The difficulties in treating this complicated variety of tumours are that they lead to high mortalities. Cancer stem cells (CSCs) are a subgroup of cells found in various kinds of tumours with…
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Myosin Va Participates in Acrosomal Formation and Nuclear Morphogenesis during Spermatogenesis of Chinese Mitten Crab Eriocheir sinensi s
Background: The Chinese mitten crab Eriocheir sinensis belongs to the Class Crustacea, Decapoda, Brachyura. The spermatozoon of this species is of aflagellated type, it has a spherical acrosome surrounded by the cup-shaped nucleus, which are unique to brachyurans. For the past several decades…
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Artikel Jurnal
Efficient agrobacterium-mediated transformation of Shiraia bambusicola and activation of a specific transcription factor for hypocrellin production
Shiraia bambusicola, as a well-known medicinal and edible macro-fungus, is generally located on the branches of bamboo and plays an important role in herbal treatment. Furthermore, the natural products from its fruiting bodies, hypocrellins, are attracting increasing amounts of attention due to…
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Artikel Jurnal Teks lengkap
Three new species and a new combination of Triblidium
Triblidiaceae (Rhytismatales) currently consists of two genera: Triblidium and Huangshania. Triblidium is the type genus and is characterised by melanized apothecia that occur scattered or in small clusters on the substratum, cleistohymenial (opening in the mesohymenial phase), inamyloid…