87 hasil untuk "Linwei Li"
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Artikel Jurnal
Single-cell RNA sequencing in diffuse large B-cell lymphoma: tumor heterogeneity, microenvironment, resistance, and prognostic markers
Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous malignancy with challenges in treatment resistance and relapse. Single-cell RNA sequencing (scRNA-seq) has provided important insights into tumor heterogeneity, microenvironment interactions, resistance mechanisms, and prognostic…
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The structural difference between strong and fragile liquids
A structural order parameter for disordered configurations is defined, based, not on local topologies, but on the degree of local restraint imposed on each atom. This restraint parameter provides a clear distinction between a strong liquid (SiO2) and a fragile liquid (a binary Lennard-Jones…
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Artikel Jurnal
Therapeutic targeting of VEGF and/or TGF-β to enhance anti-PD-(L)1 therapy: The evidence from clinical trials
Normalizing the tumor microenvironment (TME) is a potential strategy to improve the effectiveness of immunotherapy. Vascular endothelial growth factor (VEGF) and transforming growth factor (TGF)-β pathways play an important role in the development and function of the TME, contributing to the…
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Hyperspectral Anomaly Detection via Merging Total Variation Into Low-Rank Representation
Anomaly detection (AD) aiming to locate targets distinct from the surrounding background spectra remains a challenging task in hyperspectral applications. The methods based on low-rank decomposition utilize the inherent low-rank characteristic of hyperspectral images (HSIs), which has attracted…
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Association between imaging parameter changes and triangular fibrocartilage complex injury after distal radius fractures
Abstract Background Triangular fibrocartilage complex (TFCC) injury is a frequent soft tissue injury that has been observed to accompany distal radius fractures (DRFs) with concomitant changes in radiologic parameters. The aim of this study was to investigate the relevance of distal radial…
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Artikel Jurnal
Poloxamer-based hydrogel with EGCG and rhEGF for diabetic foot ulcer treatment
Abstract A thermosensitive hydrogel dressing was developed for the healing of diabetic foot ulcers (DFUs) using Epigallocatechin gallate (EGCG) and recombinant human epidermal growth factor (rhEGF). Hyaluronic acid (HA), poloxamer 407 (P407), and pectin (PE) were used to form the sol-gel transition…
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Artikel Jurnal
AQUARIUM_HB: a bioinformatics pipeline for human blood circular RNA analysis
Accurately identifying and quantifying human blood circular RNAs (circRNAs) from RNA-seq data is a critical bioinformatics challenge in biomarker discovery for human diseases. In this study, we present AQUARIUM-HB, a comprehensive bioinformatics pipeline for identifying, quantifying, annotating…
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Artikel Jurnal Teks lengkap
Assessing the Relationship between Prosocial Behavior and Well-Being: Basic Psychological Need as the Mediator
Previous research has established a positive link between prosocial behavior (PB) and psychological well-being. However, limited studies have explored the relationship between PB and well-being (WB), particularly among vocational students. Furthermore, the underlying mechanisms, including mediating…
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Artikel Jurnal
Poly[[bis(μ2-6-methylpyrazin-2-carboxylato-κ3N1,O:N4)copper(II)] dihydrate]
In the title compound, {[Cu(C6H5N2O2)2]·2H2O}n, the CuII ion (site symmetry overline{1}) is coordinated by two N,O-bidentate ligands and two N-monodentate ligands in a distorted CuO2N4 octahedral geometry. Each anion acts as a bridge between two cations, thus forming a two-dimensional…
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Artikel Jurnal
Targeting the secretory autophagy–extracellular vesicle interface: fate decisions and translational opportunities
Autophagy preserves cellular homeostasis through lysosomal degradation, but its machinery also participates in extracellular release. This creates a pharmacological problem: changing autophagy or extracellular vesicle (EV) output can alter intracellular disposal, inflammatory signaling and…
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Artikel Jurnal Teks lengkap
Enhanced MPPT in Permanent Magnet Direct-Drive Wind Power Systems via Improved Sliding Mode Control
Addressing the challenges of significant speed overshoot, stability issues, and system oscillations associated with the sliding mode control (SMC) strategy in maximum power point tracking (MPPT) for permanent magnet synchronous wind power systems, this paper introduces a fuzzy sliding mode control…
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Artikel Jurnal Teks lengkap
Enhancing Concurrent Emergency Response: Joint Scheduling of Emergency Vehicles on Freeways with Tailored Heuristic
Scheduling decisions for concurrent emergency response (CER) across multiple disaster sites presents numerous difficulties. The main challenge is to minimize human casualties while taking into account the rationality of resource allocation across different disaster sites. This paper establishes a…
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Artikel Jurnal Teks lengkap
BMP signaling is required for nkx2 . 3 -positive pharyngeal pouch progenitor specification in zebrafish
Pharyngeal pouches, a series of outpocketings that bud from the foregut endoderm, are essential to the formation of craniofacial skeleton as well as several important structures like parathyroid and thymus. However, whether pharyngeal pouch progenitors exist in the developing gut tube remains…
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Artikel Jurnal
Stability analysis of concave slope based on Mein-Larson infiltration model
The slope shape has a significant effect on the surface stress state of slope, and the stress state is closely related to the slope stability. The previous rainfall infiltration model only takes the slope with straight line shape into account, and did not include the slope with curve shape…
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Artikel Jurnal
A pilot human-based study of 68Ga-FAPI-04 PET/CT in staging liver fibrosis and preliminary comparison to FIB-4 and fibroscan
Abstract To explore the potential value of 68Ga-FAPI-04 PET/CT in staging liver fibrosis of patients with chronic liver diseases, and to preliminarily compare its diagnostic performance with Fibroscan and the fibrosis-4 (FIB-4) index. The single-center prospective study enrolled participants with…
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Artikel Jurnal
A Three-Phase to Single-Phase AC-DC-AC Topology Based on Multi-Converter in AC Electric Railway Application
An AC-DC-AC topology based on multi-converter is proposed in this paper. It can match the capacity of the converter for high voltage and large power applications. This structure is not only suitable for solving the power quality problems of electrified railways, but also has its own superiorities…
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Artikel Jurnal
Estimation of mechanical properties of Mg-5Zn-0.5Al-xSn alloy based on virtual crystal approximation
First-principles calculations of multi-component alloys have been studied in detail. Herein, the first-principles calculations of Mg-5Zn-0.5Al-xSn alloys were performed by using the virtual crystal approximation (VCA) method. By calculating the lattice constants and elastic constants of the…
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Artikel Jurnal
NLRP3-mediated pyroptosis in cardiovascular disease: from molecular mechanisms to therapeutic targets
Globally, cardiovascular disease has consistently been the leading cause of death. Its pathogenesis is complex and involves interactions among multiple factors, with inflammatory mechanisms garnering increasing attention. Pyroptosis—pro-inflammatory programmed cell death—is categorized into…
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Artikel Jurnal Teks lengkap
Quantitative Analysis of Risk Coupling Effects in Highway Accidents: A Focus on Primary and Secondary Accidents
Analyzing risk coupling effects in highway accidents provides guidance for preventive decoupling measures. Existing studies rarely explore the differences in risk coupling between primary accidents (PA) and secondary accidents (SA) from a quantitative perspective. This study proposes a method to…
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Artikel Jurnal
Metabolic response prediction using 68Ga-FAPI PET/CT in Non-Hodgkin lymphoma treated with chemotherapy: a pilot study
Abstract Background The aim of this study was to investigate the prediction value of metabolic response using gallium 68 (68Ga) labeled fibroblast-activation protein inhibitor (68Ga-FAPI) positron emission tomography-computed tomography (PET/CT) in Non-Hodgkin lymphoma (NHL) patients receiving…