38 hasil untuk "Mathieu Blot"

Delayed diagnosis of pneumonia in the emergency department: factors associated and prognosis

Maria Bouam; Christine Binquet; Florian Moretto dkk.

Frontiers in Medicine, Vol. 10 · 2023 · Inggris · DOAJ Scopus

IntroductionWhether a delayed diagnosis of community-acquired pneumonia (CAP) in the emergency department (ED) is associated with worse outcome is uncertain. We sought factors associated with a delayed diagnosis of CAP in the ED and those associated with in-hospital mortality.MethodsRetrospective…

CMV Infection and Lymphopenia: Warning Markers of Pneumocystis Pneumonia in Kidney Transplant Recipients

Isabelle Eberl; Christine Binquet; Adrien Guilloteau dkk.

Transplant International, Vol. 37 · 2024 · Inggris · DOAJ Scopus

Pneumocystis pneumonia (PcP) remains life-threatening in kidney transplant recipients (KTR). Our study investigated risk factors one-year before PcP. We conducted a monocentric, case-control study including all KTR at the Dijon University Hospital (France) with a diagnosis of PcP between 2005 and…

Beyond QuantiFERON-TB Results, the Added Value of a Weak Mitogen Response

Marine Jacquier; Christine Binquet; Catherine Manoha dkk.

Frontiers in Medicine, Vol. 9 · 2022 · Inggris · DOAJ Scopus

IntroductionWhile QuantiFERON-TB gold (QFT) is frequently used, little attention is paid to the mitogen response. How it could be impacted and associated with outcomes is poorly known.MethodsRetrospective, case-control study in hospitalized patients who underwent QFT testing in two hospitals…

Do we know enough to recommend corticosteroids in acute respiratory distress syndrome?

Mathieu Blot; Arnaud Salmon-Rousseau; Pascal Chavanet dkk.

Critical Care, Vol. 21 No. 1 · 2017 · Inggris · DOAJ Scopus

Intractable liver abscess and positive string test: Think Klebsiella hypervirulent strain

Jeanne Godon; Sylvia Das-Neves; Thomas Blanchot dkk.

IDCases, Vol. 27 · 2022 · Inggris · DOAJ Scopus

Leukocyte cell population data in patients with cardiac surgery and cardiopulmonary bypass: A potential readily available tool to monitor immunity

Maxime Nguyen; Laure Stiel; Adrien Guilloteau dkk.

Frontiers in Immunology, Vol. 13 · 2023 · Inggris · DOAJ Scopus

PurposeCardiac surgery with cardiopulmonary bypass triggers sterile inflammation that is responsible for post-operative morbidity. Automated flow cytometry devices used for leucocyte count provide cell population data (CPD) regarding fluorescence intensity, size and granularity of leukocytes that…

Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study

Lionel Piroth; Jonathan Cottenet; Anne‐Sophie Mariet dkk.

The Lancet Respiratory Medicine · 2020 · Inggris · OpenAlex Scopus

BACKGROUND: To date, influenza epidemics have been considered suitable for use as a model for the COVID-19 epidemic, given that they are respiratory diseases with similar modes of transmission. However, data directly comparing the two diseases are scarce. METHODS: We did a nationwide retrospective…

The evolution of lung computed tomography findings in COVID-19 from 2020 to 2023: more signs of co-infection

Sabrina Romagny; Thibault Sixt; Florian Moretto dkk.

ERJ Open Research, Vol. 10 No. 1 · 2024 · Inggris · DOAJ Scopus

Addition of daptomycin for the treatment of pneumococcal meningitis: protocol for the AddaMAP study

Lionel Piroth; Mathieu Blot; Pascal Chavanet dkk.

BMJ Open, Vol. 13 No. 7 · 2023 · Inggris · DOAJ Scopus

Background The leading cause of acute bacterial meningitis in adults is Streptococcus pneumoniae. This infection is associated with high rates of mortality and morbidity related, among other factors, to the excessive host response to the pneumococcal lysis. Experimental in vitro and in vivo data…

Mitochondrial alarmins are tissue mediators of ventilator-induced lung injury and ARDS

Serge Grazioli; Irène Dunn-Siegrist; Laure-Anne Pauchard dkk.

PLOS ONE, Vol. 14 No. 11 · 2019 · Inggris · PLOS Scopus

Rationale: Endogenous tissue mediators inducing lung inflammation in the context of ventilator-induced lung injury (VILI) and acute respiratory distress syndrome (ARDS) are ill-defined. Objectives: To test whether mitochondrial alarmins are released during VILI, and are associated with lung…

Juga tersedia di: DOAJ

Infectious endocarditis caused by Elizabethkingia spp.: Two case reports and a literature review

Valentin Colin; Brice Guerpillon; Mathieu Blot dkk.

Journal of Infection and Public Health, Vol. 18 No. 12 · 2025 · Inggris · DOAJ Scopus

We report two cases of Elizabethkingia-related infective endocarditis, highlighting key risk factors such as prosthetic valve replacement. These cases underscore the need to consider endocarditis in the setting of persistent or recurrent bacteremia.Diagnosis proved challenging and required multiple…

Linezolid and atorvastatin impact on pneumonia caused by Staphyloccocus aureus in rabbits with or without mechanical ventilation

Laure-Anne Pauchard; Mathieu Blot; Rémi Bruyere dkk.

PLOS ONE, Vol. 12 No. 11 · 2017 · Inggris · PLOS Scopus

Pneumonia may involve methicillin-resistant Staphylococcus aureus (MRSA), with elevated rates of antibiotics failure. The present study aimed to assess the effect of statins given prior to pneumonia development. Spontaneously breathing (SB) or mechanically ventilated (MV) rabbits with pneumonia…

Juga tersedia di: DOAJ

Pneumococcal meningitis and endotoxemia: A cross-sectional clinical study

Sylvie Nguyen; Jeanne Godon; Jean-Paul Pais de Barros dkk.

PLOS One, Vol. 20 No. 5 · 2025 · Inggris · PLOS Scopus

Introduction: Lipopolysaccharide (LPS) is a major virulence factor during both meningococcal and Haemophilus influenzae meningitis. Pneumococcus does not produce LPS but could be responsible for bacterial digestive translocation as a consequence of sepsis. We addressed this question in the context…

Juga tersedia di: DOAJ

Subacute prosthetic aortic endocarditis caused by Actinotignum schaalii: a rare but destructive pathogen – case report and literature review

Benoit Rallet; Marie-Catherine Morgant; Thibault Lelercq dkk.

BMC Infectious Diseases, Vol. 25 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background Actinotignum schaalii is an emerging urogenital pathogen rarely reported as a cause of endocarditis. Case presentation A 54-year-old man developed recurrent embolic strokes seven and eight years post-Bentall procedure with mechanical aortic valve. Blood cultures grew…

Specific Features of the Coagulopathy Signature in Severe COVID-19 Pneumonia

Mathieu Blot; Emmanuel de Maistre; Abderrahmane Bourredjem dkk.

Frontiers in Medicine, Vol. 8 · 2021 · Inggris · DOAJ Scopus

Rationale: COVID-19 displays distinct characteristics that suggest a unique pathogenesis. The objective of this study was to compare biomarkers of coagulopathy and outcomes in COVID-19 and non-COVID-19 patients with severe pneumonia.Methods: Thirty-six non-COVID-19 and 27 COVID-19…

Combined effects of mesenchymal stromal cells and antibiotic therapy on Enterobacter ventilator-associated pneumonia in rabbits

Marine Jacquier; Caroline Laroye; Danièle Bensoussan dkk.

Respiratory Research, Vol. 27 No. 1 · 2026 · Inggris · DOAJ Scopus

Abstract Background Although mesenchymal stromal cells (MSCs) have shown promising effects in preclinical pneumonia models, their ability to improve outcomes in ventilator-associated pneumonia (VAP) remains poorly explored, despite VAP being a frequent and severe complication in critically ill…

Aspergillus colonisation in severe community-acquired pneumonia: not just a mere colonisation

Valentin Pineau; Adrien Guilloteau; Christine Binquet dkk.

ERJ Open Research, Vol. 9 No. 5 · 2023 · Inggris · DOAJ Scopus