35 hasil untuk "Ping-I Lin"
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Artikel Jurnal
Genetic Pathways Associated With Sleep Problems in Children With Autism Spectrum Disorder
AimsChildren on the autism spectrum are more likely to have sleep problems than non-autistic children. Sleep disturbance may exacerbate emotional and behavioral problems of children on the autism spectrum. A better understanding of the biological mechanisms underlying sleep disturbance provide…
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Identifying Subgroups of Patients With Autism by Gene Expression Profiles Using Machine Learning Algorithms
Objectives: The identification of subgroups of autism spectrum disorder (ASD) may partially remedy the problems of clinical heterogeneity to facilitate the improvement of clinical management. The current study aims to use machine learning algorithms to analyze microarray data to identify clusters…
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Glucagon-like peptide-1 receptor agonists and suicide risk in individuals with diabetes and Cannabis use disorder
Objective: The current study is to examine the association between GLP-1 receptor agonist (GLP-1 RA) use and suicide attempt risk in individuals with type 2 diabetes mellitus (T2DM), including those with comorbid cannabis use disorder (CUD). Methods: We conducted a retrospective study using the…
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Artikel Jurnal Teks lengkap
What have we learned from the time trend of mass shootings in the U.S.?
Little is known regarding the time trend of mass shootings and associated risk factors. In the current study, we intended to explore the time trend and relevant risk factors for mass shootings in the U.S. We attempted to identify factors associated with incidence rates of mass shootings at the…
Juga tersedia di: DOAJ
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Artikel Jurnal
Racial disparities in suicide rates across the united states: a comparative analysis of non-Hispanic Whites and non-Hispanic Blacks
Abstract Background Suicide is a major public health concern in the U.S., with notable racial disparities. Historically, non-Hispanic Whites (NHW) had the highest suicide rates, but recent trends show increasing rates among non-Hispanic Blacks (NHB), particularly youth. Geographic variations may…
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Artikel Jurnal
A Framework-Based Approach to Assessing Mental Health Impacts of the COVID-19 Pandemic on Children and Adolescents
The COVID-19 pandemic has yielded extensive impacts globally in the year of 2020. Although the mental health of children and adolescents may be particularly susceptible to stressors stemming from the pandemic and anti-contagion policies, most ongoing efforts are geared toward curbing the viral…
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Pediatric asthma and autism—genomic perspectives
Abstract High‐throughput technologies, ranging from microarrays to NexGen sequencing of RNA and genomic DNA, have opened new avenues for exploration of the pathobiology of human disease. Comparisons of the architecture of the genome, identification of mutated or modified sequences, and pre‐and…
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Artikel Jurnal
COVID-19 patient transcriptomic and genomic profiling reveals comorbidity interactions with psychiatric disorders
Abstract Psychiatric symptoms are seen in some COVID-19 patients, as direct or indirect sequelae, but it is unclear whether SARS-CoV-2 infection interacts with underlying neuronal or psychiatric susceptibilities. Such interactions might arise from COVID-19 immune responses, from infection of…
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Artikel Jurnal
Arterial lactate level is associated with mortality rate in unscheduled surgical intensive care admissions
Background: Lactate is a widely used biomarker for patients with conditions such as infection or trauma. The value of lactate level in risk stratification is rarely investigated for patients admitted to the surgical Intensive Care Unit (ICU), regardless of diagnosis. Purposes: This study examines…
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Artikel Jurnal
Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder
Abstract Individuals with autism spectrum disorder (ASD) have heterogeneous comorbid conditions. This study examined whether comorbid conditions in ASD are associated with polygenic risk scores (PRS) of ASD or PRS of comorbid conditions in non-ASD specific populations. Genome-wide single nucleotide…
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Artikel Jurnal
Burnout in Australian sport and exercise physicians and registrars: A cross-sectional study
Objectives: To determine the prevalence and factors associated with the risk of burnout among sport and exercise physicians and registrars in Australia. Design: Cross-Sectional Study. Method: Australian based sport and exercise physicians and registrars of the Australasian college of sport and…
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Artikel Jurnal
Attention-deficit hyperactivity disorder in children is related to maternal screen time during early childhood in Taiwan: a national prospective cohort study
Abstract Background It is unclear to familial screen time in early childhood is associated with the subsequent diagnosis of attention-deficit and hyperactivity disorder (ADHD). Our study is to evaluate the association between screen time during early childhood in families and the incidence of ADHD…
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MicroRNAs in metabolic effects with atypical antipsychotics—a scoping review
Background: Metabolic side effects associated with atypical antipsychotics represent a major challenge in the clinical management of schizophrenia, contributing to poor treatment adherence and an increased risk of relapse. MicroRNAs (miRNAs) have emerged as promising diagnostic biomarkers for…
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Artikel Jurnal Teks lengkap
Predicting Aggressive Tendencies by Visual Attention Bias Associated with Hostile Emotions
The goal of the current study is to clarify the relationship between social information processing (e.g., visual attention to cues of hostility, hostility attribution bias, and facial expression emotion labeling) and aggressive tendencies. Thirty adults were recruited in the eye-tracking study that…
Juga tersedia di: DOAJ
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Artikel Jurnal
Co-design of the neurodevelopment assessment scale
IntroductionNeurodevelopmental disorders (NDDs) have high comorbidity rates and shared etiology. Nevertheless, NDD assessment is diagnosis-driven and focuses on symptom profiles of individual disorders, which hinders diagnosis and treatment. There is also no evidence-based, standardized…
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Artikel Jurnal Teks lengkap
Runs of Homozygosity Associated with Speech Delay in Autism in a Taiwanese Han Population: Evidence for the Recessive Model
Runs of homozygosity (ROH) may play a role in complex diseases. In the current study, we aimed to test if ROHs are linked to the risk of autism and related language impairment. We analyzed 546,080 SNPs in 315 Han Chinese affected with autism and 1,115 controls. ROH was defined as an extended…
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Artikel Jurnal Teks lengkap
The Association Between In Utero Exposure to Painkillers and Trajectories of Hyperactivity and Emotional Problems in Children with Autism Compared with Neurotypical Peers
Background/Objectives: In utero exposure to painkillers has raised concerns regarding its potential impact on neurodevelopmental disorders, such as autism spectrum disorder (ASD). This study investigates the association between in utero exposure to painkillers and trajectories of hyperactivity and…
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Artikel Jurnal
Screening for Media Use in the Emergency Department Among Young Australians: Cross-sectional Study
BackgroundResearch on problematic internet use has largely adhered to addiction paradigms, possibly impeding the identification of specific internet behaviors related to psychopathology. This study presents a novel approach to screening for specific problematic internet behaviors by using a new…