33 hasil untuk "Po-Han Lin"
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Artikel Jurnal
Homologous Recombination Deficiency Assays in Epithelial Ovarian Cancer: Current Status and Future Direction
Epithelial ovarian cancer (EOC) patients are generally diagnosed at an advanced stage, usually relapse after initial treatments, which include debulking surgery and adjuvant platinum-based chemotherapy, and eventually have poor 5-year survival of less than 50%. In recent years, promising survival…
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Optimizing coral reef fish larviculture: Significance of iron addition to inorganic fertilization method
Historically, attempts to cultivate marine ornamental fish larvae have been mostly unsuccessful, primarily due to insufficient live feed to meet the diverse requirements of different fish species. This study examined the effects of iron supplementation on the survival of coral reef fish larvae…
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Artikel Jurnal
Clinical dyspnea scenario: Using high-fidelity situation simulation teaching program to evaluate learning effectiveness for clinical junior and pre-clinical nurses
BackgroundConfronting a patient’s breathing difficulties, clinical junior nurses often do not know how to respond, and fail to give proper evaluation and treatment. Sudden changes in the condition make the clinical nursing novices feel pressured, and even, frustrated.ObjectivesThis study aims at…
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Preventive Effects of Fucoidan and Fucoxanthin on Hyperuricemic Rats Induced by Potassium Oxonate
…weeks after the interventions, each group was given potassium oxonate (PO) and hypoxanthine (HX) to induce HUA in all groups except for the control group, and the rats were then sacrificed. Blood and urine were analyzed for biochemical properties, and differences in urine volume were determined…
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Visible Light Induced C-H/N-H and C-X Bonds Reactions
Herein, we report efficient visible light-induced photoredox reactions of C–H/N–H and C–X Bonds. These methods have provided access to varied portfolio of synthetically important γ-ketoesters, azaspirocyclic cyclohexadienones spirocyclohexadienones, multisubstituted benzimidazole derivatives…
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Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) Hull Extract and Active Compounds Inhibit Proliferation of Primary Human Leiomyoma Cells and Protect against Sexual Hormone-Induced Mice Smooth Muscle Hyperproliferation
Uterine leiomyomas, also known as fibroids, are benign neoplasms of the uterus and have a high incidence rate in women of reproductive age. Hysterectomy or myomectomy is the initial treatment, but fibroids will recur if the patient is still exposed to similar risk factors. Therefore, developing new…
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Artikel Jurnal
Transient nuclear inversion by x-ray free electron laser in a tapered x-ray waveguide
The enhancement of x-ray-matter interaction by guiding and focusing radiation from x-ray free electron lasers is investigated theoretically. We show that elliptical waveguides using a cladding material with a high atomic number, such as platinum, can maintain an x-ray intensity of up to three…
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Artikel Jurnal
Whole exome sequencing-based homologous recombination deficiency test for epithelial ovarian cancer
Abstract Background The homologous recombination deficiency (HRD) test is an important tool for identifying patients with epithelial ovarian cancer (EOC) benefit from the treatment with poly(adenosine diphosphate-ribose) polymerase inhibitor (PARPi). Using whole exome sequencing (WES)-based…
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Dynamic Set Planning for Coordinated Multi-Point in B4G/5G Networks
Coordinated Multi-Point (CoMP) is an important technique in B4G/5G networks. With CoMP, multiple base stations can be clustered to compose a cooperating set to improve system throughput, especially for the users in cell edges. Existed studies have discussed how to mitigate overloading scenarios and…
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Artikel Jurnal
Reproductive and environmental exposures and the breast cancer risk in Taiwanese women
Abstract Breast cancer (BC) incidence is increasing around the globe, including in Taiwan, though the cause of the increasing incidence is less clear. We followed up 11,296 Taiwanese females who did not have BC at baseline, and ascertained new invasive BC (N = 351) through data linkage to the…
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Artikel Jurnal
A potential mutation-defined POLE/MMR/TP53 group classifications to stratify BRCA wild type epithelial ovarian cancer
Abstract Background TCGA molecular classification has prognostic value in endometrial cancer, but its application in epithelial ovarian cancer is not clear. Methods We investigated the somatic mutations of POLE, MMR (MLH1, MLH3, MSH2, MSH3, MSH6, PMS1, PMS2) and TP53, in 181 BRCA wild type EOC…
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Circulating Tumor DNA as a Predictive Marker of Recurrence for Patients With Stage II-III Breast Cancer Treated With Neoadjuvant Therapy
BackgroundPatients with stage II to III breast cancer have a high recurrence rate. The early detection of recurrent breast cancer remains a major unmet need. Circulating tumor DNA (ctDNA) has been proven to be a marker of disease progression in metastatic breast cancer. We aimed to evaluate the…
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Artikel Jurnal Teks lengkap
Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport
Stress exposure or increased levels of corticotropin-releasing factor (CRF) induce hippocampal tau phosphorylation (tau-P) in rodent models, a process that is dependent on the type-1 CRF receptor (CRFR1). Although these preclinical studies on stress-induced tau-P provide mechanistic insight for…
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Artikel Jurnal
The plasma proteome and breast cancer risk
Abstract Background Plasma proteins may serve as biomarkers for breast cancer. This study aimed to characterize the blood proteomic signatures of women with a higher risk of breast cancer due to their family history. Methods We conducted a nested case-control study (median followup: 9.8 years)…
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Capsaicin alleviates cisplatin‐induced muscle loss and atrophy in vitro and in vivo
Abstract Background Cisplatin (CP) is a widely used chemotherapeutic drug with subsequent adverse effects on different organs and tissues including skeletal muscle loss and atrophy as the most common clinical symptoms. The molecular mechanism of cisplatin‐induced muscle atrophy is not clearly…
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Acute Q Fever Presenting as Fever of Unknown Origin with Rapidly Progressive Hepatic Failure in a Patient with Alcoholism
We report a case of fulminant acute Q fever presenting as fever of unknown origin with rapidly progressive hepatic failure in a patient with alcoholism. A 51-year-old electrician, who was a habitual drinker, presented with a 2-week history of intermittent high fever, acute hepatomegaly and rapidly…
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Test–Retest Reliability and Random Measurement Error of the Multifactorial Memory Questionnaire in Older Adults With Subjective Memory Complaints
To examine the psychometric properties of the Multifactorial Memory Questionnaire (MMQ) in older adults with subjective memory complaints. The three MMQ subscale (Satisfaction, Ability, and Strategy) was administered twice, with a 3-month interval. The test - retest reliability was examined using…