16 hasil untuk "Shiwei Fu"
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Artikel Jurnal Teks lengkap
Predicting and comparing transcription start sites in single cell populations
The advent of 5’ single-cell RNA sequencing (scRNA-seq) technologies offers unique opportunities to identify and analyze transcription start sites (TSSs) at a single-cell resolution. These technologies have the potential to uncover the complexities of transcription initiation and alternative TSS…
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Morphological structure and properties of bamboo shell fiber
The morphological structure and properties of a natural bamboo shell fiber are analyzed. The fiber has a slight natural convolution morphological structure with a rough surface, and its cross-section has irregular zigzag shape with a hole in the middle, which shows the typical structure of…
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scINSIGHT for interpreting single-cell gene expression from biologically heterogeneous data
Abstract The increasing number of scRNA-seq data emphasizes the need for integrative analysis to interpret similarities and differences between single-cell samples. Although different batch effect removal methods have been developed, none are suitable for heterogeneous single-cell samples coming…
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The magnetization and magnetoresistance of Ni46Mn23Ga22Co5Cu4 shape memory microwires after mechanical training
Magnetization and magnetoresistance are significant for the application of Ni-Mn-Ga shape memory alloys. The Ni46Mn23Ga22Co5Cu4 microwires with excellent mechanical properties were selected to investigate the influence of mechanical training on the microstructure and magnetic properties. The…
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Microstructure and texture in an extruded Mg–Al–Ca–Mn flat-oval tube
In the present study, mechanical property, microstructure and texture of an extruded Mg–1.0Al–1.5Ca–1.0Mn (wt.%) flat-oval tube in both the flat and the oval regions were systematically studied. Our results show that there exists a great difference in microstructure and texture between the flat and…
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Hippo dictates signaling for cellular homeostasis and immune defense in Crassostrea hongkongensis hemocytes
IntroductionThe Hippo signaling pathway is an evolutionarily conserved signaling cascade that plays a crucial role in regulating cell proliferation, differentiation, and apoptosis. It has been shown to be a key regulator of cell fate and cellular homeostasis in various immune processes. Despite its…
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Calibration of a Chromatic Confocal Microscope for Measuring a Colored Specimen
In this paper, a color correction method is proposed to improve measurement accuracy for chromatic confocal microscopy (CCM) when measuring a colored specimen. Characteristic curve shifting due to selective reflection from color surfaces was analyzed based on a laboratory CCM system developed by…
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Full‐color‐tunable chiral aggregation‐induced emission fluorophores with tailored propeller chirality and their circularly polarized luminescence
Abstract The regulation of emission color, emission efficiency, and asymmetry factor is of great significance for the real applications of circularly polarized luminescent (CPL) materials. Herein, we develop a modular synthetic strategy toward full‐color‐tunable CPL materials based on chiral…
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Redox-sensitive camptothecin prodrug: A promising drug delivery strategy with ultrahigh drug loading and tunable drug release
Small molecular drugs play a critical role in cancer therapy but face challenges like poor solubility, severe side effects, and inefficient delivery. Polymeric micellar-based drug delivery systems show promise but struggle with low drug loading, instability, and premature drug release partly due to…
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Responsive Multivesicular Polymeric Nanovaccines that Codeliver STING Agonists and Neoantigens for Combination Tumor Immunotherapy
Abstract Immune checkpoint blockade (ICB) has significantly advanced cancer immunotherapy, yet its patient response rates are generally low. Vaccines, including immunostimulant‐adjuvanted peptide antigens, can improve ICB. The emerging neoantigens generated by cancer somatic mutations elicit…
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Artikel Jurnal Teks lengkap
Machine Learning-Driven Discovery and Evaluation of Antimicrobial Peptides from Crassostrea gigas Mucus Proteome
Marine antimicrobial peptides (AMPs) represent a promising source for combating infections, especially against antibiotic-resistant pathogens and traditionally challenging infections. However, traditional drug discovery methods face challenges such as time-consuming processes and high costs…
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The complete mitochondrial genome of Silurus grahami Regan, 1907 (Siluriformes: Siluridae), a native catfish in Fuxian Lake
In this study, the whole mitochondrial genome of Silurus grahami was reported to be 16,518 bp in length, including 13 protein-coding genes, two ribosomal RNAs, 22 transfer RNAs, and one control region. The phylogenetic analysis based on 13 protein-coding genes showed that S. grahami was sister to…
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The Effect of Hippocampal Avoidance Whole Brain Radiotherapy on the Preservation of Long-Term Neurocognitive Function in Non-Small Cell Lung Cancer Patients With Brain Metastasis
Whole-brain radiotherapy (WBRT) is the mainstay of therapy in treating cancer patients with brain metastases, but unfortunately, it might also lead to decline in neurocognitive function. This study aims to investigate the preservation of long-term neurocognitive function in patients after…
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Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation
Starvation is the most common physiological challenge for marine bivalves, especially in oligotrophic seas like the South China Sea. Its dominant oyster species, Saccostrea mordax, remains unclear regarding starvation tolerance and underlying mechanisms. Here, we treated S. mordax with starvation…