21 hasil untuk "Sylvain Mathieu"

Prevalence and impact of sleep disorders in osteoarthritis: A systematic review and meta-analysisKeypoints

Sylvain Mathieu; Anne-Christine Rat; Jérémie Sellam

Osteoarthritis and Cartilage Open, Vol. 8 No. 1 · 2026 · Inggris · DOAJ Scopus

Objective: Sleep disorders (SD) are increasingly recognized as a major contributor to the symptom burden of osteoarthritis (OA), yet their epidemiology and clinical impact remain insufficiently characterized. This systematic literature review with meta-analysis aims to quantify the prevalence of SD…

Use of trial register information during the peer review process.

Sylvain Mathieu; An-Wen Chan; Philippe Ravaud

PLoS ONE, Vol. 8 No. 4 · 2013 · Inggris · DOAJ Scopus

INTRODUCTION: Evidence in the medical literature suggests that trial registration may not be preventing selective reporting of results. We wondered about the place of such information in the peer-review process. METHOD: We asked 1,503 corresponding authors of clinical trials and 1,733 reviewers to…

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Osteoarthritis year in review 2024: Epidemiology and therapy

Alice Courties; Inès Kouki; Nadine Soliman dkk.

Osteoarthritis and Cartilage · 2024 · Inggris · OpenAlex Scopus

This "Year in Review" presents a curated selection of research themes and individual studies within the clinical osteoarthritis (OA) field, focusing on epidemiology and therapy. The search was conducted in electronic database MEDLINE from March 4, 2023, to March 31, 2024, specifically targeting…

Individuals’ perceptions and experiences of mHealth for home-based rehabilitation in knee osteoarthritis: A qualitative study

Mathilde Pelletier Visa; Inès Monborne; Charlotte Lanhers dkk.

Osteoarthritis and Cartilage Open, Vol. 8 No. 3 · 2026 · Inggris · DOAJ Scopus

Objective: Individuals with knee osteoarthritis (KOA) rarely continue exercising after discharge from physiotherapy. We aimed to explore barriers and facilitators influencing the use of mHealth for home-based rehabilitation among people with KOA. Design: An inductive qualitative study using…

Efficacy and safety of capsaicin 8% patches: The experience of a rheumatology department

Sylvain Mathieu; Marion Couderc; Marine Beauger dkk.

SAGE Open Medicine, Vol. 13 · 2025 · Inggris · DOAJ Scopus

Background: Capsaicin 8% patches are recommended for the treatment of localized neuropathic pain, which is a frequent reason for rheumatology consultations. Objectives: This study aimed to evaluate the efficacy and safety of capsaicin 8% used in our Rheumatology Department. Design: Single-center…

Features and management of osteoarthritis from the perspective of individuals with osteoarthritis: A systematic review of qualitative studies

Sylvain Mathieu; Alice Courties; Céline Mathy dkk.

Osteoarthritis and Cartilage Open, Vol. 7 No. 2 · 2025 · Inggris · DOAJ Scopus

Objective: To enable person-centered care, considering beliefs, needs, and priorities of individuals with osteoarthritis (OA) is crucial. Nevertheless, concepts that they consider important are not fully recapitulated in assessment and care. The aim of this study was to clarify how individuals with…

CADOR (Capsaicin in neuropathic-like pain in digital osteoarthritis) study protocol: a multicentre randomised parallel-group trial

Jérémie Sellam; Martin Soubrier; Hubert Marotte dkk.

BMJ Open, Vol. 15 No. 3 · 2025 · Inggris · DOAJ Scopus

Introduction It is common for finger pain in hand osteoarthritis (HOA) to display a neuropathic component. Non-steroidal anti-inflammatory drugs (NSAIDs) and conventional analgesics are not very effective in relieving this neuropathic-like pain. Capsaicin, a compound extracted from chilli peppers…

Pamidronate is ineffective for inflammatory-like low back pain associated with Modic type 1 changes: A double-blind, randomised controlled trialKey points

Martin Soubrier; Charlotte Lanhers; Bruno Pereira dkk.

Osteoarthritis and Cartilage Open, Vol. 8 No. 3 · 2026 · Inggris · DOAJ Scopus

Objective: Modic type 1 (MC-1) vertebral endplate changes are associated with chronic low back pain (LBP) and often reflect an inflammatory process. Pamidronate has demonstrated analgesic effects in conditions involving bone marrow oedema. Our study aimed to evaluate the efficacy of intravenous…

Use of Synofast® in routine rheumatology practice: diagnostic performance and impact on management of an acute arthritis

F. Badaire; C. Lambert; C. Chen Wa dkk.

Advances in Rheumatology, Vol. 65 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background Septic arthritis (SA) is a rare but serious disease. There is no reliable marker for rapid diagnosis. Synofast® is a new device that analyses synovial fluid and can accurately rule out SA within 15 minutes. Objective To evaluate the diagnostic performance of Synofast® in routine…

Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis

Johanna Sigaux; Sylvain Mathieu; Yann Nguyen dkk.

Arthritis Research & Therapy, Vol. 24 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Background Polyunsaturated fatty acid (PUFA) supplementation has been reported to improve disease activity in inflammatory rheumatic diseases (IRDs). However, data are often conflicting and studies insufficiently large to draw conclusions. This systematic literature review and…

Glucocorticoid trajectories over 2 years in patients with rheumatoid arthritis in a real-life setting

Martin Soubrier; Bruno Pereira; Sylvain Mathieu dkk.

RMD Open, Vol. 9 No. 4 · 2023 · Inggris · DOAJ Scopus

Objectives To analyse glucocorticoid (GC) use and trajectories in a real-life cohort of rheumatoid arthritis (RA).Methods Patients with RA included in the longitudinal RCVRIC cohort for initiating or changing biological disease-modifying antirheumatic drugs, were compared for the use of GCs at…

Frequency of irritable bowel syndrome in spondyloarthritis: a multicentric cross-sectional study and meta-analysis

Adeline Ruyssen-Witrand; Thomas Barnetche; Cécile Gaujoux-Viala dkk.

RMD Open, Vol. 10 No. 1 · 2024 · Inggris · DOAJ Scopus

Objective To evaluate the prevalence of symptoms and factors associated with irritable bowel syndrome (IBS) in axial spondyloarthritis (ax-SpA).Methods In a cross-sectional multicentric study, consecutive patients with ax-SpA treated with biologics in five rheumatology departments were asked for…

Decision Tree With Only Two Musculoskeletal Sites to Diagnose Polymyalgia Rheumatica Using [18F]FDG PET-CT

Anthime Flaus; Julie Amat; Nathalie Prevot dkk.

Frontiers in Medicine, Vol. 8 · 2021 · Inggris · DOAJ Scopus

Introduction: The aim of this study was to find the best ordered combination of two FDG positive musculoskeletal sites with a machine learning algorithm to diagnose polymyalgia rheumatica (PMR) vs. other rheumatisms in a cohort of patients with inflammatory rheumatisms.Methods: This retrospective…

Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography in Inflammatory Rheumatism, Particularly Polymyalgia Rheumatica: A Retrospective Study of 222 PET/CT

Julie Amat; Marion Chanchou; Louis Olagne dkk.

Frontiers in Medicine, Vol. 7 · 2020 · Inggris · DOAJ Scopus

Purpose: The objective of this study was to evaluate periarticular FDG uptake scores from 18F-FDG-PET/CT to identify polymyalgia rheumatica (PMR) within a population presenting rheumatic diseases.Methods: A French retrospective study from 2011 to 2015 was conducted. Patients who underwent…

[99mTc]Tc-NTP 15 − 5, a new proteoglycan tracer for functional imaging of joint cartilage: phase I (CARSPECT)

Marion Chanchou; Emilie Thivat; Sylvain Mathieu dkk.

EJNMMI Research, Vol. 15 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background [99mTc]Tc-NTP 15 − 5 showed affinity for joint cartilage proteoglycans on preclinical studies but has not been tested in humans. This phase I trial (CARPECT: NCT04481230) aims to define the optimal of [99mTc]Tc-NTP 15 − 5 injected activity to obtain the best visual contrast of…

The relationship between circulating and tissue biomarkers and OA-related pain: A systematic literature review

Sylvain Mathieu; Liisa Kuhi; Marie Binvignat dkk.

Osteoarthritis and Cartilage Open, Vol. 7 No. 4 · 2025 · Inggris · DOAJ Scopus

Objective: This study aimed to provide an overview of the relationship between osteoarthritis (OA) pain and various fluid biomarkers by conducting a systematic literature review (SLR), to help the development of OA-related pain endotyping. Method: An SLR was conducted, using the PubMed, Embase…

Protocol publication rate and comparison between article, registry and protocol in RCTs

Sylvain Mathieu; Jean-Baptiste Bouillon-Minois; Laurent Renard Triché dkk.

BMC Medical Research Methodology, Vol. 25 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background Increasing transparency in clinical research is crucial to avoid misleading conclusions. Registering clinical trials prior to participant enrolment is mandatory, and the publication of trial protocols could further enhance transparency. However, the impact of protocol…

Brain functional imaging contributions in osteoarthritis-related pain: A viewpoint

Camille Fauchon; Marie Binvignat; Francis Berenbaum dkk.

Osteoarthritis and Cartilage Open, Vol. 7 No. 1 · 2025 · Inggris · DOAJ Scopus

Objective: Neuroimaging investigations are critical to provide a more direct assessment of brain disturbances associated with osteoarthritis (OA)-related pain, and to better understand its pathophysiology to develop new treatment strategies. This viewpoint aims to summarize the importance of the…

Assessment of 99mTc-NTP 15-5 uptake on cartilage, a new proteoglycan tracer: Study protocol for a phase I trial (CARSPECT)

Emilie Thivat; Marion Chanchou; Sylvain Mathieu dkk.

Frontiers in Medicine, Vol. 9 · 2022 · Inggris · DOAJ Scopus

Background99mTc-NTP 15-5 is a SPECT radiotracer targeting proteoglycans (PG), components of the cartilaginous extracellular matrix. Imaging of PGs would be useful for the early detection of cartilage disorders (osteoarthritis, arthritis and chondrosarcoma, Aromatase Inhibitor associated arthralgia…