15 hasil untuk "Tyler Nelson"
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Artikel Jurnal
Laser power optimization for feedforward control of melt pools in laser powder bed fusion
Prior studies have demonstrated that there is a high correlation between uniform melt-pool size and build quality such as consistent microstructure for laser powder bed fusion (PBF-LB/M) additive manufacturing (AM) processes. This paper presents an optimization of laser power to regulate the…
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Artikel Jurnal
Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses
The function of the neuronal synapse depends on the dynamics and interactions of individual molecules at the nanoscale. With the development of single-molecule super-resolution microscopy over the last decades, researchers now have a powerful and versatile imaging tool for mapping the molecular…
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Artikel Jurnal Teks lengkap
Bioinspired Hierarchical Carbon Structures as Potential Scaffolds for Wound Healing and Tissue Regeneration Applications
Engineered bio-scaffolds for wound healing provide an attractive treatment option for tissue engineering and traumatic skin injuries since they can reduce dependence on donors and promote faster repair through strategic surface engineering. Current scaffolds present limitations in handling…
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Artikel Jurnal Teks lengkap
Effect of Electrospun Fiber Mat Thickness and Support Method on Cell Morphology
Electrospun fiber mats (EFMs) are highly versatile biomaterials used in a myriad of biomedical applications. Whereas some facets of EFMs are well studied and can be highly tuned (e.g., pore size, fiber diameter, etc.), other features are under characterized. For example, although substrate…
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Artikel Jurnal
Examining cellular responses to reconstituted antibody protein liquids
Abstract Protein ionic liquids (PIL) are a new class of biologic stabilizers designed to protect the functionality and extend the shelf-life of biotechnological and therapeutic agents making them more readily available, and resistant to austere environments. Protein biorecognition elements such as…
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Artikel Jurnal
The ratio of propylene glycol to glycerol modulates nicotine taste and reward: more glycerol, more reward
BackgroundPropylene glycol (PG) and glycerol (Gly) are odorless tobacco product constituents that act as solvents in electronic cigarette e-liquids and as humectants in oral nicotine products. Little is known about how PG/Gly ratio may affect nicotine’s sensory and rewarding properties. To address…
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Artikel Jurnal
Contractile pericytes determine the direction of blood flow at capillary junctions
Significance Capillaries—the most abundant vessels in the circulatory system—deliver O 2 and nutrients to all cells of the body. In the brain and retina, capillaries also act as a sensory web that detects neuronal activity. Here, we demonstrate that pericytes localized at capillary junctions in a…
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Artikel Jurnal
Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer
Abstract Background The role of the inflammatory milieu in prostate cancer progression is not well understood. Differences in inflammatory signaling between localized and metastatic disease may point to opportunities for early intervention. Methods We modeled PCa disease progression by analyzing…
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Artikel Jurnal
Optical Spectroscopy Reveals Hidden Neutron-capture Elemental Abundance Differences among APOGEE-identified Chemical Doppelgängers
Grouping stars by chemical similarity has the potential to reveal the Milky Way’s evolutionary history. The APOGEE stellar spectroscopic survey has the resolution and sensitivity for this task. However, APOGEE lacks access to strong lines of neutron-capture elements ( Z > 28), which have…
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Synthesizing current knowledge on the ecology, phenology, and cultivation of Vaccinium membranaceum
Societal Impact Statement More than 100 edible native berries grow across Canada's vast territory and are used by over 600 Indigenous Peoples of Canada as a main component of their diet. This research provides critical insights into the ecology, phenology, and cultivation of black huckleberry…
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Artikel Jurnal
Characterization of an engineered live bacterial therapeutic for the treatment of phenylketonuria in a human gut-on-a-chip
Engineered live bacteria could represent a new class of therapeutic treatment for human disease. Here, the authors use a human gut-on-a-chip microfluidics system to characterize an engineered live bacterial therapeutic, designed for the treatment of phenylketonuria, and to construct mathematical…
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Artikel Jurnal
Toxicity assessment of CeO₂ and CuO nanoparticles at the air-liquid interface using bioinspired condensational particle growth
CeO2 and CuO nanoparticles (NPs) are used as additives in petrodiesel to enhance engine performance leading to reduced diesel combustion emissions. Despite their benefits, the additive application poses human health concerns by releasing inhalable NPs into the ambient air. In this study, a…
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Artikel Jurnal
Anxiety, Depression, and Suicidality Among Testicular Cancer Survivors
ABSTRACT Introduction We evaluated the incidence of anxiety, depression, and suicidality amongst TC survivors and the impact of chemotherapy on these outcomes. Methods We conducted a retrospective cohort study of men diagnosed with TC in the United States Veterans Affairs Health System from 1990 to…
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Artikel Jurnal
Metabolic Syndrome Among Testicular Cancer Survivors: Long‐Term Follow‐Up of the Veterans Affairs Health System
ABSTRACT Background The 5‐year survival rate for patients with testicular germ cell tumors (TC) is excellent. However, these survivors are at an increased risk for metabolic syndrome (MetS), a significant source of morbidity and precursor to cardiovascular disease. This study investigates the…
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Artikel Jurnal
Natural History and Risk Stratification of Biochemically Recurrent Prostate Cancer Following Definitive Radiation Therapy
Purpose: Among patients with biochemical recurrent (BCR) prostate cancer following radiation therapy, there is no validated method for identifying those at the highest risk for metastases or death from prostate cancer. We characterized the natural history of BCR after radiation therapy and…