40,148 results
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A review on Quantum Approximate Optimization Algorithm and its variants
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Alzheimer’s disease: insights into pathology, molecular mechanisms, and therapy
Alzheimer's disease (AD), the leading cause of dementia, is characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. This condition casts a significant shadow on global health due to its complex and multifactorial nature. In addition to genetic predispositions…
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A microfluidic platform integrating functional vascularized organoids-on-chip
The development of vascular networks in microfluidic chips is crucial for the long-term culture of three-dimensional cell aggregates such as spheroids, organoids, tumoroids, or tissue explants. Despite rapid advancement in microvascular network systems and organoid technologies, vascularizing…
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Impact of ChatGPT on ESL students’ academic writing skills: a mixed methods intervention study
Abstract This paper presents a study on the impact of ChatGPT as a formative feedback tool on the writing skills of undergraduate ESL students. Since artificial intelligence-driven automated writing evaluation tools positively impact students’ writing, ChatGPT, a generative artificial…
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RETRACTED: A review of history, properties, classification, applications and challenges of natural and synthetic dyes
Natural dyes have been used for centuries for coloring textiles, food, and other materials. Synthetic dyes are particularly popular due to their ease of use, wide range of available colors, and fastness. However, their usage comes with significant environmental and health challenges. In recent…
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Research and application of polypropylene: a review
Polypropylene (PP) is a versatile polymer with numerous applications that has undergone substantial changes in recent years, focusing on the demand for next-generation polymers. This article provides a comprehensive review of recent research in PP and its advanced functional applications. The…
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The Potential Impact of Probiotics on Human Health: An Update on Their Health-Promoting Properties
Probiotics, known to be live microorganisms, have been shown to improve or restore the gut microbiota, which in turn has been linked to improved health. It is believed that probiotics are the modern equivalent of a panacea, with claims that they may treat or prevent different diseases both in…
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Effects of Probiotics on Gut Microbiota: An Overview
The role of probiotics in regulating intestinal flora to enhance host immunity has recently received widespread attention. Altering the human gut microbiota may increase the predisposition to several disease phenotypes such as gut inflammation and metabolic disorders. The intestinal microbiota…
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Wnt/β-catenin signaling pathway in carcinogenesis and cancer therapy
The Wnt/β-catenin signaling pathway plays a crucial role in various physiological processes, encompassing development, tissue homeostasis, and cell proliferation. Under normal physiological conditions, the Wnt/β-catenin signaling pathway is meticulously regulated. However, aberrant activation of…
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Global, regional, and national burden of ischemic stroke, 1990–2021: an analysis of data from the global burden of disease study 2021
Background: Ischemic stroke remains a major contributor to global mortality and morbidity. This study aims to provide an updated assessment of rates in ischemic stroke prevalence, incidence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2021, specifically focusing on including…
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Large Language Models in Medicine: The Potentials and Pitfalls
Large language models (LLMs) are artificial intelligence models trained on vast text data to generate humanlike outputs. They have been applied to various tasks in health care, ranging from answering medical examination questions to generating clinical reports. With increasing institutional…
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Locking the lattice oxygen in RuO2 to stabilize highly active Ru sites in acidic water oxidation
Abstract Ruthenium dioxide is presently the most active catalyst for the oxygen evolution reaction (OER) in acidic media but suffers from severe Ru dissolution resulting from the high covalency of Ru-O bonds triggering lattice oxygen oxidation. Here, we report an interstitial silicon-doping…
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Muscle abnormalities worsen after post-exertional malaise in long COVID
A subgroup of patients infected with SARS-CoV-2 remain symptomatic over three months after infection. A distinctive symptom of patients with long COVID is post-exertional malaise, which is associated with a worsening of fatigue- and pain-related symptoms after acute mental or physical exercise, but…
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Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2024 Update by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)
The critical nature of the microbiology laboratory in infectious disease diagnosis calls for a close, positive working relationship between the physician and the microbiologists who provide enormous value to the health care team. This document, developed by experts in both adult and pediatric…
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Methods for screening and evaluation of antimicrobial activity: A review of protocols, advantages, and limitations
Infectious diseases pose a formidable global challenge, compounded by the emergence of antimicrobial resistance. Consequently, researchers are actively exploring novel antimicrobial compounds as potential solutions. This endeavor underscores the pivotal role of methods employed for screening and…
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ESGO–ESMO–ESP consensus conference recommendations on ovarian cancer: pathology and molecular biology and early, advanced and recurrent disease
The European Society of Gynaecological Oncology, the European Society for Medical Oncology (ESMO) and the European Society of Pathology held a consensus conference (CC) on ovarian cancer on 15-16 June 2022 in Valencia, Spain. The CC panel included 44 experts in the management of ovarian cancer and…
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Applying Lean Principles to Eliminate Project Waste, Maximize Value, Cut Superfluous Steps, Reduce Rework and Focus on Customer Centricity
With increasingly complex demands, dynamic environments, and rapid technology changes defining business landscapes, project management methodologies are prime for disruption. Traditional project models – characterized by rigid, sequential stage-gates and siloed functional groups – struggle with…
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Full-colour 3D holographic augmented-reality displays with metasurface waveguides
Abstract Emerging spatial computing systems seamlessly superimpose digital information on the physical environment observed by a user, enabling transformative experiences across various domains, such as entertainment, education, communication and training 1–3 . However, the widespread adoption of…
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