28 results for "Li-Hong Liu"

Relationship between hypothyroidism and the incidence of gestational diabetes: A meta-analysis

Li-Li Gong; He Liu; Li-Hong Liu

Taiwanese Journal of Obstetrics & Gynecology, Vol. 55 No. 2 · 2016 · English · DOAJ Scopus

Objectives: Hypothyroidism disorders and gestational diabetes are among the most common endocrinopathies during pregnancy. We conducted a meta-analysis to investigate whether hypothyroidism in pregnancy is associated with gestational diabetes risk. Materials and methods: Published literature from…

Model tests on pull-out mechanism of rotary excavation squeezed cast-in-place piles

CHEN Li-hong , LIU Li , ZHANG Zhi-peng

Yantu gongcheng xuebao, Vol. 42 No. S1 · 2020 · Chinese · DOAJ Scopus

Through the indoor small scale model tests, the optimal burial depth position and disc spacing of the bearing plate of the rotary excavated squeezed cast-in-situ piles are further determined, which provides the necessary basis for its application. In the silty clay layer, the 30 mm-pile diameter…

First report of TSR origin minerals filled in anhydrite dissolved pores in southeastern Ordos Basin

Li-hong Liu; Chun-lian Wang; Xing-min Zhao

China Geology, Vol. 2 No. 2 · 2019 · English · DOAJ Scopus

Critical Appraisal of the Quality of Clinical Practice Guidelines for Stress Ulcer Prophylaxis

Zhi-Kang Ye; Ying Liu; Xiang-Li Cui et al.

PLOS ONE, Vol. 11 No. 5 · 2016 · English · PLOS Scopus

Background and Objective: Inappropriate use of stress ulcer prophylaxis (SUP) is common in many hospitals. High-quality clinical practice guidelines (CPGs) produce better patient outcomes and promote cost-effective clinical care. Thus, the objective of this study was to evaluate the quality of CPGs…

Also available at: DOAJ

Network meta-analysis of the efficacy and safety of monoclonal antibodies and traditional conventional dichotomous agents for chronic obstructive pulmonary disease

Yu Xiong; Jia-qiang Hu; Hui-lin Tang et al.

Frontiers in Medicine, Vol. 11 · 2024 · English · DOAJ Scopus

IntroductionMonoclonal antibodies (mAbs) against cytokines and chemokines or their receptors promise to be a potential therapeutic option to address chronic obstructive pulmonary disease (COPD). We aim to provide a comprehensive literature review of the improvement in FEV1 and safety when comparing…

Crystal structure of 1,7,8,9-tetrachloro-4-(2-fluorobenzyl)-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione

Jia-liang Zhong; Jia-wei Hou; Li-hong Liu et al.

Acta Crystallographica Section E: Crystallographic Communications, Vol. 71 No. 1 · 2015 · English · DOAJ Scopus

In the title compound, C17H12Cl4FNO4, the configuration of the cycloalkene skeleton is endo,cis. The benzene ring is twisted by 71.01 (11)° from the attached pyrrolidine ring. In the crystal, one of the methine groups of the fused-ring system forms a weak C—H...O hydrogen bond. The other methine…

(5-Bromo-2-hydroxyphenyl)(4-propylcyclohexyl)methanone

Kang Meng; Miao Cao; Zhuo-Ling An et al.

Acta Crystallographica Section E, Vol. 68 No. 4 · 2012 · English · DOAJ

In the title compound, C16H21BrO2, the cyclohexane ring adopts a chair conformation. The hydroxy and carbonyl groups are involved in an intramolecular O—H...O hydrogen bond. In the crystal, weak C—H...O interactions link the molecules into zigzag chains along [010].

Protective Effects of Akebia Saponin D Against Rotenone-Induced Hepatic Mitochondria Dysfunction

Li-li Gong; Zi-hui Wang; Guang-run Li et al.

Journal of Pharmacological Sciences, Vol. 126 No. 3 · 2014 · English · DOAJ Scopus

Abstract.: Akebia saponin D (ASD) is a typical bioactive triterpenoid saponin obtained from the rhizome of Dipsacus asper Wall. Previous studies have found that ASD has a hepatoprotective effect in a mouse model. The purpose of this paper was to explore the molecular mechanism of the…

Eicosanoid Metabolomic Profile of Remdesivir Treatment in Rat Plasma by High-Performance Liquid Chromatography Mass Spectrometry

Ping Du; Guo-yong Wang; Rui Zhao et al.

Frontiers in Pharmacology, Vol. 12 · 2021 · English · DOAJ Scopus

Remdesivir, a nucleotide analog prodrug, has displayed pharmacological activity against SARS-CoV-2. Recently, eicosanoids are widely involved in regulating immunity and inflammation for COVID-19 patients. Rats were intravenously administered remdesivir at a dose of 5 mg/kg, and series of blood…

Crystal structure of 1,7,8,9-tetrachloro-4-(3,5-dichlorobenzyl)-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione

He Liu; Jia-liang Zhong; Wen-xia Sun et al.

Acta Crystallographica Section E: Crystallographic Communications, Vol. 71 No. 1 · 2015 · English · DOAJ Scopus

In the title compound, C17H11Cl6NO4, the configuration of the cycloalkene skeleton is endo,cis. The benzene ring is twisted by 58.94 (8)° from the attached pyrrolidine ring. Two carbonyl groups play a key role in the crystal packing. A short intermolecular C...O distance of 3.017 (3) Å reveals that…

Ethyl 2-[6-(4-methylbenzoyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]-2-oxoacetate

He Liu; Li-hong Liu; Fu-li Zhang et al.

Acta Crystallographica Section E, Vol. 69 No. 12 · 2013 · English · DOAJ

In the title compound, C25H23NO4, the pyrrolizine ring is approximately planar with an r.m.s deviation from planarity of 0.0053 Å, while the fused dihydropyrrolizine ring adopts an envelope conformation with the C atom connected to two CH2 as the flap. The dihedral angles between the fused ring…

Methyl 3-[(chloromethoxy)carbonyloxy]-7-hydroxycholan-24-oate

Jia-Liang Zhong; Wen-Xia Sun; Fu-Li Zhang et al.

Acta Crystallographica Section E, Vol. 69 No. 7 · 2013 · English · DOAJ

The title compound, C27H43ClO6, is a derivative of ursodeoxycholic acid, in which the OH group at the 3-position is substituted by a chloromethoxycarbonyloxy substituent and the carboxylic acid group at the 24-position is methylated. The A and B rings are cis-fused, while all other rings are…

3,5-Bis(adamantan-1-yl)-1-methoxybenzene

Peng-Fei Li; Jian-Zi Sun; Ling Wang et al.

Acta Crystallographica Section E, Vol. 68 No. 4 · 2012 · English · DOAJ

In title compound, C27H36O, all cyclohexane rings within the adamantyl groups adopt chair conformations. There are no obvious intermolecular hydrogen bonds in the structure, so that van der Waals attractions stabilize the crystal.

Missed Monteggia fractures in children treated by open reduction of the radial head and corrective osteotomy of the ulna

Shu Cao; Zhong-Gen Dong; Li-Hong Liu et al.

Scientific Reports, Vol. 12 No. 1 · 2022 · English · DOAJ Scopus

Abstract Missed Monteggia fractures in children may cause pain, deformity, decreased range of motion, neurological symptoms, and late arthritis of the elbow. Numerous surgical techniques have been advocated to reconstruct missed Monteggia lesions. The purpose of the present study were first to…

Critical Role of E1623 Residue in S3-S4 Loop of Nav1.1 Channel and Correlation Between Nature of Substitution and Functional Alteration

Tao Su; Meng-Long Chen; Li-Hong Liu et al.

Frontiers in Molecular Neuroscience, Vol. 14 · 2022 · English · DOAJ Scopus

Objective: An overwhelming majority of the genetic variants associated with genetic disorders are missense. The association between the nature of substitution and the functional alteration, which is critical in determining the pathogenicity of variants, remains largely unknown. With a novel…

VDR Gene variation and insulin resistance related diseases

Fei-fei Han; Ya-li Lv; Li-li Gong et al.

Lipids in Health and Disease, Vol. 16 No. 1 · 2017 · English · DOAJ Scopus

Abstract Background Vitamin D status may influence the risk of Insulin resistance related diseases such as Type 2 diabetes (T2DM), metabolic syndrome (MetS), and polycystic ovarian syndrome (PCOS). Several studies have assessed vitamin D receptor (VDR) gene polymorphism in relationship with these…

Network pharmacology and molecular simulation suggest potential mechanisms of sorafenib-induced HFSR

Li qian Wang; Si qi Zhang; Ling Guo et al.

Pakistan Journal of Pharmaceutical Sciences, Vol. 39 No. 10 · 2026 · English · DOAJ Scopus

Background: Hand–foot skin reaction (HFSR) is a dose-limiting adverse effect of sorafenib, yet its molecular etiology remains elusive. Objectives: This study investigated the potential targets and pathways of sorafenib-induced HFSR using integrated computational methods. Methods: Network…

Advancing precision tacrolimus therapy: a systems genetics dissection in BXD platform

Wei Zhou; Xin-Bo Wang; Yu-Wei Guo et al.

Frontiers in Immunology, Vol. 17 · 2026 · English · DOAJ Scopus

BackgroundTacrolimus is a core immunosuppressant in organ transplantation, but its narrow therapeutic window and significant pharmacokinetic variability hinder precision dosing. Although CYP3A5-guided strategies have established clinical relevance for tacrolimus initial dose adjustment, they do not…

Factors related to the absorption rate of benign thyroid nodules after image-guided microwave ablation: a 3-year follow-up

Li-Hong Liu; Bei-Bei Yang; Ying Liu et al.

International Journal of Hyperthermia, Vol. 39 No. 1 · 2022 · English · DOAJ Scopus

Purpose To assess the absorption rate and factors related to the development of benign thyroid nodules (BTNs) following image-guided microwave ablation (MWA). Materials and methods This retrospective study reviewed nodule efficacy in patients who underwent MWA of BTNs between January 2016 and…