69 hasil untuk "Li-Qun Zhang"
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Artikel Jurnal
Off-axis biomechanical alterations and related interventions in medial knee osteoarthritis: a mini review
Medial compartment knee osteoarthritis (OA) is the most common form of knee OA and can be influenced by off-axis (frontal and transverse plane) biomechanics. Abnormalities such as varus malalignment, elevated knee adduction moment (KAM), dynamic varus thrust, altered step width, lateral trunk lean…
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Artikel Jurnal
Effect of Stretching of Spastic Elbow Under Intelligent Control in Chronic Stroke Survivors—A Pilot Study
Objective: To assess the short-term effects of strenuous dynamic stretching of the elbow joint using an intelligent stretching device in chronic spastic stroke survivors.Methods: The intelligent stretching device was utilized to provide a single session of intensive stretching to the spastic elbow…
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Artikel Jurnal
MCP extensors respond faster than flexors in individuals with severe-to-moderate stroke-caused impairment: Evidence of uncoupled neural pathways
Damage in the corticospinal system following stroke produces imbalance between flexors and extensors in the upper extremity, eventually leading to flexion-favored postures. The substitution of alternative tracts for the damaged corticospinal tract is known to excessively activate flexors of the…
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Artikel Jurnal
Changes in Muscle Stress and Sarcomere Adaptation in Mice Following Ischemic Stroke
While abnormal muscle tone has been observed in people with stroke, how these changes in muscle tension affect sarcomere morphology remains unclear. The purpose of this study was to examine time-course changes in passive muscle fiber tension and sarcomeric adaptation to these changes post-ischemic…
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Artikel Jurnal
In-Bed Sensorimotor Rehabilitation in Early and Late Subacute Stroke Using a Wearable Elbow Robot: A Pilot Study
Objects: To evaluate the feasibility and effectiveness of in-bed wearable elbow robot training for motor recovery in patients with early and late subacute stroke.Methods: Eleven in-patient stroke survivors (male/female: 7/4, age: 50.7 ± 10.6 years, post-stroke duration: 2.6 ± 1.9 months) received…
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Artikel Jurnal
Effects of Robot-Aided Rehabilitation on the Ankle Joint Properties and Balance Function in Stroke Survivors: A Randomized Controlled Trial
Background: Stroke survivors with impaired control of the ankle due to stiff plantarflexors often experience abnormal posture control, which affects balance and locomotion. Forceful stretching may decrease ankle stiffness and improve balance. Recently, a robot-aided stretching device was developed…
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Artikel Jurnal
EMG-Based Continuous and Simultaneous Estimation of Arm Kinematics in Able-Bodied Individuals and Stroke Survivors
Among the potential biological signals for human-machine interactions (brain, nerve, and muscle signals), electromyography (EMG) widely used in clinical setting can be obtained non-invasively as motor commands to control movements. The aim of this study was to develop a model for continuous and…
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Artikel Jurnal Teks lengkap
MuscleExpert: a semi-automated tool delivering ImageJ-comparable measurements of muscle thickness, area, and quality
Background Most image-analysis software programs were not designed specifically for ultrasound-based measurements, resulting in irrelevant general-purpose features that force users to navigate through multiple menus and making the analysis time-consuming and increasing the likelihood of error. The…
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Artikel Jurnal
Position as Well as Velocity Dependence of Spasticity—Four-Dimensional Characterizations of Catch Angle
We investigated the muscle alterations related to spasticity in stroke quantitatively using a portable manual spasticity evaluator.Methods: Quantitative neuro-mechanical evaluations under controlled passive elbow stretches in stroke survivors and healthy controls were performed in a research…
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Artikel Jurnal
Characterization of the influence of the dominant tract on hand closing post stroke based on the Fugl-Meyer score
Abstract While stroke survivors with moderate or mild impairment are typically able to open their hand at will, those with severe impairment cannot. Abnormal synergies govern the arm and hand in stoke survivors with severe impairment, so hand opening, which is required to overcome the working…
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Artikel Jurnal
Abnormal coordination of upper extremity during target reaching in persons post stroke
Abstract Understanding abnormal synergy of the upper extremity (UE) in stroke survivors is critical for better identification of motor impairment. Here, we investigated to what extent stroke survivors retain the ability to coordinate multiple joints of the arm during a reaching task. Using an…
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Artikel Jurnal
The Oxidoreductase DsbA1 negatively influences 2,4-diacetylphloroglucinol biosynthesis by interfering the function of Gcd in Pseudomonas fluorescens 2P24
Abstract Background The polyketide antibiotic 2,4-diacetylphloroglucinol (2,4-DAPG), produced by Pseudomonas fluorescens 2P24, is positively regulated by the GacS-GacA two-component system. Results Here we reported on the characterization of DsbA1 (disulfide oxidoreductase) as novel regulator of…
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Artikel Jurnal
Experimental evolution of plant rhizobacteria reveals emerging adaptive mutations
ABSTRACT The colonization capability of plant growth-promoting rhizobacteria (PGPRs) in the rhizosphere is essential for their beneficial effects on plant growth, yet the evolutionary processes and adaptive potential of PGPRs in this environment remain underexplored. Here, we established an…
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Artikel Jurnal
In silico and Genetic Analyses of Cyclic Lipopeptide Synthetic Gene Clusters in Pseudomonas sp. 11K1
Pseudomonas sp. 11K1, originally isolated from rhizosphere, possesses inhibitory activity against plant pathogenic fungi and bacteria. Herein, the genome of strain 11K1 was sequenced and subjected to in silico, mutational, and functional analyses. The 11K1 genome is 6,704,877 bp in length, and…
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Artikel Jurnal
Effect of the Monothiol Glutaredoxin GrxD on 2,4-Diacetylphloroglucinol Biosynthesis and Biocontrol Activity of Pseudomonas fluorescens 2P24
Pseudomonas fluorescens 2P24 is a plant root-associated bacterium that suppresses several soilborne plant diseases due to its production of the antibiotic 2,4-diacetylphloroglucinol (2,4-DAPG). The biosynthesis of 2,4-DAPG is controlled by many regulatory elements, including the global regulator of…
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Artikel Jurnal
Regulation of 2,4-diacetylphloroglucinol biosynthesis and biocontrol capacity by the BolA family protein IbaG in Pseudomonas fluorescens 2P24
ABSTRACT The monothiol glutaredoxin GrxD plays an essential role in the biosynthesis of the antibiotic 2,4-diacetylphloroglucinol (2,4-DAPG) and the biocontrol capacity of the soil bacterium Pseudomonas fluorescens 2P24. However, the detailed mechanism underlying GrxD-mediated activation of the…
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Artikel Jurnal
Efflux pump activation confers mupirocin resistance and enhances rhizosphere fitness in Pseudomonas
ABSTRACT Mupirocin (Mup) is a polyketide antibiotic for clinical methicillin-resistant Staphylococcus aureus treatment and agricultural biocontrol, acting by binding to IleRS to inhibit protein synthesis. Here, we demonstrate that Pseudomonas viciae 11K1 acquires resistance to mupirocin not through…
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Artikel Jurnal Teks lengkap
Trefoil Factor 3 as an Endocrine Neuroprotective Factor from the Liver in Experimental Cerebral Ischemia/Reperfusion Injury
Cerebral ischemia, while causing neuronal injury, can activate innate neuroprotective mechanisms, minimizing neuronal death. In this report, we demonstrate that experimental cerebral ischemia/reperfusion injury in the mouse causes upregulation of the secretory protein trefoil factor 3 (TFF3) in the…
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Artikel Jurnal
Role of a Urinary Biomarker in the Common Mechanism of Physical Performance and Cognitive Function
IntroductionHealthy aging is described as a process of developing and maintaining intrinsic abilities, including physical and cognitive functions. Although oxidative stress is a common mechanism shared by loss of muscle strength and dementia, its relationship with decreased physical performance and…
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Artikel Jurnal
Characterization of a novel HLA-A*11:335 allele resulting from a rare interlocus recombination involving HLA-A*11:01:01:01/126 and HLA-H*02:07/14/18 alleles with nanopore sequencing, in a volunteer from the China Marrow Donor Program
Abstract Background The major histocompatibility complex (MHC) in humans includes three classical class I loci (A, B, and C), which are important biomarkers for the transplantation of organs and hematopoietic stem cells. In the MHC, polymorphism is known to be extremely high while interlocus…