22 hasil untuk "Li-Ting Chen"
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Assessing Intervention Effects in the Presence of Missing Scores
Due to repeated observations of an outcome behavior in N-of-1 or single-case design (SCD) intervention studies, the occurrence of missing scores is inevitable in such studies. Approximately 21% of SCD articles published in five reputable journals between 2015 and 2019 exhibited evidence of missing…
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Accounting for baseline trends in intervention studies: Methods, effect sizes, and software
Single-case experimental studies are relevant and important to substantiate the effectiveness of behavioral, clinical, and educational interventions. When a baseline trend is present in intervention studies, it is challenging for researchers to determine, visually or statistically, if an effect is…
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2-(1-Ethyl-5-methoxy-1H-indol-3-yl)-N-(4-methoxyphenyl)-2-oxoacetamide
The title compound, C20H20N2O4, crystallizes with four independent molecules in the asymmetric unit. In the molecules, the dihedral angles between the benzene rings and indole mean planes are 24.5 (1), 22.5 (1), 8.8 (1) and 13.9 (1)°. In the crystal, intermolecular…
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Dihydroartemisinin inhibits LL-37-induced pyroptosis in the human keratinocyte HaCaT
Objective To explore the effect of dihydroartemisinin (DHA) on LL-37-induced pyroptosis in human keratinocyte HaCaT cells. Methods HaCaT cells were divided into control group, model group(40 μg/mL LL-37), DHA low-dose group(DHA-L,40 μg/mL LL-37+10 μmol/L DHA), DHA medium-dose group(DHA-M, 40 μg/mL…
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9-{[4-(Dimethylamino)benzyl]amino}-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3′,4′:6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
In the title compound, C31H34N2O7, the fused tetrahydrofuran and six-membered rings each display an envelope conformation. The dihedral angles between the benzene ring of the benzo[d][1,3]dioxole and the other two benzene rings are 89.68 (3) and 63.38 (2)°. In the crystal, weak…
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A New Dicoumarinyl Ether from the Roots of Stellera chamaejasme L
A new dicoumarinyl ether, 3-hydroxy-6-methoxy-7,7'-dicoumarinyl ether (1), was isolated from the roots of Stellera chamaejasme L, together with the known compound umbelliferone (2). Their structures were determined on the basis of spectroscopic techniques, including IR, NMR, and HR-ESI-MS.
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9-[(2-Chlorobenzyl)amino]-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3′,4′:6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
In the title compound, C29H28ClNO7, the tetrahydrofuran ring and the six-membered ring fused to it both display envelope conformations. The dihedral angles between the plane of the benzene ring of the benzo[d][1,3]dioxole system and the planes of the other two benzene rings are 80.59 (3) and…
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Physical activity awareness and engagement among mining professionals: Implications for safe and healthy workplaces
Mining is a cornerstone of modern industry, and the health and well-being of mining professionals is a priority for industry sustainability. While regular physical activity (PA) participation is key to promoting health and preventing noncommunicable diseases, there is a lack of studies examining…
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Pharmacological and Molecular Docking Investigation of Leaves of Eriobotrya japonica: Antioxidant, Enzyme Inhibition, and Anti-Inflammatory Effects
Leaves of Eriobotrya japonica have long been utilized in traditional Chinese medicine (TCM) for treating pulmonary inflammation and stomach disorders. This study extends their pharmacological applications by evaluating the antioxidant, anti-α-glucosidase, anti-acetylcholinesterase (AChE), and…
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Integration of cognitive behavioral therapy and mobile health applications among university students with depression: a qualitative study
Background Most applications for depression lack comprehensive theoretical integration and qualitative assessments of university students’ needs remain insufficient. Objective This study aimed to explore the needs and experiences of university students with depressive symptoms and develop a…
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Analysis of physicochemical characteristics, sensory attributes and consumer choice preference of commercially available soy sauce with different processes
Using commercially available Cantonese soy sauce, Japanese soy sauce, and traditional Sichuan soy sauce as research subjects, the sensory quality, physicochemical indicators, free amino acids, and organic acids of the 3 types of soy sauce were analyzed. Furthermore, the relationship between these…
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Developing a Silk Fibroin Composite Film to Scavenge and Probe H2O2 Associated with UV-Excitable Blue Fluorescence
A silk fibroin composite film that can simultaneously scavenge and probe H2O2 in situ was developed for possibly examining local concentrations of H2O2 for biomedical applications. A multi-functional composite film (GDES) that consists of graphene oxide (G), a photothermally responsive element that…
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Sex-specific behavioral alterations and underlying molecular mechanisms of zebrafish with environmental-related zinc exposure
Human activities give rise to plenty of environmental zinc accumulation which leads to various health problems in many kinds of organisms. Deleterious effects of zinc contamination on zebrafish have been reported, however, studies associated with sex-specific neurobehavior phenotypes and…
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Iqcg Is Essential for Sperm Flagellum Formation in Mice
Mammalian spermatogenesis comprises three successive phases: mitosis phase, meiosis phase, and spermiogenesis. During spermiogenesis, round spermatid undergoes dramatic morphogenesis to give rise to mature spermatozoon, including the condensation and elongation of nucleus, development of acrosome…
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NGS-based Aspergillus detection in plasma and lung lavage of children with invasive pulmonary aspergillosis
Abstract In immunocompromised pediatric patients, diagnosing invasive pulmonary aspergillosis (IPA) poses a significant challenge. Next-Generation Sequencing (NGS) shows promise for detecting fungal DNA but lacks standardization. This study aims to advance towards clinical evaluation of liquid…
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Integration of multiple lineage measurements from the same cell reconstructs parallel tumor evolution
Summary: Organoid evolution models complemented with integrated single-cell sequencing technology provide a powerful platform to characterize intra-tumor heterogeneity (ITH) and tumor evolution. Here, we conduct a parallel evolution experiment to mimic the tumor evolution process by evolving a…
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Bacterial cell-free DNA profiling reveals the co-elevation of multiple bacteria in newborn foals with suspected sepsis
Summary: Sepsis is the leading cause of death in neonatal foals, yet current diagnostics lack sufficient sensitivity and specificity. Here, we present a foal cell-free DNA (cfDNA) sequencing for bacterial identification (cfFBI) workflow that integrates wet-lab and computational protocols, enabling…