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15 hasil untuk "Sebastian Sanduleanu"

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  1. Artikel Jurnal

    The PANEN nomogram: clinical decision support for patients with metastatic pancreatic neuroendocrine neoplasm referred for peptide receptor radionuclide therapy

    Aviral Singh; Sebastian Sanduleanu; Harshad R. Kulkarni dkk.

    Frontiers in Endocrinology, Vol. 16 · 2025 · Inggris · DOAJ Scopus

    IntroductionPatients with pancreatic neuroendocrine neoplasms (P-NEN) may benefit from peptide receptor radionuclide therapy (PRRT). Prediction of overall survival (OS) using statistical models has the potential to guide treatment decisions. In this study, we have generated a clinicopathological…

  2. Artikel Jurnal Teks lengkap

    Feasibility of GPT-3.5 versus Machine Learning for Automated Surgical Decision-Making Determination: A Multicenter Study on Suspected Appendicitis

    Sebastian Sanduleanu; Koray Ersahin; Johannes Bremm dkk.

    AI, Vol. 5 No. 4 · 2024 · Inggris · DOAJ Scopus

    Background: Nonsurgical treatment of uncomplicated appendicitis is a reasonable option in many cases despite the sparsity of robust, easy access, externally validated, and multimodally informed clinical decision support systems (CDSSs). Developed by OpenAI, the Generative Pre-trained Transformer…

  3. Artikel Jurnal

    A protocol for permissive weight-bearing during allied health therapy in surgically treated fractures of the pelvis and lower extremities

    Guido Meys; Pishtiwan H. S. Kalmet; Sebastian Sanduleanu dkk.

    Journal of Rehabilitation Medicine, Vol. 51 No. 4 · 2019 · Inggris · DOAJ Scopus

    Objective: To optimize rapid clinical recovery and restoration of function and functionality, permissive weight-bearing has been designed as a new aftercare mobilization regimen, within the upper boundary of the therapeutic bandwidth, yet safe enough to avoid overloading. The aim of the present…

  4. Artikel Jurnal

    Deep learning in fracture detection: a narrative review

    Pishtiwan H S Kalmet; Sebastian Sanduleanu; Sergey Primakov dkk.

    Acta Orthopaedica, Vol. 91 No. 2 · 2020 · Inggris · DOAJ Scopus

    Artificial intelligence (AI) is a general term that implies the use of a computer to model intelligent behavior with minimal human intervention. AI, particularly deep learning, has recently made substantial strides in perception tasks allowing machines to better represent and interpret complex…

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  5. Artikel Jurnal Teks lengkap

    From Bedside to Bot-Side: Artificial Intelligence in Emergency Appendicitis Management

    Koray Ersahin; Sebastian Sanduleanu; Sithin Thulasi Seetha dkk.

    Life, Vol. 15 No. 9 · 2025 · Inggris · DOAJ Scopus

    Introduction: Acute appendicitis (AA) is a common cause of abdominal pain that can lead to complications like perforation and intra-abdominal abscesses, increasing morbidity and mortality, often requiring emergency surgery. Nevertheless, appendectomy is performed in up to 95% of uncomplicated…

  6. Artikel Jurnal

    [18F]-HX4 PET/CT hypoxia in patients with squamous cell carcinoma of the head and neck treated with chemoradiotherapy: Prognostic results from two prospective trials

    Sebastian Sanduleanu; Olga Hamming-Vrieze; Frederik W.R. Wesseling dkk.

    Clinical and Translational Radiation Oncology, Vol. 23 · 2020 · Inggris · DOAJ Scopus

    Introduction: The presence of hypoxia in head-and-neck squamous cell carcinoma is a negative prognostic factor. PET imaging with [18F] HX4 can be used to visualize hypoxia, but it is currently unknown how this correlates with prognosis. We investigated the prognostic value of [18F] HX4 PET imaging…

  7. Artikel Jurnal

    Investigating the association between osteopenia and bowel perforation through a multicenter radiologic analysis

    Sebastian Sanduleanu; Koray Ersahin; Jonathan Kottlors dkk.

    Scientific Reports, Vol. 14 No. 1 · 2024 · Inggris · DOAJ Scopus

    Abstract Anecdotal evidence from preliminary observations has noted multiple instances where osteoporosis is present in elderly patients before the clinical detection of bowel disease, even in the absence of overt gastrointestinal symptoms. However, any potential association between these…

  8. Artikel Jurnal Teks lengkap

    Radiomics: from qualitative to quantitative imaging

    William Rogers; Sithin Thulasi Seetha; Turkey Refaee dkk.

    British Journal of Radiology · 2020 · Inggris · OpenAlex Scopus

    Historically, medical imaging has been a qualitative or semi-quantitative modality. It is difficult to quantify what can be seen in an image, and to turn it into valuable predictive outcomes. As a result of advances in both computational hardware and machine learning algorithms, computers are…

  9. Artikel Jurnal Teks lengkap

    Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

    Simon Keek; Sebastian Sanduleanu; Frederik Wesseling dkk.

    PLOS ONE, Vol. 15 No. 5 · 2020 · Inggris · PLOS Scopus

    Introduction: In this study, we investigate the role of radiomics for prediction of overall survival (OS), locoregional recurrence (LRR) and distant metastases (DM) in stage III and IV HNSCC patients treated by chemoradiotherapy. We hypothesize that radiomic analysis of (peri-)tumoral tissue may…

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  10. Artikel Jurnal

    Automated detection and segmentation of non-small cell lung cancer computed tomography images

    Sergey P. Primakov; Abdalla Ibrahim; Janita E. van Timmeren dkk.

    Nature Communications, Vol. 13 No. 1 · 2022 · Inggris · DOAJ Scopus

    Correct interpretation of computer tomography (CT) scans is important for the correct assessment of a patient’s disease but can be subjective and timely. Here, the authors develop a system that can automatically segment the non-small cell lung cancer on CT images of patients and show in an in…

  11. Artikel Jurnal

    Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

    Martijn van der Heijden; Paul B. M. Essers; Monique C. de Jong dkk.

    Frontiers in Oncology, Vol. 9 · 2020 · Inggris · DOAJ Scopus

    Purpose: Tumor markers that are related to hypoxia, proliferation, DNA damage repair and stem cell-ness, have a prognostic value in advanced stage HNSCC patients when assessed individually. Here we aimed to evaluate and validate this in a multifactorial context and assess interrelation and the…