26 hasil untuk "Yuling Peng"

Knock down of target genes by RNA interference in the embryos of lepidopteran insect, Bombyx mori

Guanfeng Xu; Yulin Tian; Yuling Peng dkk.

STAR Protocols, Vol. 3 No. 1 · 2022 · Inggris · DOAJ Scopus

Summary: RNA interference (RNAi) is a technique used for posttranscriptional gene silencing, but lepidopteran insects are not sensitive to RNAi. Here, we present a protocol for knocking down the expression level of target genes by RNAi in Bombyx mori embryos. We describe the preparation of…

Mechanochemical synthesis of core-shell MWCNTs@acrylic resin nanoparticles with toughening effect on PVC composites

Yuling Peng; Wei Wang; Jie Zhang dkk.

Polymer Testing, Vol. 147 · 2025 · Inggris · DOAJ

Polyvinyl chloride (PVC) is inherently a brittle material, and enhancing its toughness while preserving its mechanical properties with minimal use of fillers remains a significant research challenge. In this paper, multi-walled carbon nanotubes (MWCNTs) coated with acrylic resin (ACR) were…

Analysis and prediction of the spatiotemporal characteristics of land-use ecological risk and carbon storage in Wuhan metropolitan area

Yuling Peng; Weiying Cheng; Xuexian Xu dkk.

Ecological Indicators, Vol. 158 · 2024 · Inggris · DOAJ Scopus

In the context of global warming, understanding the spatiotemporal dynamic of carbon storage, land-use related ecological risks, and how ecological risks are correlated with carbon storage, is vitally significant for enhancing regional carbon-sequestration capacity, promoting the rational…

Deep Medullary Vein and MRI Markers Were Related to Cerebral Hemorrhage Subtypes

Dan Wang; Yayun Xiang; Yuling Peng dkk.

Brain Sciences, Vol. 13 No. 9 · 2023 · Inggris · DOAJ Scopus

Background: To explore the performance of deep medullary vein (DMV) and magnetic resonance imaging (MRI) markers in different intracerebral hemorrhage (ICH) subtypes in patients with cerebral small vessel disease (CSVD). Methods: In total, 232 cases of CSVD with ICH were included in this study. The…

A high‐salt diet induces synaptic loss and memory impairment via gut microbiota and butyrate in mice

Chao Lei; Cong Liu; Yuling Peng dkk.

iMeta, Vol. 2 No. 2 · 2023 · Inggris · DOAJ Scopus

The RNA-binding protein Squid regulates embryonic midgut development via Axin alternative splicing in Bombyx mori

Chunmei Tong; Wanyu Mo; Minling Cai dkk.

Communications Biology, Vol. 9 No. 1 · 2026 · Inggris · DOAJ Scopus

Abstract The insect midgut is crucial for digestion and nutrient absorption, but its embryonic development is poorly understood. Here, we show that the RNA-binding protein Squid is essential for embryonic midgut epithelium development in the model insect, Bombyx mori. CRISPR/Cas9-mediated knockout…

Bmlark is essential for embryonic development

Yuling Peng; Jin Li; Kangkang Niu dkk.

BMC Genomics, Vol. 25 No. 1 · 2024 · Inggris · DOAJ Scopus

Abstract Background Transcription factor lark has been demonstrated to play multiple functions in Drosophila, but the function of this gene in embryonic development remains to be elucidated. Results In this study, the CRISPR/Cas9 gene-editing method was used to construct a Bmlark mutant strain of…

The Application of Diffusion Kurtosis Imaging on the Heterogeneous White Matter in Relapsing-Remitting Multiple Sclerosis

Qiyuan Zhu; Qiao Zheng; Dan Luo dkk.

Frontiers in Neuroscience, Vol. 16 · 2022 · Inggris · DOAJ Scopus

ObjectivesTo evaluate the microstructural damage in the heterogeneity of different white matter areas in relapsing-remitting multiple sclerosis (RRMS) patients by using diffusion kurtosis imaging (DKI) and its correlation with clinical and cognitive status.Materials and MethodsKurtosis fractional…

Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span

Zhongliang Hu; Yamei Luo; Yuting Liu dkk.

PLOS Biology, Vol. 21 No. 7 · 2023 · Inggris · PLOS Scopus

Global increase of life expectancy is rarely accompanied by increased health span, calling for a greater understanding of age-associated behavioral decline. Motor independence is strongly associated with the quality of life of elderly people, yet the regulators for motor aging have not been…

Doxifluridine promotes host longevity through bacterial metabolism

Rui Wei; Yuling Peng; Yamei Luo dkk.

PLOS Genetics, Vol. 21 No. 3 · 2025 · Inggris · PLOS Scopus

Aging is associated with alternative splicing (AS) defects that have broad implications on aging-associated disorders. However, which drug(s) can rescue age-related AS defects and extend lifespan has not been systematically explored. We performed large-scale compound screening in C. elegans using a…

The different damage patterns of short-, middle- and long-range connections between patients with relapse-remitting multiple sclerosis and neuromyelitis optica spectrum disorder

Xiaoya Chen; Yuling Peng; Qiao Zheng dkk.

Frontiers in Immunology, Vol. 13 · 2022 · Inggris · DOAJ Scopus

ObjectiveTo investigate the differences in short-, middle- and long-range connections between patients with relapse-remitting multiple sclerosis (RRMS) and neuromyelitis optica spectrum disorder (NMOSD), and their correlation with brain tissue volume, structural and functional network…

Quantitative Susceptibility Mapping-Derived Radiomic Features in Discriminating Multiple Sclerosis From Neuromyelitis Optica Spectrum Disorder

Zichun Yan; Huan Liu; Xiaoya Chen dkk.

Frontiers in Neuroscience, Vol. 15 · 2021 · Inggris · DOAJ Scopus

Objectives: To implement a machine learning model using radiomic features extracted from quantitative susceptibility mapping (QSM) in discriminating multiple sclerosis (MS) from neuromyelitis optica spectrum disorder (NMOSD).Materials and Methods: Forty-seven patients with MS (mean age = 40.00 ±…

One-day thermal regime extends the lifespan in Caenorhabditis elegans

Jichang Huang; Kai Wang; Mengqing Wang dkk.

Computational and Structural Biotechnology Journal, Vol. 21 · 2023 · Inggris · DOAJ Scopus

Environmental factors, including temperature, can modulate an animal’s lifespan. However, their underlying mechanisms remain largely undefined. We observed a profound effect of temperature on the aging of Caenorhabditis elegans (C. elegans) by performing proteomic analysis at different time points…

Correction: Endogenous retroviral ERVH48-1 promotes human urine cell reprogramming

Yuling Peng; Jieying Zhu; Qi Zhang dkk.

Cell Regeneration, Vol. 15 No. 1 · 2026 · Inggris · DOAJ Scopus

Endogenous retroviral ERVH48-1 promotes human urine cell reprogramming

Yuling Peng; Jieying Zhu; Qi Zhang dkk.

Cell Regeneration, Vol. 13 No. 1 · 2024 · Inggris · DOAJ Scopus

Abstract Endogenous retroviruses (ERVs), once thought to be mere remnants of ancient viral integrations in the mammalian genome, are now recognized for their critical roles in various physiological processes, including embryonic development, innate immunity, and tumorigenesis. Their impact on host…

MRI characteristics of brain edema in preeclampsia/eclampsia patients with posterior reversible encephalopathy syndrome

Hui Mai; Zhiyu Liang; Zhanhang Chen dkk.

BMC Pregnancy and Childbirth, Vol. 21 No. 1 · 2021 · Inggris · DOAJ Scopus

Abstract Background The neuroimaging manifestations of eclampsia and preeclampsia often overlap, mainly presenting as posterior reversible encephalopathy syndrome (PRES). The purpose of this retrospective study was to compare the extent and nature of brain edema in eclampsia and preeclampsia…

Disease-specific patterns of glymphatic-related dysfunction between multiple sclerosis and neuromyelitis optica spectrum disorder

Xiaoya Chen; Kai Zhang; Xiaojuan Dong dkk.

Frontiers in Immunology, Vol. 17 · 2026 · Inggris · DOAJ Scopus

BackgroundGlymphatic dysfunction has been reported in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), yet disease-specific patterns of glymphatic-related impairment and their structural and cognitive consequences remain poorly characterized.MethodsThis study enrolled 196…

Expansion of white matter hyperintensities is associated with the glymphatic system dysfunction in cerebral small vessel disease

Bang Zeng; Peng Zeng; Yayun Xiang dkk.

Brain Research Bulletin, Vol. 227 · 2025 · Inggris · DOAJ Scopus

Objectives: To explore the relationship between the glymphatic system and various patterns of white matter hyperintensities (WMHs) in the early stages of cerebral small vessel disease (CSVD), as well as their impact on cognitive function. Methods: The report included 84 patients with CSVD and 23…

Intragenic DNA methylation regulates insect gene expression and reproduction through the MBD/Tip60 complex

Guanfeng Xu; Hao Lyu; Yangqin Yi dkk.

iScience, Vol. 24 No. 2 · 2021 · Inggris · DOAJ Scopus

Summary: DNA methylation is an important epigenetic modification. However, the regulations and functions of insect intragenic DNA methylation remain unknown. Here, we demonstrate that a regulatory mechanism involving intragenic DNA methylation controls ovarian and embryonic developmental processes…

Estimation of ischemic core in acute ischemic stroke with CT angiography and non-contrast CT: Attenuation changes in ASPECTS regions vs. automated ASPECTS scoring

Jing Li; Yuling Peng; Jiayang Liu dkk.

Frontiers in Neuroscience, Vol. 16 · 2022 · Inggris · DOAJ Scopus

PurposeReperfusion therapies for acute ischemic stroke due to large-vessel occlusion (AIS-LVO) are highly time-dependent, and large infarction is related to poor outcomes and risk of symptomatic hemorrhage. It is of significance to investigate and optimize the screening means and selection criteria…