40,148 results
Showing 741–760 · 1.45 seconds · RSS
-
Journal Article Full text
The Role of Obesity in Type 2 Diabetes Mellitus—An Overview
Obesity or excessive weight gain is identified as the most important and significant risk factor in the development and progression of type 2 diabetes mellitus (DM) in all age groups. It has reached pandemic dimensions, making the treatment of obesity crucial in the prevention and management of…
-
Journal Article Full text
Electrocatalytic Nitrate and Nitrite Reduction toward Ammonia Using Cu 2 O Nanocubes: Active Species and Reaction Mechanisms
High Resolution Image Download MS PowerPoint Slide The electrochemical reduction of nitrate (NO 3 – ) and nitrite (NO 2 – ) enables sustainable, carbon-neutral, and decentralized routes to produce ammonia (NH 3 ). Copper-based materials are promising electrocatalysts for NO x – conversion to NH 3…
-
Journal Article Full text
IoT Based Soil pH Detection and Crop Recommendation System
Agricultural productivity hinges on soil fertility, influenced by key factors like nitrogen, phosphorus, potassium, pH level, and soil moisture. Yet, achieving optimal crop growth is challenging due to limited farmer knowledge and difficulties in determining precise fertilizer quantities…
-
Journal Article Full text
Rapid single-particle chemical imaging of nanoplastics by SRS microscopy
Plastics are now omnipresent in our daily lives. The existence of microplastics (1 µm to 5 mm in length) and possibly even nanoplastics (
-
Journal Article Full text
Recent advances in extracellular vesicles for therapeutic cargo delivery
Exosomes, which are nanosized vesicles secreted by cells, are attracting increasing interest in the field of biomedical research due to their unique properties, including biocompatibility, cargo loading capacity, and deep tissue penetration. They serve as natural signaling agents in intercellular…
-
Journal Article Full text
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study
In contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the…
-
Journal Article Full text
Optimizing scaffold pore size for tissue engineering: insights across various tissue types
microenvironment, directly influencing cellular interactions, migration, nutrient transfer, vascularization, and the formation of functional tissues. For optimal tissue formation, scaffold design must account for various parameters, including material composition, morphology, mechanical properties…
-
Journal Article Full text
Targeting cytokine and chemokine signaling pathways for cancer therapy
Cytokines are critical in regulating immune responses and cellular behavior, playing dual roles in both normal physiology and the pathology of diseases such as cancer. These molecules, including interleukins, interferons, tumor necrosis factors, chemokines, and growth factors like TGF-β, VEGF, and…
-
Journal Article Full text
Definition, classification and diagnosis of pulmonary hypertension
Pulmonary hypertension (PH) is a haemodynamic condition characterised by elevation of mean pulmonary arterial pressure (mPAP) >20 mmHg, assessed by right heart catheterisation. Pulmonary arterial wedge pressure (PAWP) and pulmonary vascular resistance (PVR) distinguish pre-capillary PH (PAWP ≤15…
-
Journal Article Full text
Review and Outlook on GaN and SiC Power Devices: Industrial State-of-the-Art, Applications, and Perspectives
We present a comprehensive review and outlook of silicon carbide (SiC) and gallium nitride (GaN) transistors available on the market for current and next-generation power electronics. Material properties and structural differences among GaN and SiC devices are first discussed. Based on the analysis…
-
Journal Article Full text
Status of Instructional Leadership Practices in Botswana's Public Technical and Vocational Education and Training: A Case of Brigades
This qualitative multi-case study explores instructional leadership practices at Botswana's brigades, a key provider of semi-skilled Technical and Vocational Education and Training (TVET) programmes. This study investigated the perspectives of instructional leaders and lecturers at two institutions…
-
Journal Article Full text
Amivantamab plus Lazertinib in Previously Untreated EGFR -Mutated Advanced NSCLC
Background Amivantamab plus lazertinib (amivantamab–lazertinib) has shown clinically meaningful and durable antitumor activity in patients with previously untreated or osimertinib-pretreated EGFR (epidermal growth factor receptor)–mutated advanced non–small-cell lung cancer (NSCLC). Methods In a…
-
Journal Article Full text
Comparison of In-Hospital Outcomes of Anterior Wall Versus Inferior Wall ST Elevation Myocardial Infarction Following Percutaneous Coronary Intervention: A Descriptive Cross-Sectional Study
Introduction ST-elevation myocardial infarction (STEMI) is a critical condition affecting many individuals worldwide, posing significant risks to patient health and outcomes. Different types of STEMI, such as anterior wall and inferior wall STEMI, can lead to varying in-hospital outcomes following…
-
Journal Article Full text
Breast cancer: A review of risk factors and diagnosis
Breast cancer remains a complex and prevalent health concern affecting millions of individuals worldwide. This review paper presents a comprehensive analysis of the multifaceted landscape of breast cancer, elucidating the diverse spectrum of risk factors contributing to its occurrence and exploring…
-
Journal Article Full text
Generative artificial intelligence, human creativity, and art
Recent artificial intelligence (AI) tools have demonstrated the ability to produce outputs traditionally considered creative. One such system is text-to-image generative AI (e.g. Midjourney, Stable Diffusion, DALL-E), which automates humans' artistic execution to generate digital artworks…
-
Journal Article Full text
The Dark Energy Survey: Cosmology Results with ∼1500 New High-redshift Type Ia Supernovae Using the Full 5 yr Data Set
Abstract We present cosmological constraints from the sample of Type Ia supernovae (SNe Ia) discovered and measured during the full 5 yr of the Dark Energy Survey (DES) SN program. In contrast to most previous cosmological samples, in which SNe are classified based on their spectra, we classify the…
-
Journal Article Full text
Review on the impact of heavy metals from industrial wastewater effluent and removal technologies
The incidence of water pollution in developing countries is high due to the lack of regulatory policies and laws that protect water bodies from anthropogenic activities and industrial wastewater. Industrial wastewater contains significant amounts of heavy metals that are detrimental to human…
-
Journal Article Full text
Neural general circulation models for weather and climate
Abstract General circulation models (GCMs) are the foundation of weather and climate prediction 1,2 . GCMs are physics-based simulators that combine a numerical solver for large-scale dynamics with tuned representations for small-scale processes such as cloud formation. Recently, machine-learning…
-
Journal Article Full text
Deterministic reprogramming of neutrophils within tumors
Neutrophils are increasingly recognized as key players in the tumor immune response and are associated with poor clinical outcomes. Despite recent advances characterizing the diversity of neutrophil states in cancer, common trajectories and mechanisms governing the ontogeny and relationship between…
Showing at most 50 pages. Narrow your search with filters for more specific results.